Crotoxin stimulates an M1 activation profile in murine macrophages during Leishmania amazonensis infection
(Cambridge University Press, 2017)
American tegumentary leishmaniasis is caused by different species of Leishmania. This protozoan employs several mechanisms to subvert the microbicidal activity of macrophages and, given the limited efficacy of current ...
Physalis angulata induces death of promastigotes and amastigotes of Leishmania (Leishmania) amazonensis via the generation of reactive oxygen species
Leishmaniasis are a neglected group of emerging diseases that have been found in 98 countries and are caused by protozoa of the genus Leishmania. The therapy for leishmaniasis causes several side effects and leads to ...
Medicinal plants from the Brazilian Amazonian region and their antileishmanial activity: a review
Leishmaniasis, a neglected disease caused by Leishmania protozoans, primarily affects people in tropical and subtropical areas. Chemotherapy based on the use of pentavalent antimonials, amphotericin B, paromomycin, miltefosine ...
Chemical characterisation of the constituents of Eugenia protenta McVaugh and leishmanicidal activity of dimethylxanthoxylin
(Taylor & Francis, 2017)
The chemical study of Eugenia protenta McVaugh extracts performed by classical and high-performance liquid chromatography techniques and spectral methods has led to the identification of known triterpenoids, flavonoids and ...
Hepatitis delta virus infection and Labrea hepatitis. Prevalence and role in fulminant hepatitis in the Amazon Basin
(American Medical Association, 1987)
To define more exactly the epidemiology of delta virus infection and confirm its role in causing fulminant Labrea hepatitis in the Amazon Basin, we studied the prevalence of delta virus infection among persons with acute ...
Biological effects of kojic acid on human monocytes in vitro
Monocytes are mononuclear phagocytes in peripheral blood that can differentiate into macrophages and dendritic cells. Macrophages play a specific role in the inflammatory process and are essential for the innate response. ...
A paruterinid metacestode in the liver of a Neotropical bat (Molossus molossus)
We describe a case of microscopic liver lesion caused by larval cestode in a frugivorous bat (Molossus molossus) from the Western Brazilian Amazon. Histopathological analysis of liver indicated the occurrence of metacestode ...
In vitro antileishmanial effects of Physalis angulata root extract on Leishmania infantum
OBJECTIVE: In the present study, we evaluated the effects of the aqueous extract of Physalis angulata root (AEPa) on Leishmania infantum proliferation, morphology, and the driving mechanism in leishmanicidal activity and ...
Memórias do Instituto Evandro Chagas, v. 8
(MS/SVS/Instituto Evandro Chagas, 2006)
Long‐term environmental enrichment reduces microglia morphological diversity of the molecular layer of dentate gyrus
(Federation of European Neuroscience Societies, 2020)
We investigated long-term environmental influences on morphology of microglia from the outer and middle thirds of molecular layer of the dentate gyrus (MolDG), and on microglia from dorsal and ventral dentate gyrus molecular ...