Seção que atua na área de vigilância epidemiológica desenvolvendo pesquisa e trabalhos ligados a área de impactos ambientais na Região Norte.

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  • Novel chalcones derivatives with potential antineoplastic activity investigated by docking and molecular dynamics simulations 

    M. Neto, Raimundo de A; Santos, Cleydson B. R; Henriques, Shayanne V. C; Machado, Letícia de O; Cruz, Jorddy Neves; Silva, Carlos H. T. de P. da; Federico, Leonardo B; Oliveira, Edivaldo Herculano Corrêa de; Souza, Michel P. C. de; Silva, Patrícia N. B. da; Taft, Carlton A; Ferreira, Irlon M; Gomes, Madson R. F (Taylor & Francis, 2020)
    Glioblastoma is an aggressive primary tumor of the central nervous system (CNS). Is the most aggressive among infiltrative gliomas arising from the CNS. This tumor has low patient survival rate and several studies aiming ...
  • Detection of viral hepatitis b and c in a metropolitan region in Northern Brazil 

    Oliveira, Maria Helena Cunha; Morais, Lena Líllian Canto de Sá; Costa, Fernanda Rafaela de Souza Rebelo da; Araújo, Lidineusa Machado; Valente, Andréa de Melo; Pereira, Michelle da Silva; Miranda, Antônio Marcos Mota; Guimarães, Ricardo José de Paula Souza e; Costa, Tássio Ricardo Martins da; Martins, Maria de Nazaré Rodrigues Pereira (2020)
    Objective: Analyze the SINAN epidemiological database for cases of viral hepatitis B and C, using the Linkage tools between the databases of the Laboratory Environment Manager (GAL) and the data from the Foundation of ...
  • Geochemical background concentrations of potentially toxic elements in soils of the Carajás Mineral Province, southeast of the Amazonian Craton 

    Lima, Mauricio Wilians de; Hamid, Sheryle Santos; Souza, Edna Santos de; Teixeira, Renato Alves; Palheta, Dulcidéia da Conceição; Faial, Kelson do Carmo Freitas; Fernandes, Antonio Rodrigues (Springer Verlag, 2020)
    The objective of this study was to establish background concentrations of potentially toxic elements (PTEs) in soils from the Carajás Mineral Province (CMP), southeastern Amazonian Craton. The PTEs Al, Ba, Cd, Co, Cr, Cu, ...
  • Copy number alterations in papillary thyroid carcinomas: does loss of SESN2 have a role in age-related different prognoses? 

    Almeida, Deise Cibele N. de; Souza, Michel Platini Caldas de; Amorim, Carolina Koury Nassar; Maués, Jersey Heitor da Silva; Sagica, Fernanda do Espirito Santo; Moreira-Nunes, Caroline Aquino; Oliveria, Edivaldo Herculano Corrêa de (International Institute of Anticancer Research, 2020)
    Background/Aim: Thyroid cancer is the only tumor in which age is an important prognostic factor. In papillary thyroid carcinomas (PTC), 45 years of age seems to be a key point that divides adult patients into two groups, ...
  • Meningiomas: an overview of the landscape of copy number alterations in samples from an admixed population 

    Silveira, Michele Amaral da; Ferreira, Wallax Augusto Silva; Amorim, Carolina Koury Nassar; Brito, José Reginaldo Nascimento; Kayath, André Salim; Sagica, Fernanda do Espirito Santo; Oliveira, Edivaldo Herculano Corrêa de (Hindawi Publishing Corporation, 2020)
    Meningiomas are considered the most common intracranial tumors, affecting mainly women. Studies in mixed populations can be of great importance to clarify issues related to the genetic diversity of tumors and their ...
  • Prevalence and risk indicators of non-carious cervical lesions in male footballers 

    Medeiros, Tamea Lacerda Monteiro; Mutran, Sheila Cristina Almeida Neves; Espinosa, Daybelis González; Faial, Kelson do Carmo Freitas; Pinheiro, Helder Henrique Costa; Couto, Roberta Souza D'Almeida (BMC, 2020)
    Background: Non-carious cervical lesions (NCCLs) have shown a significant incidence and prevalence and have been increasingly associated with people’s lifestyles and youths. This cross-sectional study aimed to determine ...
  • Chromosomal evolution in the phylogenetic context: a remarkable karyotype reorganization in neotropical Parrot Myiopsitta monachus (Psittacidae) 

    Furo, Ivanete de Oliveira; Krestschmer, Rafael; O'Brien, Patricia Caroline; Pereira, Jorge C; Garnero, Analía del Valle; Gunski, Ricardo José; O'Connor, Rebecca E; Griffin, Darren Karl; Gomes, Anderson José Baia; Ferguson-Smith, Malcom Andrew; Oliveira, Edivaldo Herculano Corrêa de (Frontiers Media, 2020)
    Myiopsitta monachus is a small Neotropical parrot (Psittaciformes: Arini Tribe) from subtropical and temperate regions of South America. It has a diploid chromosome number 2n = 48, different from other members of the Arini ...
  • Identifying novel genetic alterations in pediatric acute lymphoblastic leukemia based on copy number analysis 

    Batista-Gomes, Jéssica Almeida; Mello Júnior, Fernando Augusto Rodrigues; Oliveira, Edivaldo Herculano Corrêa de; Souza, Michel Platini Caldas de; Wanderley, Alayde Vieira; Pantoja, Laudreisa da Costa; Santos, Ney Pereira Carneiro dos; Khayat, Bruna Cláudia Meireles; Khayat, André Salim (BMC, 2020)
    Copy number variations (CNVs) analysis may reveal molecular biomarkers and provide information on the pathogenesis of acute lymphoblastic leukemia (ALL). We investigated the gene copy number in childhood ALL by microarray ...
  • The molecular cytogenetic characterization of conopophaga lineata indicates a common chromosome rearrangement in the parvorder furnariida (Aves, Passeriformes) 

    Oliveira, Thays Duarte de; Kretschmer, Rafael; Bertocchi, Natasha Ávila; O'Brien, Patricia C. M; Ferguson-Smith, Malcolm A; Garnero, Analía del Valle; Oliveira, Edivaldo Herculano Corrêa de; Gunski, Ricardo José (Sociedade Brasileira de Genética, 2020)
    Cytogenetic analyses of the Suboscines species are still scarce, and so far, there is no karyotype description of any species belonging to the family Conopophagidae. Thus, the aim of this study is to describe and analyze ...
  • Activated carbon obtained from amazonian biomass tailings (acai seed): Modification, characterization, and use for removal of metal ions from water 

    Queiroz, Leandro S; Souza, Luiz K. C. de; Thomaz, Kelly Taise C; Lima, Erika Tallyta Leite; Rocha Filho, Geraldo N. da; Nascimento, Luis Adriano S. do; Pires, Luiza H. de Oliveira; Faial, Kelson do Carmo Freitas; Costa, Carlos E. F. da (Elsevier, 2020)
    Acai seed was used herein as an Amazon biomass waste for the synthesis of activated and modified carbon in order to find a possible use for the large volume of residues generated during the processing of this fruit and to ...
  • PAH profiles in suspended particulate matter from an urbanized river within the Brazilian Amazon 

    Sousa, Larissa C; Rodrigues, C. C. S; Mendes, Rosivaldo de Alcântara; Corrêa, J. A. M (Springer, 2020)
    The distribution, seasonal variation and sources of 16 polycyclic aromatic hydrocarbons (PAH) from suspended particulate matter (SPM) of the Aurá River, a small amazon typical river located in Northern Brazil, were determined. ...
  • Historical demography and climate driven distributional changes in a widespread Neotropical freshwater species with high economic importance 

    Oliveira, E. A; Perez, M. F; Bertollo, L. A. C; Gestich, C. C; Ráb, P; Ezaz, T; Souza, F. H. S; Viana, P; Feldberg, E; Oliveira, Edivaldo Herculano Corrêa de; Cioffi, M. B (Wiley, 2020)
    The Neotropical region exhibits the greatest worldwide diversity and the diversification history of several clades is related to the puzzling geomorphologic and climatic history of this region. The freshwater Amazon ecoregion ...
  • Chromosomal evolution and phylogenetic considerations in cuckoos (Aves, Cuculiformes, Cuculidae) 

    Santos, Michelly da Silva dos; Kretschmer, Rafael; Furo, Ivanete de Oliveira; Gunski, Ricardo José; Garnero, Analía del Valle; Valeri, Mirela Pelizaro; O'Brien, Patricia C. M; Ferguson-Smith, Malcolm A; Oliveira, Edivaldo Herculano Corrêa de (Public Library of Science, 2020)
    The Cuckoos have a long history of difficult classification. The species of this order have been the subject of several studies based on osteology, behavior, ecology, morphology and molecular data. Despite this, the ...
  • A comprehensive cytogenetic analysis of several members of the family columbidae (Aves, columbiformes) 

    Kretschmer, Rafael; Furo, Ivanete de Oliveira; Gomes, Anderson José Baia; Kiazim, Lucas G; Gunski, Ricardo José; Garnero, Analía del Valle; Pereira, Jorge C; Ferguson-Smith, Malcolm A; Oliveira, Edivaldo Herculano Corrêa de; Griffin, Darren K; Freitas, Thales Renato Ochotorena de; O'Connor, Rebecca E (MDPI, 2020)
    The Columbidae species (Aves, Columbiformes) show considerable variation in their diploid numbers (2n = 68−86), but there is limited understanding of the events that shaped the extant karyotypes. Hence, we performed whole ...
  • Maternal and embryonic trace element concentrations and stable isotope fractionation in the smalleye smooth-hound (Mustelus higmani) 

    Araújo, Juliana de Souza; Andrades, Ryan; Lima, Marcelo de Oliveira; Hussey, Nigel E; Giarrizzo, Tommaso (Elsevier, 2020)
    Here, we evaluate maternal offloading of 16 trace elements (Essential: Co, Cr, Cu, Fe, Mn, Ni, Se and Zn; Nonessential: Al, As, Ba, Cd, Hg, Pb, Tl and U) and determine mother-offspring isotopic fractionation of δ13C and ...
  • Genotoxic effect of non-lethal concentrations of minocycline in human glial cell culture 

    Puty, Bruna; Nogueira, Iago César da Costa; Nogueira, Lygia S; Vasconcelos, Carolina Pinheiro; Araújo, Teka Mayara Corrêa; Bittencourt, Leonardo Oliveira; Ferreira, Railson de Oliveira; Oliveira, Edivaldo Herculano Correa de; Leal, Walace Gomes; Lima, Rafael Rodrigues (Elsevier, 2020)
    Minocycline has been proposed as a neuroprotective agent with pleiotropic effects on several experimental models of neurodegenerative diseases, including microglial inhibition. However, although most studies have focused ...
  • Methylmercury in predatory and non-predatory fish species marketed in the Amazon triple frontier 

    Silva, Stephani Ferreira da; Pereira, João Paulo Góes; Oliveira, Diomar Cavalcante; Lima, Marcelo de Oliveira (Springer, 2020)
    This study assessed if the concentrations of methylmercury (MeHg) in predatory and non-predatory fish caught in the Upper Solimões River are safe for human consumption, according to the reference values established by the ...
  • The distribution of 45s rDNA sites in bird chromosomes suggests multiple evolutionary histories 

    Degrandi, Tiago Marafiga; Gunski, Ricardo José; Garnero, Analía del Valle; Oliveira, Edivaldo Herculano Correa de; Krestschmer, Rafael; Souza, Marcelo Santos de; Barcellos, Suziane Alves; Hass, Iris (Sociedade Brasileira de Genética, 2020)
    The distribution of 45S rDNA cluster in avian karyotypes varies in different aspects, such as position, number of bearer chromosomes, and bearers being macro- or microchromosomes. The present study investigated the ...
  • The effect of three different pulp capping cements on mineralization of dental pulp stem cells 

    Petta, Thais de Mendonça; Pedroni, Ana Carla Fagundes; Saavedra, Daniela Feitosa; Faial, Kelson do Carmo Freitas; Marques, Márcia Martins; Couto, Roberta Souza D'Almeida (J-STAGE, 2020)
    This study evaluated the osteogenic differentiation of human dental pulp stem cells in response to substances released by the pulp capping agents, Biodentine (BD), mineral trioxide aggregate (MTA) and two-paste calcium ...
  • Genomic profiling reveals the pivotal role of hrHPV driving copy number and gene expression alterations, including mRNA downregulation of TP53 and RB1 in penile cancer 

    Macedo, Juliana; Silva, Elis; Nogueira, Leudivan; Coelho, Ronald; Silva, Jenilson da; Santos, Alcione dos; Teixeira Júnior, Antônio Augusto; Belfort, Marta; Silva, Gyl; Khayat, André; Oliveira, Edivaldo Herculano Corrêa de; Santos, Ana Paula dos; Cavalli, Luciane R; Pereira, Silma Regina (Wiley, 2020)
    The incidence of penile cancer (PeCa) is increasing worldwide, however, the highest rates are reported in underdeveloped countries. The molecular mechanisms that underly the onset and progression of these tumors are still ...

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