Polimorfismo do gene humano NRAMP1, níveis de anticorpos anti-PGL-1 e suscetibilidade para hanseníase em áreas endêmicas do Estado do Pará, Brasil
(Instituto Evandro Chagas, 2012)
O gene humano de resistência natural que codifica uma proteína detectada no macrófago – NRAMP1 parece estar envolvido com a influência no padrão de resposta imune à infecção por Mycobacterium leprae. Foi avaliada a associação ...
Environmental aspects related to tuberculosis and intestinal parasites in a low-income community of the Brazilian Amazon
(Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo, 2017)
We carried out a cross-sectional study from January to December 2015 on 1,425 inhabitants from a floating population in the Brazilian Amazon (Murinin district, Pará State) to describe the population-based prevalence of ...
Natural environmental water sources in endemic regions of northeastern Brazil are potential reservoirs of viable Mycobacterium leprae
(Instituto Oswaldo Cruz, 2017)
BACKGROUND: The detection of live Mycobacterium leprae in soil and animals other than humans suggests that the environment plays a role in the transmission of leprosy. OBJECTIVE: The objective of this study was to investigate ...
Detection of subclinical Mycobacterium leprae infection in children, contacts of leprosy cases, Fortaleza Ceará, Brazil
(British Leprosy Relief Assoc, 2017)
Objectives: To investigate the subclinical infection of leprosy in contacts younger than 15 years old of new leprosy cases diagnosed at the Dona Libania Dermatology Center in Fortaleza, Ceara. Methods: This was a ...
Presença de Mycobacterium leprae em escarro de paciente sintomático respiratório com hanseníase multibacilar
(Instituto Evandro Chagas, 2016)
Paciente com queixa principal de tosse produtiva crônica com três meses de duração e expectoração de muco purulento, perda de peso, falta de apetite, dispneia, dor na região torácica e cansaço, sendo ainda observados ...
Polymorphism of the cytocines genes TNFα, IFNγ, TGFβ, IL-6, and IL-10 in Hanseníase
(Sociedade Brasileira de Microbiologia, 2017)
Sensitivity of Anti-PGL-1 Elisa test using mixed antigens (disaccharide 1 trisaccharide) for the diagnosis and epidemiological surveillance of leprosy
(The International Federation of Anti-Leprosy Associations, 2018)
Introduction: The development of immunological and molecular diagnostic tests for leprosy has advanced substantially in the past decade, although such advances have not yet been effective in reducing the burden of leprosy ...
Discrimination based on sexual orientation against MSM in Brazil: a latent class analysis
(Associação Brasileira de Pós-Graduação em Saúde Coletiva, 2019)
Introduction: Discrimination based on sexual orientation can influence vulnerability to HIV, increasing exposure to risky sexual behavior among men who have sex with men (MSM). Objectives: To analyze data using latent ...
Analysis of potential household transmission events of tuberculosis in the city of Belem, Brazil
Tuberculosis (TB) is an infectious disease with a higher risk for infection and disease among household contacts (HHC). Here, we report a molecular epidemiology-based approach to study disease transmission and the ...