• First report of an Asymptomatic Leishmania (Viannia) shawi infection using a nasal swab in Amazon, Brazil 

  Santos, Fabiola S; Oliveira, Luciana Pinto; Nascimento, Luciana de Cássia Silva do; Santos, Fabiola S; Takamatsu, Jaqueline L. C; Sanchez, Luiz R. P; Santos, Walter Souza; Santos, Lourdes Maria Garcez dos (MDPI, 2022)

  he state of Pará has recorded seven Leishmania species that cause tegumentary leishmaniasis (TL). Leishmania species induce distinct immunological responses from the host and exhibit resistance to Glucantime, the first-line ...

• Activity of alkaloids from Aspidosperma nitidum against Leishmania (Leishmania) amazonensis 

  Veiga, Andreza do Socorro Silva da; Silveira, Fernando Tobias; Silva, Edilene Oliveira da; Diniz Júnior, José Antônio Picanço; Araújo, Sanderson Corrêa; Campos, Marliane Batista; Marinho, Andrey Moacir do Rosário; Brandão, Geraldo Célio; Vale, Valdicley Vieira; Percário, Sandro; Dolabela, Maria Fâni (Nature Research, 2022)

  This study evaluated the morphological changes caused by fractions and subfractions, obtained from barks of Aspidosperna nitidum, against L. (L.) amazonensis promastigotes. The ethanolic extract (EE) obtained through the ...

• Phylogeny of Anopheles darlingi (Diptera:Culicidae) based on the antimicrobial peptide genes cecropin and defensin 

  Santos, Erian de Almeida; Santos, Ana Cecília Feio dos; Silva, Fábio Silva da; Queiroz, Alice Louize Nunes; Pires, Luciana Letícia da Costa; Casseb, Samir Mansour Moraes; Holanda, Gustavo Moraes; Sucupira, Izis Mônica Carvalho; Cruz, Ana Cecília Ribeiro; Santos, Eduardo José Melo dos; Póvoa, Marinete Marins (Elsevier, 2022)

  Cecropins and defensins are the main classes of antimicrobial peptides in the mosquito innate immune system, acting against bacteria, fungi and protozoa. There is a knowledge gap concerning these peptide genes in anopheline ...

• Molecular characterization of the gastrointestinal eukaryotic virome in elderly people in Belem, Para, Brazil 

  Portal, Thayara Morais; Vanmechelen, Bert; Van Espen, Lore; Jansen, Daan; Teixeira, Dielle Monteiro; Sousa, Emanuella Sarmento Alho de; Silva, Victor Pereira da; Lima, Juliana Silva de; Reymão, Tammy Katlhyn Amaral; Sequeira, Carina Guilhon; Ventura, Ana Maria Revorêdo da Silva; Silva, Luciana Damascena da; Resque, Hugo Reis; Metthijnssens, Jelle; Gabbay, Yvone Benchimol (Elsevier, 2022)

  Acute gastroenteritis is one of the main causes of mortality and morbidity worldwide, affecting mainly children, the immunocompromised and elderly people. Enteric viruses, especially rotavirus A, are considered important ...

• Higher-dose Primaquine to prevent relapse of Plasmodium vivax Malaria 

  Siqueira, Nathália Nogueira Chamma; Negreiros, Suiane C; Ballard, Sarah-Blythe; Farias, Sâmela; Silva, Sandro Patroca da; Chenet, Stella M; Santos, Eduardo J. M; Sena, Luann W. Pereira de; Costa, Flávio Póvoa da; Mello, Amanda Gabryelle Nunes Cardoso; Marchesini, Paola B; Peterka, Cássio R. L; Vianna, Giselle Maria Rachid; Oliveira, Alexandre Macedo de (Massachusetts Medical Society, 2022)

  BACKGROUND: In most of the Americas, the recommended treatment to prevent relapse of Plasmodium vivax malaria is primaquine at a total dose of 3.5 mg per kilogram of body weight, despite evidence of only moderate ...

• Cryptococcal meningitis in patients with and without acquired immunodeficiency 

  Ohnishi, Yumi de Oliveira; Pantoja, Antonio Saulo Leão; Abraão, Luciano Sami de Oliveira; Alves, Natália Guedes; Ohnishi, Maria Deise de Oliveira; Libonati, Rosana Maria Feio; Ventura, Ana Maria Revorêdo da Silva; Palácios, Vera Regina da Cunha Menezes (Elsevier, 2022)

• Association between vitamin D serum levels and clinical, laboratory, and parasitological parameters in patients with malaria from an endemic area of the Amazon 

  Setto, Janaina Maria; Libonati, Rosana Maria Feio; Ventura, Ana Maria Revoredo da Silva; Chaves, Tânia do Socorro Souza; Sequeira, Carina Guilhon; Martins Filho, Arnaldo Jorge; Machado, Ricardo Luiz Dantas; Franceschin, Sylvia do Carmo Castro; Barreto, Jéssica Thuanny Teixeira (Sociedade Brasileira de Medicina Tropical, 2022)

  Background: Some studies have suggested the importance of vitamin D [25(OH)D] in malaria clinical practice. The prevalence of 25(OH)D deficiency in the Amazon population is not well known, and there are few studies in ...

• Reliability of point-of-care circulating cathodic antigen assay for diagnosing schistosomiasis mansoni in urine samples from an endemic area of Brazil after one year of storage at -20 degrees Celsius 

  Favre, Tereza Cristina; Beck, Lilian Christina Nóbrega Holsback; Bezerra, Fernando Schemelzer Moraes; Teixeira, Carlos Graeff; Coelho, Paulo Marcos Zech; Enk, Martin Johannes; Katz, Naftale; Oliveira, Ricardo Riccio; Reis, Mitermayer Galvão dos; Pieri, Otávio Sarmento (Sociedade Brasileira de Medicina Tropical, 2022)

  Background: The World Health Organization recommends reliable point-of-care (POC) diagnostic testing to eliminate schistosomiasis. Lateral flow immunoassay that detects schistosome circulating cathodic antigen (CCA) in ...

• DNA damage and proteomic profile changes in rat salivary glands after chronic exposure to inorganic mercury 

  Aragão, Walessa Alana Bragança; Bittencourt, Leonardo Oliveira; Lima, Leidiane Alencar de Oliveira; Souza, Michel Platini caldas de; Nogueira, Lygia Sega; Dionizio, Aline; Buzalaf, Marília Afonso Rabelo; Oliveira, Edivaldo Herculano Corrêa de; Lopez, Maria Elena Crespo; Lima, Rafael Rodrigues (Springer Verlag, 2022)

  Mercury (Hg) is a toxic metal that became a public health problem due to environmental contamination caused by anthropogenic activity. In this sense, oral homeostasis can undergo changes due to the toxic effects of metal ...

• Behavioral and neuropathological changes after Toxoplasma gondii ocular conjunctival infection in BALB/c Mice 

  Soares, Gabrielly Lisboa da Silva; Leão, Ellen Rose Leonardo Ponce de; Freitas, Sinara Franco; Alves, Raissa Maria Carvalho; Tavares, Naiana de Paula; Costa, Maria Vitória Nascimento; Menezes, Gabriel Castro de; Oliveira, Jhonnathan Henrique Palheta de; Guerreiro, Luma Cristina Ferreira; Assis, Alexa Camila Lopes de; Araújo, Sanderson Corrêa; Franco, Felipe Tuji de Castro; Anaissi, Ana Karyssa Mendes; Carmo, Ediclei Lima do; Morais, Rafaela dos Anjos Pinheiro Bogoevich; Demachki, Samia; Diniz, José Antônio Picanço; Nunes, Heloisa Marceliano; Anthony, Daniel C; Diniz, Daniel Guerreiro; Diniz, Cristovam Wanderley Picanço (Frontiers Media, 2022)

  Ocular infection with Toxoplasma gondii causes toxoplasmosis in mice. However, following ocular infection with tachyzoites, the cause of the accompanying progressive changes in hippocampal-dependent tasks, and their ...

• Analysis of malaria clinical-epidemiological predictors in individuals from Brazilian Amazon 

  Lisboa, Paulo Guilherme Souza; Medeiros, Janaina Maria Rodrigues; Souza, Arthur Vinícius de; Santos, Bruno Fernando Barros dos; Sanches, Henrique Otavio Coutinho; Rocha, Juliane Lúcia Gomes da; Corrêa Junior, Wender de Jesus Pena; Costa, Gabriela Goes; Chaves, Tania do Socorro Souza; Ventura, Ana Maria Revoredo da Silva; Libonati, Rosana Maria Feio (Cambridge University Press, 2022)

  This research aims to determine whether the combination of epidemiological and clinical features can predict malaria. Diagnostic investigation detected 22.3% of individuals with Plasmodium vivax (P. vivax) malaria, with ...

• Whole-genome sequencing of Leishmania infantum chagasi isolates from Honduras and Brazil 

  Silveira, Fernando Tobias; Sousa Junior, Edivaldo Costa; Silvestre, Rodrigo Vellasco Duarte; Martins, André Guilherme Costa; Pinheiro, Kenny da Costa; Ochoa, Wilfredo Sosa; Santos, Thiago Vasconcelos dos; Ramos, Patrícia Karla; Casseb, Samir Mansour Moraes; Silva, Sandro Patroca da; Valeriano, Concepción Zúniga; Lima, Luciana Vieira; Campos, Marliane Batista; Matta, Vania Lucia da; Gomes, Claudia Maria; Flores, Gabriela Venicia; Pacheco, Carmen Maria; Corbett, Carlos Eduardo; Nakaya, Helder; Laurenti, Márcia Dalastra (American Society for Microbiology, 2021)

  This work reports on the whole-genome sequencing of Leishmania infantum chagasi from Honduras (Central America) and Brazil (South America).

• Mixed Plasmodium malariae infections were underdetected in a malaria endemic area in the Amazon Region, Brazil 

  Cunha, Maristela Gomes da; Santos, Camille S; Raiol, Milene; Costa, Sheyla Patrícia T; Ventura, Ana Maria Revoredo da Silva; Póvoa, Marinete Marins; Santos, Ândrea Ribeiro dos (American Society of Tropical Medicine and Hygiene, 2021)

  Plasmodium malariae infections are often asymptomatic and long-lasting. Mixed infections are often underdetected in areas where P. malariae, P. vivax, and P. falciparum are coendemic. In this study, we described the ...

• Evaluation of systemic immunity in atypical cutaneous leishmaniasis caused by Leishmania (L.) infantum chagasi 

  Laurenti, Márcia Dalastra; Sosa-Ochoa, Wilfredo; Flores, Gabriela Venicia Araújo; Pacheco, Carmen Maria Sandoval; Tomokane, Thaise Yumie; Oliveira, Luanda Mara da Silva; Zúniga, Concepción; Silveira, Fernando Tobias; Corbett, Carlos Eduardo Pereira (Wiley, 2022)

  In some central-American countries, Leishmania (L.) infantum chagasi infection can cause non-ulcerated or atypical cutaneous leishmaniasis (NUCL) in addition to the classic clinical form, visceral leishmaniasis (VL). Little ...

• Yellow fever reemergence in Venezuela – Implications for international travelers and Latin American countries during the COVID-19 pandemic 

  Morales, Alfonso J. Rodríguez; Aldana, D. Katterine Bonilla; Suárez, José Antonio; Paredes, Carlos Franco; Peña, David A. Forero; Mattar, Salim; Gómez, Wilmer E. Villamil; Sáenz, Julián Ruíz; Ospina, Jaime A. Cardona; Figuera, Manuel E; Carrero, Leandro Luis Sierra; Risquez, Alejandro; Cimerman, Sergio; Cedeño, Nereida Valero; Cabrera, Maritza; Barrios, Andrea J. Robaina; Díaz, Luis López; Barbella, Rosa; Navas, Rosa M; Quijano, Fredi Díaz; Carrero, Yenddy; Pineda, Anishmenia; Brito, Maximo O; Larriera, Eduardo Savio; Gutierrez, Marlen Martinez; Afaray, Julio Maquera; Portilla, Marco A. Solarte; Botero, Sebastián Hernández; Contreras, Krisell; López, Maria Graciela; Martinez, Andrés F. Henao; Martinez, Yeimer Ortiz; Chaves, Tânia do Socorro Souza; Orduna, Tomas; Lepetic, Alejandro; Macchi, Alejandra; Verbaanz, Sergio; Perret, Cecilia; Echazarreta, Sofía; Lloveras, Susana Cristina; Gallego, Viviana; Navarro, Juan-Carlos; Mondolfi, Alberto Paniz (Elsevier, 2021)

• Morphological description of immature stages of Trichophoromyia brachipyga (Mangabeira) (Diptera: Psychodidae: Phlebotominae) 

  Uzcátegui, Yetsenia Del Valle Sánchez; Santos, Thiago Vasconcelos dos; Póvoa, Marinete Marins (Magnolia Press, 2021)

  Trichophoromyia brachipyga (Mangabeira) (Diptera: Psychodidae: Phlebotominae) is a widely distributed species that has been recently regarded as a putative vector of Leishmania (Viannia) lainsoni Silveira, Shaw, Braga & ...

• Effects of fluoride on submandibular glands of mice: changes in oxidative biochemistry, proteomic profile, and genotoxicity 

  Lima, Leidiane Alencar de Oliveira; Miranda, Giza Hellen Nonato; Aragão, Walessa Alana Bragança; Bittencourt, Leonardo Oliveira; Santos, Sávio Monteiro dos; Souza, Michel Platini Caldas de; Nogueira, Lygia Sega; Oliveira, Edivaldo Herculano Corrêa de; Monteiro, Marta Chagas; Dionizio, Aline; Pessan, Juliano Pelim; Buzalaf, Marília Afonso Rabelo; Lima, Rafael Rodrigues (Frontiers Media, 2021)

  Although fluoride (F) is well-known to prevent dental caries, changes in cell processes in different tissues have been associated with its excessive exposure. Thus, this study aimed to evaluate the effects of F exposure ...

• Socio-epidemiological features and spatial distribution of Malaria in an area under mining activity in the Brazilian Amazon Region 

  Ueno, Thalyta Mariany Rêgo Lopes; Lima, Luana Nepomuceno Gondim Costa; Sardinha, Daniele Melo; Rodrigues, Yan Corrêa; Souza, Herberto Ueno Seelig de; Teixeira, Paula Ribeiro; Guimarães, Ricardo José de Paula Souza e; Lima, Karla Valéria Batista; Ventura, Ana Maria Revorêdo da Silva (MDPI, 2021)

  Abstract: Malaria is an acute febrile infectious disease that represents an important public health problem in the Brazilian amazon region. The present study described the socio-epidemiological and spatial characteristics ...

• Environmental influences measured by epigenetic clock and vulnerability components at birth impact clinical ASD heterogeneity 

  Reis, Viviane Neri de Souza; Tahira, Ana Carolina; Gastaldi, Vinícius Daguano; Mari, Paula; Portolese, Joana; Santos, Ana Cecilia Feio dos; Lisboa, Bianca; Mari, Jair; Caetano, Sheila C; Brunoni, Décio; Bordini, Daniela; Paula, Cristiane Silvestre de; Vêncio, Ricardo Z. N; Quackenbush, John; Brentani, Helena (MDPI, 2021)

  Although Autism Spectrum Disorders (ASD) is recognized as being heavily influenced by genetic factors, the role of epigenetic and environmental factors is still being established. This study aimed to identify ASD vulnerability ...

• The Psychodidae (Diptera) of Jail National Park (Amazonas, Brazil) with description of two new species of Psychodinae 

  Cordeiro, Danilo Pacheco; Aquino, Karina Kethelen Silva de; Alves, Veracilda Ribeiro (Magnolia Press, 2021)

  The Jaú National Park, located in the Amazon, is the largest National Park of Brazil and still its insect fauna is barely known. Herein we describe two new species of Psychodinae, Alepia iy sp. nov. and Parasetomima timmirima ...

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