Bem-vindo! O Patuá tem por objetivo armazenar, preservar e dar visibilidade à produção científica em formato digital. O nome Patuá é uma alusão ao cesto utilizado pelos índios Asurini, para guardar e reunir pertences preciosos, como o conhecimento produzido pelos pesquisadores do IEC.

  • From molecules to behavior in long-term inorganic mercury intoxication: unraveling proteomic features in cerebellar neurodegeneration of rats 

    Bittencourt, Leonardo Oliveira; Chemelo, Victória Santos; Aragão, Walessa Alana Bragança; Puty, Bruna; Dionizio, Aline; Teixeira, Francisco Bruno; Fernandes, Mileni Silva; Silva, Márcia Cristina Freitas; Fernandes, Luanna Melo Pereira; Oliveira, Edivaldo Herculano Corrêa de; Buzalaf, Marilia Afonso Rabelo; Lopez, Maria Elena Crespo; Maia, Cristiane do Socorro Ferraz; Lima, Rafael Rodrigues (MDPI, 2022)
    Abstract: Mercury is a severe environmental pollutant with neurotoxic effects, especially when exposed for long periods. Although there are several evidences regarding mercury toxicity, little is known about inorganic ...
  • Epstein-Barr Virus (EBV) genotypes associated with the immunopathological profile of people living with HIV-1: immunological aspects of primary EBV infection 

    Pereira, Leonn Mendes Soares; França, Eliane dos Santos; Costa, Iran Barros; Lima, Igor Tenório; Freire, Amaury Bentes Cunha; Ramos, Francisco Lúzio de Paula; Monteiro, Talita Antonio Furtado; Macedo, Olinda; Sousa, Rita Catarina Medeiros; Freitas, Felipe Bonfim; Costa, Igor Brasil; Vallinoto, Antonio Carlos Rosário (MDPI, 2022)
    Background: The aim of the present study was to evaluate the immunological profile of adult HIV-1+ patients coinfected with primary Epstein-Barr virus (EBV) infection who were free of antiretroviral drugs and inhabitants ...
  • Epidemiology of the Epstein–Barr Virus in autoimmune inflammatory rheumatic diseases in Northern Brazil 

    França, Samires Avelino de Souza; Viana, Julimar Benedita Gomes de Oliveira; Góes, Hilda Carla Azevedo; Fonseca, Ricardo Roberto de Souza; Laurentino, Rogério Valois; Costa, Igor Brasil; Oliveira Filho, Aldemir Branco de; Machado, Luiz Fernando Almeida (MDPI, 2022)
    The present study aimed to describe the seroprevalence infection, Epstein-Barr virus (EBV) genotypes, relate the infection's profile with the epidemiological and corticotherapy data of patients with Autoimmune inflammatory ...
  • Effects of long-term fluoride exposure are associated with oxidative biochemistry impairment and global proteomic modulation, but not genotoxicity, in parotid glands of mice 

    Miranda, Giza Hellen Nonato; Lima, Leidiane Alencar de Oliveira; Bittencourt, Leonardo Oliveira; Santos, Sávio Monteiro dos; Souza, Michel Platini Caldas de; Nogueira, Lygia Sega; Oliveira, Edivaldo Herculano Corrêa de; Monteiro, Marta Chagas; Dionizio, Aline; Leite, Aline Lima; Pessan, Juliano Pelim; Buzalaf, Marília Afonso Rabelo; Lima, Rafael Rodrigues (Public Library of Science, 2022)
    Background: Fluoride has become widely used in dentistry because of its effectiveness in caries control. However, evidence indicates that excessive intake interferes with the metabolic processes of different tissues. Thus, ...
  • Endothelium activation during severe yellow fever triggers an intense cytokine-mediated inflammatory response in the liver parenchyma 

    Olímpio, Fábio Alves; Falcão, Luiz Fábio Magno; Carvalho, Marcos Luiz Gaia; Lopes, Jeferson da Costa; Mendes, Caio Cesar Henriques; Martins Filho, Arnaldo Jorge; Silva, Carlos Augusto Moreira da; Miranda, Vanessa do Socorro Cabral; Santos, Lais Carneiro dos; Vilacoert, Fellipe Souza da Silva; Cruz, Ana Cecília Ribeiro; Galúcio, Vanessa Costa Alves; Azevedo, Raimunda do Socorro da Silva; Martins, Lívia Caricio; Duarte, Maria Irma Seixas; Sousa, Jorge Rodrigues de; Vasconcelos, Pedro Fernando da Costa; Quaresma, Juarez Antônio Simões (MDPI, 2022)
    Yellow fever (YF) is a pansystemic disease caused by the yellow fever virus (YFV), the prototype species of the family Flaviviridae and genus Flavivirus, and has a highly complex host-pathogen relationship, in which ...

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