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Experimental infection of golden hamsters with Guama virus (Peribunyaviridae, Orthobunyavirus)
(Elsevier, 2019)
The Guama virus (GMAV) is a member of Peribunyaviridae family, Orthobunyavirus genus. Several strains of the
virus were isolated in South and Central Americas from several hosts, such as humans, wild animals, including
nonhuman ...
In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus
(Nature Publishing Group, 2018)
Zika virus (ZIKV) has recently caused a pandemic disease, and many cases of ZIKV infection in pregnant
women resulted in abortion, stillbirth, deaths and congenital defects including microcephaly, which
now has been ...
In situ inflammasome activation results in severe damage to the central nervous system in fatal Zika virus microcephaly cases
(Elsevier, 2018)
Zika virus (ZIKV) has caused substantial concern worldwide owing to its association with severe birth defects, such as microcephaly and other congenital malformations. Inflammasomes, i.e., multi-protein complexes that ...
First isolation of West Nile virus in Brazil
(Instituto Oswaldo Cruz, 2019)
BACKGROUND Serological evidence of West Nile virus (WNV) infection has been reported in different regions of Brazil from
equine and human hosts but the virus had never been isolated in the country.
OBJECTIVES We sought ...
Prenatal disorders and congenital Zika syndrome in squirrel monkeys
(Nature Research, 2021)
During the Zika virus (ZIKV) outbreak in Brazil (2015–2016), the clinical manifestations associated with its infection were complex and included miscarriage and congenital malformations, not previously described. In this ...
Histopathological lesions of congenital Zika syndrome in newborn squirrel monkeys
(Nature Research, 2021)
The absence of an adequate animal model for studies has limited the understanding of congenital Zika syndrome (CZS) in humans during the outbreak in America. In this study, we used squirrel monkeys (Saimiri collinsi), a ...
Correlation between apoptosis and in situ immune response in fatal cases of microcephaly caused by Zika Virus
(Elsevier, 2018)
Zika virus (ZIKV) is a single-stranded positive-sense RNA flavivirus that possesses a genome approximately 10.7 Kb in length. Although pro-inflammatory and anti-inflammatory cytokines and apoptotic markers belonging to the ...