Surto de raiva humana transmitida por morcegos no Município de Portel-Pará, março/abril de 2004
(Ministério da Saúde. Secretaria de Vigilância em Saúde, 2004)
An epidemic of sylvatic yellow fever in the Southeast region of Maranhao State, Brazil, 1993-1994: epidemiologic and entomologic findings
(American Society of Tropical Medicine and Hygiene, 1997)
Yellow fever virus transmission was very active in Maranhao State in Brazil in 1993 and 1994. An investigation was carried out to evaluate the magnitude of the epidemic. In 1993, a total of 932 people was examined for ...
Estudo experimental sobre a patogenicidade do Vírus Ilhéus em hamsters dourados (Mesocricetus auratus)
(Instituto Evandro Chagas, 2010)
Visando investigar a patogenicidade do Flavivirus Ilhéus (VILH) foi inoculada, via intraperitoneal, 9,8 DL de suspensão 50 viral em hamsters dourados jovens (Mesocricetus auratus) e, diariamente, soros e vísceras (cérebro, ...
Functional aspects, phenotypic heterogeneity, and tissue immune response of macrophages in infectious diseases
(Dove Medical Press, 2019)
Macrophages are a functionally heterogeneous group of cells with specialized functions depending not only on their subgroup but also on the function of the organ or tissue in which the cells are located. The concept of ...
Experimental infection of golden hamsters with Guama virus (Peribunyaviridae, Orthobunyavirus)
The Guama virus (GMAV) is a member of Peribunyaviridae family, Orthobunyavirus genus. Several strains of the virus were isolated in South and Central Americas from several hosts, such as humans, wild animals, including nonhuman ...
In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus
(Nature Publishing Group, 2018)
Zika virus (ZIKV) has recently caused a pandemic disease, and many cases of ZIKV infection in pregnant women resulted in abortion, stillbirth, deaths and congenital defects including microcephaly, which now has been ...
In situ inflammasome activation results in severe damage to the central nervous system in fatal Zika virus microcephaly cases
Zika virus (ZIKV) has caused substantial concern worldwide owing to its association with severe birth defects, such as microcephaly and other congenital malformations. Inflammasomes, i.e., multi-protein complexes that ...
First isolation of West Nile virus in Brazil
(Instituto Oswaldo Cruz, 2019)
BACKGROUND Serological evidence of West Nile virus (WNV) infection has been reported in different regions of Brazil from equine and human hosts but the virus had never been isolated in the country. OBJECTIVES We sought ...
Yellow fever virus modulates cytokine mRNA expression and induces activation of caspase 3/7 in the human hepatocarcinoma cell line HepG2
(Springer Verlag, 2019)
Yellow fever virus (YFV) penetrates the skin through the bite of a vector mosquito and spreads to various organs, mainly the liver, where it causes lesions and induces necrosis and apoptosis. We evaluated the mRNA expression ...
Prenatal disorders and congenital Zika syndrome in squirrel monkeys
(Nature Research, 2021)
During the Zika virus (ZIKV) outbreak in Brazil (2015–2016), the clinical manifestations associated with its infection were complex and included miscarriage and congenital malformations, not previously described. In this ...