• First report of canine infection by leishmania (Viannia) guyanensis in the brazilian amazon 

  Santos, Francisco J. A; Nascimento, Luciana de Cássia Silva do; Silva, Wellington Bandeira da; Oliveira, Luciana P; Santos, Walter Souza; Aguiar, Délia Cristina Figueira; Santos, Lourdes Maria Garcez dos (MDPI, 2020)

  Abstract: The American cutaneous (CL) and visceral leishmaniasis (VL) are zooanthroponoses transmitted by sand flies. Brazil records thousands of human leishmaniasis cases annually. Dogs are reservoirs of Leishmania ...

• Polymorphism in the IL-1β promoter is associated with IgG antibody response to circumsporozoite protein repeats of Plasmodium vivax 

  Capobianco, Marcela Petrolini; Cassiano, Gustavo Capatti; Storti-Melo, Luciane Moreno; Pimenta, Tamirys Simão; Rodrigues, Ana Paula Drummond; Arruda, José Eduardo Gomes; Pinto, Marcia Ribeiro; Baptista, Andrea Regina de Souza; Pratt-Riccio, Lilian Rose; Bonini-Domingos, Cláudia Regina; Oliveira-Ferreira, Joseli de; Machado, Ricardo Luiz Dantas (Oxford University Press, 2020)

  BACKGROUND: It is well established that infection by Plasmodium vivax is a result of host-parasite interactions. In the present study, association with the IL1/IL2 cytokine profiles, anticircumsporozoite protein antibody ...

• Spatial analysis studies of endemic diseases for health surveillance: application of scan statistics for surveillance of tuberculosis among residents of a metropolitan municipality aged 60 years and above 

  Mesquita, Cristal Ribeiro; Enk, Martin Johannes; Guimarães, Ricardo José de Paula Souza e (Abrasco, 2020)

  Health surveillance aims to monitor adverse health events, and to set disease prevention and control goals, especially for communicable diseases, such as tuberculosis (TB).Older people have a higher risk of TB, due to their ...

• Clinical, cardiological and serologic follow-up of Chagas Disease in children and adolescents from the Amazon Region, Brazil: longitudinal study 

  Pinto, Ana Yecê das Neves; Valente, Vera da Costa; Valente, Sebastião Aldo da Silva; Motta, Tamires Anastácia Rodrigues; Ventura, Ana Maria Revorêdo da Silva (MDPI, 2020)

  Background:Outbreaks of Chagas disease (CD) by foodborne transmission is a problem related to deforestation, exposing people to triatomines infected by T. cruzi, in the Amazon region. Once involving long-time follow-up, ...

• Chronic methylmercury exposure causes spinal cord impairment: proteomic modulation and oxidative stress 

  Eiró, Luciana Guimarães; Ferreira, Maria Karolina Martins; Bittencourt, Leonardo Oliveira; Aragão, Walessa Alana Bragança; Souza, Michel Platini Caldas de; Silva, Marcia Cristina Freitas; Dionizio, Aline; Buzalaf, Marília Afonso Rabelo; Crespo-López, Maria Elena; Lima, Rafael Rodrigues (Elsevier, 2020)

  Methylmercury (MeHg) is considered by the World Health Organization (WHO) as one of the chemicals of greatest public health concern. Although central nervous system (CNS) is the main target organ, the effects over the ...

• The use of the circulating cathodic antigen (Cca) urine cassette assay for the diagnosis and assessment of cure of schistosoma mansoni infections in an endemic 

  Sousa, Sergei Rodrigo Magalhães de; Nogueira, Joyce Favacho Cardoso; Dias, Isabelle Helena Lima; Fonseca, Álvaro Luan Santana; Favero, Vivian; Geiger, Stefan Michael; Enk, Martin Johannes (Sociedade Brasileira de Medicina Tropical, 2020)

  INTRODUCTION: Schistosomiasis is a poverty-related disease that affects people in 78 countries worldwide. This study aimed to evaluate the point-of-care circulating cathodic antigen (POC-CCA) test performance using sensitive ...

• Clinical-epidemiological analysis of the care services at a special immunobiological reference center in the amazon 

  Espindola, Paula Rachel Neves; Soares, Gabrielly Lisboa da Silva; Pereira, Elizabeth do Socorro Pantoja; Oliveira, Kárila Larissa Pereira de; Brito, Jaira Ataide dos Santos de; Hora, Dinair Leal da; Chaves, Tânia do Socorro Souza (Universidade Federal do Paraná. Departamento de Enfermagem, 2020)

  Objective: to describe the clinical-epidemiological profile of the care service at the Reference Center for Special Immunobiologicals of Hospital in the Amazon. Method: a descriptive study, of a quantitative approach and ...

• Reactivity of purified and axenic amastigotes as a source of antigens to be used in serodiagnosis of canine visceral leishmaniasis 

  Silva, Thais Bruna Ferreira da; Silveira, Fernando Tobias; Tomokane, Thaise Yumie; Batista, Luis Fábio da Silva; Nunes, Juliana Barbosa; Matta, Vânia Lúcia Ribeiro da; Passero, Luiz Felipe Domingues; Laurenti, Márcia Dalastra (Elsevier, 2020)

  Although there is a great diversity of techniques and antigens used in the serodiagnosis of canine visceral leishmaniasis (CVL), total sensitivity and specificity have not yet been found. Since the use of amastigote forms ...

• Accuracy of real-time polymerase chain reaction to detect Schistosoma mansoni – infected individuals from an endemic area with low parasite loads 

  Magalhães, Fernanda do Carmo; Resende, Samira Diniz; Senra, Carolina; Graeff-Teixeira, Carlos; Enk, Martin Johannes; Coelho, Paulo Marcos Zech; Oliveira, Edward; Corrêa, Deborah Aparecida Negrão; Geiger, Stefan Michael; Carneiro, Mariângela (Cambridge University Press, 2020)

  Due to the efforts to control schistosomiasis transmission in tropical countries, a large proportion of individuals from endemic areas present low parasite loads, which hinders diagnosis of intestinal schistosomiasis by ...

• Association of cerebral malaria and TNF-alpha levels: a systematic review 

  Leão, Luana; Puty, Bruna; Dolabela, Maria Fâni; Povoa, Marinete Marins; Né, Yago Gecy de Sousa; Eiró, Luciana Guimarães; Fagundes, Nathália Carolina Fernandes; Maia, Lucianne Cople; Lima, Rafael Rodrigues (BMC, 2020)

  Background: Cerebral malaria is the most severe form of infection with Plasmodium falciparum characterized by a highly inflammatory response. This systematic review aimed to investigate the association between TNF-α ...

• Clinical and immunological features of human Leishmania (L.) infantum-Infection, novel insights Honduras, Central America 

  Sosa-Ochoa, Wilfredo; Zúniga, Concepción; Chaves, Luis Fernando; Flores, Gabriela Venicia Araújo; Pacheco, Carmen Maria Sandoval; Matta, Vania Lúcia Ribeiro da; Corbett, Carlos Eduardo Pereira; Silveira, Fernando Tobias; Laurenti, Marcia Dalastra (MDPI, 2020)

  Leishmania (Leishmania) infantum is the etiological agent of both American visceral leishmaniasis (AVL) and non-ulcerated cutaneous leishmaniasis (NUCL) in Honduras. Although AVL is the most severe clinical form of ...

• A doença de Chagas no município de Abaetetuba, Pará, Brasil 

  Viana, Lanaíde Lobato; Santos, Walter Souza; Alves, Veracilda Ribeiro; Bichara, Cléa Nazaré Carneiro; Pontes, Altem Nascimento (Núcleo de Produções Científicas da Uniara, 2020)

  Traçar o perfil epidemiológico da doença de Chagas aguda em Abaetetuba/ Pará, entre 2007 a 2017. Foram analisados dados secundários da Prefeitura de Abaetetuba, Secretaria de Saúde Pública do Estado do Pará e do Sistema ...

• Malaria transmission and individual variability of the naturally acquired IgG antibody against the Plasmodium vivax blood-stage antigen in an endemic area in Brazil 

  Costa, Edna Maria F; Amador, Ednei Charles C; Silva, Eliane S; Alvarenga, Cassiana O; Pereira, Pedro Elias; Póvoa, Marinete Marins; Cunha, Maristela G (Elsevier, 2020)

  Plasmodium vivax remains an important cause of malaria in South America and Asia, and analyses of the antibody immune response are being used to identify biomarker of parasite exposure. The IgG antibody naturally acquired ...

• New record of preclinical diagnosis of American visceral leishmaniasis in Amazonian Brazil encourages optimizing disease control 

  Lima, Luciana; Santos, Thiago Vasconcelos dos; Campos, Marliane Batista; Ramos, Patrícia Karla; Gomes, Claudia; Laurenti, Marcia; Matta, Vania da; Corbett, Carlos; Silveira, Fernando Tobias (Elsevier, 2020)

  The clinical-immunological spectrum of human Leishmania (L.) infantum chagasi-infection in Amazonian Brazil has recently been reviewed based on the combined use of the delayed-type hypersensitivity (DTH) and indirect ...

• Surveillance of cutaneous leishmaniasis in clinical samples: distribution of Leishmania guyanensis in the state of Amapá, Brazil, 2018 

  Almeida, Ariely Nunes Ferreira de; Nascimento, Luciana de Cássia Silva do; Sousa, Edith Silvia Moura de Moura; Oliveira, Afonso José Diger de; Sena, Maria Gorete de; Resende, Breno Maués de; Chaves, Raimunda Cleide Gonçalves; Santos, Lourdes Maria Garcez dos (Ministério da Saúde. Secretaria de Vigilância em Saúde, 2020)

  Objective: to investigate Leishmania species in a series of autochthonous cutaneous leishmaniasis (CL) cases in Amapá State, Brazilian Amazon. Methods: this was a descriptive ecological study carried out from January-October/2018 ...

• The next big threat to global health? 2019 novel coronavirus (2019-nCoV): What advice can we give to travellers? – Interim recommendations January 2020, from the Latin-American society for Travel Medicine (SLAMVI) 

  Biscayart, Cristian; Angeleri, Patricia; Lloveras, Susana; Chaves, Tânia do Socorro Souza; Schlagenhauf, Patricia; Rodríguez-Morales, Alfonso J (Elsevier, 2020)

• Increasing putative vector importance of Trichophoromyia phlebotomines (Diptera: Psychodidae) 

  Santos, Thiago Vasconcelos dos; Silveira, Fernando Tobias (Instituto Oswaldo Cruz, 2020)

  Despite some phlebotomines being well recognised as vectors of leishmaniasis agents, vector importance of those belonging to the genus Trichophoromyia has not been extensively studied. The present study provides evidence ...

• Scanning electron microscopy of sand flies of the Chagasi series, Psychodopygus (Diptera: Psychodidae) genus, focusing on the genitalia 

  Godoy, Rodrigo Espíndola; Rangel, Elizabeth Ferreira; Mallet, Jacenir Reis dos Santos; Santos, Thiago Vasconcelos dos; Barata, Iorlando da Rocha; Pessoa, Felipe Arley costa; Cunha, Alda Eunice Farias Lobato da; Vilela, Maurício Luiz; Galati, Eunice Aparecida Bianchi (Oxford University Press, 2020)

  Males of cryptic or closely related species present great morphological variation in their genitalia, whereas females, such as those of the Chagasi Series of the Psychodopygus Mangabeira, 1941 genus, are more similar. ...

• Phlebotomines (Diptera: Psychodidae) from a urban park of Belém, Pará state, northern Brazil and potential implications in the transmission of american cutaneous leishmaniasis 

  Uzcátegui, Yetsenia del Valle Sánchez; Santos, Thiago Vasconcelos dos; Silveira, Fernando Tobias; Ramos, Patricia Karla Santos; Santos, Eduardo José M dos; Póvoa, Marinete Marins (Oxford University Press, 2020)

  In urban ecotourism parks, the life cycle of American cutaneous leishmaniasis (ACL) agents can remain established, where phlebotomines may comprise potential risks for visitors. The present study aimed to survey the ...

• Naphthoquinones isolated from Eleutherine plicata herb: in vitro antimalarial activity and molecular modeling to investigate their binding modes 

  Vale, Valdicley Vieira; Cruz, Jorddy Neves; Viana, Giselle Maria Rachid; Póvoa, Marinete Marins; Brasil, Davi do Socorro Barros; Dolabela, Maria Fani (Springer Verlag, 2020)

  Plasmodium falciparum is the cause of malaria and has become resistant to the drugs used to treat the disease. Therefore, the development for novel compounds with antimalarial activity has become urgent. Plant species, ...

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