Surto de raiva humana transmitida por morcegos no Município de Portel-Pará, março/abril de 2004
(Ministério da Saúde. Secretaria de Vigilância em Saúde, 2004)
An epidemic of sylvatic yellow fever in the Southeast region of Maranhao State, Brazil, 1993-1994: epidemiologic and entomologic findings
(American Society of Tropical Medicine and Hygiene, 1997)
Yellow fever virus transmission was very active in Maranhao State in Brazil in 1993 and 1994. An investigation was carried out to evaluate the magnitude of the epidemic. In 1993, a total of 932 people was examined for ...
Estudo experimental sobre a patogenicidade do Vírus Ilhéus em hamsters dourados (Mesocricetus auratus)
(Instituto Evandro Chagas, 2010)
Visando investigar a patogenicidade do Flavivirus Ilhéus (VILH) foi inoculada, via intraperitoneal, 9,8 DL de suspensão 50 viral em hamsters dourados jovens (Mesocricetus auratus) e, diariamente, soros e vísceras (cérebro, ...
Functional aspects, phenotypic heterogeneity, and tissue immune response of macrophages in infectious diseases
(Dove Medical Press, 2019)
Macrophages are a functionally heterogeneous group of cells with specialized functions depending not only on their subgroup but also on the function of the organ or tissue in which the cells are located. The concept of ...
Experimental infection of golden hamsters with Guama virus (Peribunyaviridae, Orthobunyavirus)
The Guama virus (GMAV) is a member of Peribunyaviridae family, Orthobunyavirus genus. Several strains of the virus were isolated in South and Central Americas from several hosts, such as humans, wild animals, including nonhuman ...
In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus
(Nature Publishing Group, 2018)
Zika virus (ZIKV) has recently caused a pandemic disease, and many cases of ZIKV infection in pregnant women resulted in abortion, stillbirth, deaths and congenital defects including microcephaly, which now has been ...
First isolation of West Nile virus in Brazil
(Instituto Oswaldo Cruz, 2019)
BACKGROUND Serological evidence of West Nile virus (WNV) infection has been reported in different regions of Brazil from equine and human hosts but the virus had never been isolated in the country. OBJECTIVES We sought ...
Correlation between apoptosis and in situ immune response in fatal cases of microcephaly caused by Zika Virus
Zika virus (ZIKV) is a single-stranded positive-sense RNA flavivirus that possesses a genome approximately 10.7 Kb in length. Although pro-inflammatory and anti-inflammatory cytokines and apoptotic markers belonging to the ...
Histopathological lesions of congenital Zika syndrome in newborn squirrel monkeys
(Nature Research, 2021)
The absence of an adequate animal model for studies has limited the understanding of congenital Zika syndrome (CZS) in humans during the outbreak in America. In this study, we used squirrel monkeys (Saimiri collinsi), a ...
Prenatal disorders and congenital Zika syndrome in squirrel monkeys
(Nature Research, 2021)
During the Zika virus (ZIKV) outbreak in Brazil (2015–2016), the clinical manifestations associated with its infection were complex and included miscarriage and congenital malformations, not previously described. In this ...