• Whole-genome sequencing of Leishmania infantum chagasi isolates from Honduras and Brazil 

  Silveira, Fernando Tobias; Sousa Junior, Edivaldo Costa; Silvestre, Rodrigo Vellasco Duarte; Martins, André Guilherme Costa; Pinheiro, Kenny da Costa; Ochoa, Wilfredo Sosa; Santos, Thiago Vasconcelos dos; Ramos, Patrícia Karla; Casseb, Samir Mansour Moraes; Silva, Sandro Patroca da; Valeriano, Concepción Zúniga; Lima, Luciana Vieira; Campos, Marliane Batista; Matta, Vania Lucia da; Gomes, Claudia Maria; Flores, Gabriela Venicia; Pacheco, Carmen Maria; Corbett, Carlos Eduardo; Nakaya, Helder; Laurenti, Márcia Dalastra (American Society for Microbiology, 2021)

  This work reports on the whole-genome sequencing of Leishmania infantum chagasi from Honduras (Central America) and Brazil (South America).

• Regulation of the immune checkpoint indoleamine 2,3-dioxygenase expression by Epstein–Barr Virus 

  Sawada, Leila; Vallinoto, Antônio Carlos Rosário; Costa, Igor Brasil (MDPI, 2021)

  Epstein–Barr virus (EBV) is an oncovirus ubiquitously distributed and associated with different types of cancer. The reason why only a group of infected people develop cancer is still unknown. EBV-associated cancers represent ...

• Detection of Epstein-Barr virus in gastric adenocarcinoma: qPCR and fish comparison 

  Costa, Igor Brasil; Souza, Carolina Rosal Teixeira de; Costa, Iran Barros; Santos, Liann Filiphe Pereira dos; Paixão, Luana César Ferraz; Polaro, Alessandra Alves; Monteiro, Talita Antônia Furtado; Burbano, Rommel Mário Rodríguez (Springer, 2022)

  EBV-associated gastric cancer accounts for about 10% of all gastric carcinomas worldwide. We aimed to verify the prevalence of EBV in gastric adenocarcinoma samples using FISH and qPCR and comparing the results obtained ...

• Simultaneous occurrence of Epstein-Barr virus (EBV) in periodontal pockets and in oral squamous cell carcinoma: a cross-sectional study 

  Santos, Humberto Jácome; Silva, Naira da Silva e; Resende, Renata Gonçalves; Pinheiro, Helder Henrique Costa; Machado, Luiz Fernando Almeida; Silva, Guilherme de Souza; Costa, Fernando de Oliveira; Costa, Igor Brasil; Alves, Ana Cláudia Braga Amoras; Mesquita, Ricardo Alves; Alves Junior, Sérgio de Melo (Springer, 2021)

  Objectives: This study aimed to investigate the detection of Epstein-Barr virus (EBV) in oral squamous cell carcinoma (OSCC) and to verify the concordance of EBV-DNA frequency in subgingival sites and in the OSCC. Methods: ...

• Retrospective molecular analysis of norovirus recombinant strains in the amazon region, Brazil 

  Portela, Ana Caroline Rodrigues; Hernandez, Juliana Merces; Bandeira, Renato da Silva; Sousa Júnior, Edivaldo Costa; Melo, Taynah Cohen de; Lucena, Maria Silvia Souza; Teixeira, Dielle Monteiro; Siqueira, Jones Anderson Monteiro; Gabbay, Yvone Benchimol; Silva, Luciana Damascena da (Elsevier, 2021)

  Background: Noroviruses are enteric viruses that cause acute gastroenteritis worldwide. Over two decades, GII.4 genotype was responsible for most cases. However, recombinant strains have emerged and changed the epidemiological ...

• Epidemiological risk factors associated with primary infection by Epstein-Barr virus in HIV-1-positive subjects in the Brazilian Amazon region 

  Pereira, Leonn Mendes Soares; França, Eliane dos Santos; Costa, Iran Barros; Lima, Igor Tenório; Freire, Amaury Bentes Cunha; Ramos, Francisco Lúzio de Paula; Monteiro, Talita Antonia Furtado; Macedo, Olinda; Sousa, Rita Catarina Medeiros; Freitas, Felipe Bonfim; Costa, Igor Brasil; Vallinoto, Antonio Carlos Rosário (Nature Research, 2021)

  To identify the prevalence and risk factors for primary Epstein–Barr virus (EBV) infection in human immunodeficiency virus (HIV)-1-positive adult treatment-naïve patients between January 2018 and December 2019 in a state ...

• Prevalence and factors associated with syphilis in people living with HIV/AIDS in the state of Para, Northern Brazil 

  Fontes Neto, Pedro Leão; Fonseca, Ricardo Roberto de Souza; Avelino, Maria Eduarda de Sousa; Vilhena, Elizandro Monteiro; Barbosa, Maria dos Anjos de Abreu Pina; Lopes, Carmen Andrea Freitas; Gomes, Samara Tatielle Monteiro; Sequeira, Bianca Jorge; Laurentino, Rogério Valois; Freitas, Felipe Bonfim; Oliveira Filho, Aldemir Branco de; Machado, Luiz Fernando Almeida (Frontiers Media, 2021)

  Syphilis continues to be a public health problem worldwide and its incidence has increased in people living with HIV/AIDS in recent years. This study determined the prevalence and factors associated with syphilis in people ...

• Detection of a novel species A, DS-1-like, G4P[6] rotavirus strain from a Brazilian child with gastroenteritis 

  Bandeira, Renato da Silva; Souto, Lizandra Caroline dos Santos; Souza, Layse Costa de; Linhares, Alexandre da Costa; Mascarenhas, Joana D’Arc Pereira (Wiley, 2021)

  Rotaviruses belonging to species A (RVA) remain among the most common causes of severe gastroenteritis in children aged <5 years, leading to substantial morbidity and mortality worldwide. Genome reassortment events between ...

• Molecular analysis of G3P[6] rotavirus in the Amazon region of Brazil: evidence of reassortment with equine-like strains 

  Serra, Ana C. Silva; Sousa Júnior, Edivaldo costa; Cruz, Jonas F; Lobo, Patrícia dos Santos; Penha Júnior, Edvaldo Tavares da; Bandeira, Renato S; Bezerra, Delana Andreza Melo; Mascarenhas, Joana D’Arc Pereira; Guerra, Sylvia de Fátima dos Santos; Soares, Luana da Silva (Future Science Group, 2021)

  Aim: To perform a molecular analysis of rotavirus A (RVA) G3P[6] strains detected in 2012 and 2017 in the Amazon region of Brazil. Materials & methods: Eighteen RVA G3P[6] strains were collected from children aged under ...

• Further considerations about Detection and identification of enteroviruses circulating in children with acute gastroenteritis in Para State, Northern Brazil (2010-2011) 

  Machado, Raiana Scerni; Sousa Júnior, Ivanildo Pedro de; Monteiro, Jacqueline Cortinhas; Ferreira, James Lima; Alves, Jainara Cristina dos Santos; Tavares, Fernando Neto (BMC, 2021)

  On the detection and identifcation of enteroviruses circulating in children with acute gastroenteritis in Brazil: reply to Luchs, A. Comments on Detection and identifcation of enteroviruses circulating in children with ...

• Jejunal injuries in captive marmosets affected by chronic wasting disease 

  Pereira, Washington Luiz Assunção; Diniz Junior, José Antônio Picanço; Muniz, José Augusto Pereira Carneiro; Souza, Alex Junior Souza de; Mendes, Fernanda Figueiredo; Cecim, Amanda Desirée Assunção; Aguirra, Lucien Roberta Valente Miranda de (MS/SVS/Instituto Evandro Chagas, 2021)

  INTRODUCTION: Wasting marmoset syndrome affects the Callitrichidae family reared in captivity, characterized by progressive muscle-weakening and wasting conditions. It has been one of the main causes of death in primates ...

• Diagnosis of intestinal amebiasis using coproscopic and immunological methods in a population sample in Greater Metropolitan Belém, Pará, Brazil 

  Póvoa, Marinete Marins; Arruda, José Eduardo Gomes; Silva, Mônica Cristina de Moraes; Bichara, Cléa Nazaré Carneiro; Esteves, Paulo; Gabbay, Yvone Benchimol; Machado, Ricardo Luiz Dantas (Fiocruz. Escola Nacional de Saúde Pública Sergio Arouca, 2000)

  We compare diagnostic methods for Entamoeba histolytica in fecal samples from the city of Belém, Pará, Brazil. We analyze stool samples from children and adults (Group I); stool and serum samples from adults (Group II); ...

• The burden of norovirus disease in children: a multi-country study in Chile, Brazil, Thailand and the Philippines 

  Safadi, Marco Aurelio; Riera-Montes, Margarita; Bravo, Lulu; Tangsathapornpong, Auchara; Lagos, Rasanna; Thisyakorn, Usa; Linhares, Alexandre da Costa; Capeding, Rose; Prommalikit, Olarn; Verstraeten, Thomas; O'Ryan, Miguel (Elsevier, 2021)

  Background: Noroviruses (NoVs) cause acute gastroenteritis (AGE) worldwide, affecting children in particular. We aimed to estimate the burden of disease due to NoV among children aged <6 years in Brazil, Chile, Philippines ...

• PD-L1 expression associated with Epstein-Barr virus status and patients survival in a large cohort of gastric cancer patients in northern Brazil 

  Moreira-Nunes, Caroline de Fátima Aquino; Martins, Cláudia Nazaré de Souza Almeida Titan; Feio, Danielle; Lima, Isamu Komatsu; Lamarão, Leticia Martins; Souza, Carolina Rosal Teixeira de; Costa, Igor Brasil; Maués, Jersey Heitor da Silva; Soares, Paulo Cardoso; Assumpção, Paulo Pimentel de; Burbano, Rommel Mário Rodrígues (MDPI, 2021)

  Abstract: Gastric cancer (GC) is a worldwide health problem, making it one of the most common types of cancer, in fifth place of all tumor types, and the third highest cause of cancer deaths in the world. There is a ...

• Neurological disease caused by Oropouche virus in northern Brazil: should it be included in the scope of clinical neurological diseases? 

  Chiang, Jannifer Oliveira; Azevedo, Rafael S; Justino, Maria Cleonice Aguiar; Matos, Haroldo José de; Cabeça, Hideraldo L. S; Silva, Sandro Patroca da; Henriques, Daniele Freitas; Silva, Eliana Vieira Pinto da; Andrade, Gabriela S. S; Vasconcelos, Pedro Fernando da Costa; Martins, Lívia Carício; Azevedo, Raimunda do Socorro da Silva (Springer, 2021)

  We describe two neurological cases of Oropouche virus infection in northern Brazil, where the virus is endemic but neglected as a pathogen. This study reiterates the necessity of developing protocols for diagnosing ...

• Rotavírus: gastroenterite e outras infecções por vírus entéricos 

  Linhares, Alexandre da Costa; Justino, Maria Cleonice Aguiar; Mascarenhas, Joana D’Arc Pereira; Farias, Luana da Silva Soares; Gabbay, Yvone Benchimol; Resque, Hugo Reis (Atheneu, 2021)

• Prevalence of high risk HPV in HIV-Infected women from Belem, Para, Amazon Region of Brazil: a cross-sectional study 

  Monteiro, Jacqueline Cortinhas; Fonseca, Ricardo Roberto de Souza; Ferreira, Tuane Carolina de Sousa; Rodrigues, Luana Lorena Silva; Silva, Andreza Reis Brasil da; Gomes, Samara Tatielle; Silvestre, Rodrigo Vellasco Duarte; Silva, Andréa Nazaré Monteiro Rangel; Pamplona, Ilze; Vallinoto, Antonio Carlos Rosário; Ishak, Ricardo; Machado, Luiz Fernando Almeida (Frontiers Media, 2021)

  Human papillomavirus (HPV) is the most common sexually transmitted infection in the world. Several studies have shown a higher prevalence of HPV infection in HIV-infected women. The aim of this study was to determine the ...

• Evolutionary dynamics and dissemination pattern of the SARS-CoV-2 lineage B.1.1.33 during the early pandemic phase in Brazil 

  Resende, Paola Cristina; Delatorre, Edson; Graf, Tiago; Mir, Daiana; Motta, Fernando Couto; Appolinario, Luciana Reis; Paixão, Anna Carolina Dias da; Mendonça, Ana Carolina da Fonseca; Ogrzewalska, Maria; Caetano, Braulia; Wallau, Gabriel Luz; Docena, Cássio; Santos, Mirleide Cordeiro dos; Ferreira, Jessylene de Almeida; Sousa Júnior, Edivaldo Costa; Silva, Sandro Patroca da; Fernandes, Sandra Bianchini; Vianna, Lucas Alves; Souza, Larissa da Costa; Ferro, Jean F. G; Nardy, Vanessa B; Santos, Cliomar A; Riediger, Irina; Debur, Maria do Carmo; Croda, Júlio; Oliveira, Wanderson Kleber; Abreu, André; Bello, Gonzalo; Siqueira, Marilda M (Frontiers Media, 2021)

  A previous study demonstrates that most of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Brazilian strains fell in three local clades that were introduced from Europe around late February 2020. Here we ...

• Comparing quality of reporting between preprints and peer-reviewed articles in the biomedical literature 

  Carneiro, Clarissa F. D; Queiroz, Victor G. S; Moulin, Thiago C; Carvalho, Carlos A. M; Hass, Clarissa B; Rayêe, Danielle; Henshall, David E; Souza, Evandro A. de; Espinelli, Felippe; Boss, Flávia Z; Guercio, Gerson D; Costa, Igor R; Hajdu, Karina L; Modrák, Martin; Tan, Pedro B; Burgess, Steven J; Guerra, Sylvia de Fátima dos Santos; Bortoluzzi, Vanessa T; Amaral, Olavo B (Cold Spring Harbor Laboratory, 2020)

  Preprint usage is growing rapidly in the life sciences; however, questions remain on the relative quality of preprints when compared to published articles. An objective dimension of quality that is readily measurable is ...

• Molecular characterization and epidemiological aspects of non-polio enteroviruses isolated from acute flaccid paralysis in Brazil: a historical series (2005–2017) 

  Sousa Júnior, Ivanildo Pedro de; Oliveira, Maria de Lourdes Aguiar; Burlandy, Fernanda M; Machado, Raiana Scerni; Oliveira, Silas S; Tavares, Fernando N; Gomes Neto, Francisco; Costa, Eliane V. da; Silva, Edson E. da (Taylor & Francis, 2020)

  Due to the advanced stage of polio eradication, the possible role of non-polio enteroviruses (NPEVs) associated to acute flaccid paralysis (AFP) cases has been highlighted. In this study, we described epidemiological aspects ...

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