In situ inflammasome activation results in severe damage to the central nervous system in fatal Zika virus microcephaly cases
Zika virus (ZIKV) has caused substantial concern worldwide owing to its association with severe birth defects, such as microcephaly and other congenital malformations. Inflammasomes, i.e., multi-protein complexes that ...
Correlation between apoptosis and in situ immune response in fatal cases of microcephaly caused by Zika Virus
Zika virus (ZIKV) is a single-stranded positive-sense RNA flavivirus that possesses a genome approximately 10.7 Kb in length. Although pro-inflammatory and anti-inflammatory cytokines and apoptotic markers belonging to the ...