• Syphilis in a mining region of the Brazilian Amazon: prevalence and characteristics 

  Ueno, Thalyta Mariany Rêgo Lopes; Gomes, Samara Tatielle Monteiro; Sousa, Maísa Silva de; Favacho, Joana da Felicidade Ribeiro; Lima, Luana Nepomuceno Gondim Costa; Sardinha, Daniele Melo; Rodrigues, Yan Corrêa; Guimarães, Ricardo José de Paula Souza e; Ventura, Ana Maria Revoredo da Silva; Lima, Karla Valéria Batista (2021)

  Syphilis is a chronic bacterial infection, being one of the main determinants of sexually transmitted infections (STIs). It is endemic in low-income countries, it is important for both individual and public health because, ...

• Antibodies against the Plasmodium vivax apical membrane antigen 1 from the Belem strain share common epitopes among other worldwide variants 

  França, Ana Caroline Barbosa; Françoso, Kátia Sanches; Marques, Rodolfo Ferreira; Trossini, Gustavo H. G; Gomes, Renan A; Póvoa, Marinete Marins; Cunha, Maristela G; Silveira, Eduardo L. V; Soares, Irene S (Frontiers Media, 2021)

  Malaria is a human parasitic disease distributed in many tropical countries and caused by various Plasmodium species. Plasmodium vivax has the largest geographical distribution of the Plasmodium species and is predominant ...

• Hepatite C na década de 1980: resgate de casos das antigas hepatites "não A e não B" de um serviço de hepatologia na Amazônia, Brasil 

  Barbosa, Kemere Marques Vieira; Moreira, Luiz Vinicius Leão; Oliveira, Candida Maria Abrahão de; Souza, Alex Junior Souza de; Nunes, Heloisa Marceliano; Soares, Manoel do Carmo Pereira; Santos, Lourdes Maria Garcez dos (MS/SVS/Instituto Evandro Chagas, 2019)

  OBJETIVO: Descrever a frequência de infecção pelo vírus da hepatite C (VHC) em amostras de soro de pacientes diagnosticados como hepatite "não-A e não-B", atendidos em um instituto de pesquisa da Amazônia, entre 1982 e ...

• In situ cellular immune response in non-ulcerated skin lesions due to Leishmania (L.) infantum chagasi infection 

  Sandoval, Carmen; Araujo, Gabriela; Sosa, Wilfredo; Avalos, Sara; Silveira, Fernando; Corbett, Carlos; Zúniga, Concepción; Laurenti, Marcia (BMC, 2021)

  Background: Skin lesions of patients affected by non-ulcerated cutaneous leishmaniasis (NUCL) caused by L. (L.) infantum chagasi are characterized by lymphohistiocytic inflammatory infiltrate associated with epithelioid ...

• Low specificity of point-of-care circulating cathodic antigen (POC[sbnd]CCA) diagnostic test in a non-endemic area for schistosomiasis mansoni in Brazil 

  Graeff-Teixeira, Carlos; Favero, Vivian; Pascoal, Vanessa Fey; Souza, Renata Perotto de; Rigo, Francine de Vargas; Agnese, Luis Hoffmann Dall; Bezerra, Fernando Schemelzer Moraes; Coelho, Paulo Marcos Zech; Enk, Martin Johannes; Favre, Tereza Cristina; Katz, Naftale; Oliveira, Ricardo Riccio; Reis, Mitermayer Galvão dos; Pieri, Otavio Sarmento (Elsevier, 2021)

  A point-of-care test for detecting schistosome circulating cathodic antigen in urine (POC[sbnd]CCA) has been proposed for mapping infection and defining prevalence thresholds for mass drug administration (MDA). However, ...

• Urine qPCR diagnoses over the entire clinical-immunological spectrum of human Leishmania (L.) infantum chagasi-infections in the Brazilian Amazon 

  Ramos, Patrícia Karla Santos; Gonçalves, Lucas Pantoja; Alves, Ana Camila Oliveira; Casseb, Samir Mansour Moraes; Lima, Luciana Vieira do Rêgo; Campos, Marliane Batista; Santos, Thiago Vasconcelos dos; Silveira, Fernando Tobias (Elsevier, 2021)

  The clinical-immunological spectrum of human Leishmania (L.) infantum chagasi-infections in the Brazilian Amazon has been defined using DTH/IFAT-IgG immune assays and the clinical statuses of infected individuals, revealing ...

• Evaluation of histidine-rich proteins 2 and 3 gene deletions in Plasmodium falciparum in endemic areas of the Brazilian Amazon 

  Góes, Leandro; Siqueira, Nathália Chamma; Peres, José Mário; Nascimento, José Maria; Valle, Suiane; Arcanjo, Ana Ruth; Lacerda, Marcus; Blume, Liana; Póvoa, Marinete Marins; Vianna, Giselle Maria Rachid (MDPI, 2021)

  Histidine-rich proteins 2 and 3 gene (pfhrp2 and pfhrp3) deletions affect the efficacy of rapid diagnostic tests (RDTs) based on the histidine-rich protein 2 (HRP2), compromising the correct identification of the Plasmodium ...

• Further insights into the eco-epidemiology of American cutaneous leishmaniasis in the Belem metropolitan region, Pará State, Brazil 

  Gonçalves, Lucas Pantoja; Santos, Thiago Vasconcelos dos; Campos, Marliane Batista; Lima, Luciana Vieira do Rêgo; Ishikawa, Edna Aoba Yassui; Silveira, Fernando Tobias; Ramos, Patrícia Karla Santos (Sociedade Brasileira de Medicina Tropical, 2020)

  Introduction: In the Belém Metropolitan Region (BMR), Pará State, Brazil, American cutaneous leishmaniasis (ACL) is endemic; however, very little is known regarding its causative agents. Therefore, we used our standard ...

• Doença de Chagas - Protocolos clínicos de seguimento pós-tratamento em grupos especiais: experiência do IEC com binômio mãe-filho 

  Pinto, Ana Yecê das Neves; Valente, Vera da Costa; Aguiar, Maria Cleonice Justino; Valente, Sebastião Aldo da Silva; Ramos, Francisco Lúzio de Paula; Santos, Edcleiton Marins; Mota, Bruna Daniele Lisboa; Viana, Giselle Maria Rachid (Ministério da Saúde. Secretaria de Vigilância em Saúde, 2020)

• First report of canine infection by leishmania (Viannia) guyanensis in the brazilian amazon 

  Santos, Francisco J. A; Nascimento, Luciana de Cássia Silva do; Silva, Wellington Bandeira da; Oliveira, Luciana P; Santos, Walter Souza; Aguiar, Délia Cristina Figueira; Santos, Lourdes Maria Garcez dos (MDPI, 2020)

  Abstract: The American cutaneous (CL) and visceral leishmaniasis (VL) are zooanthroponoses transmitted by sand flies. Brazil records thousands of human leishmaniasis cases annually. Dogs are reservoirs of Leishmania ...

• Polymorphism in the IL-1β promoter is associated with IgG antibody response to circumsporozoite protein repeats of Plasmodium vivax 

  Capobianco, Marcela Petrolini; Cassiano, Gustavo Capatti; Storti-Melo, Luciane Moreno; Pimenta, Tamirys Simão; Rodrigues, Ana Paula Drummond; Arruda, José Eduardo Gomes; Pinto, Marcia Ribeiro; Baptista, Andrea Regina de Souza; Pratt-Riccio, Lilian Rose; Bonini-Domingos, Cláudia Regina; Oliveira-Ferreira, Joseli de; Machado, Ricardo Luiz Dantas (Oxford University Press, 2020)

  BACKGROUND: It is well established that infection by Plasmodium vivax is a result of host-parasite interactions. In the present study, association with the IL1/IL2 cytokine profiles, anticircumsporozoite protein antibody ...

• Spatial analysis studies of endemic diseases for health surveillance: application of scan statistics for surveillance of tuberculosis among residents of a metropolitan municipality aged 60 years and above 

  Mesquita, Cristal Ribeiro; Enk, Martin Johannes; Guimarães, Ricardo José de Paula Souza e (Abrasco, 2020)

  Health surveillance aims to monitor adverse health events, and to set disease prevention and control goals, especially for communicable diseases, such as tuberculosis (TB).Older people have a higher risk of TB, due to their ...

• Clinical, cardiological and serologic follow-up of Chagas Disease in children and adolescents from the Amazon Region, Brazil: longitudinal study 

  Pinto, Ana Yecê das Neves; Valente, Vera da Costa; Valente, Sebastião Aldo da Silva; Motta, Tamires Anastácia Rodrigues; Ventura, Ana Maria Revorêdo da Silva (MDPI, 2020)

  Background:Outbreaks of Chagas disease (CD) by foodborne transmission is a problem related to deforestation, exposing people to triatomines infected by T. cruzi, in the Amazon region. Once involving long-time follow-up, ...

• Chronic methylmercury exposure causes spinal cord impairment: proteomic modulation and oxidative stress 

  Eiró, Luciana Guimarães; Ferreira, Maria Karolina Martins; Bittencourt, Leonardo Oliveira; Aragão, Walessa Alana Bragança; Souza, Michel Platini Caldas de; Silva, Marcia Cristina Freitas; Dionizio, Aline; Buzalaf, Marília Afonso Rabelo; Crespo-López, Maria Elena; Lima, Rafael Rodrigues (Elsevier, 2020)

  Methylmercury (MeHg) is considered by the World Health Organization (WHO) as one of the chemicals of greatest public health concern. Although central nervous system (CNS) is the main target organ, the effects over the ...

• The use of the circulating cathodic antigen (Cca) urine cassette assay for the diagnosis and assessment of cure of schistosoma mansoni infections in an endemic 

  Sousa, Sergei Rodrigo Magalhães de; Nogueira, Joyce Favacho Cardoso; Dias, Isabelle Helena Lima; Fonseca, Álvaro Luan Santana; Favero, Vivian; Geiger, Stefan Michael; Enk, Martin Johannes (Sociedade Brasileira de Medicina Tropical, 2020)

  INTRODUCTION: Schistosomiasis is a poverty-related disease that affects people in 78 countries worldwide. This study aimed to evaluate the point-of-care circulating cathodic antigen (POC-CCA) test performance using sensitive ...

• Clinical-epidemiological analysis of the care services at a special immunobiological reference center in the amazon 

  Espindola, Paula Rachel Neves; Soares, Gabrielly Lisboa da Silva; Pereira, Elizabeth do Socorro Pantoja; Oliveira, Kárila Larissa Pereira de; Brito, Jaira Ataide dos Santos de; Hora, Dinair Leal da; Chaves, Tânia do Socorro Souza (Universidade Federal do Paraná. Departamento de Enfermagem, 2020)

  Objective: to describe the clinical-epidemiological profile of the care service at the Reference Center for Special Immunobiologicals of Hospital in the Amazon. Method: a descriptive study, of a quantitative approach and ...

• Reactivity of purified and axenic amastigotes as a source of antigens to be used in serodiagnosis of canine visceral leishmaniasis 

  Silva, Thais Bruna Ferreira da; Silveira, Fernando Tobias; Tomokane, Thaise Yumie; Batista, Luis Fábio da Silva; Nunes, Juliana Barbosa; Matta, Vânia Lúcia Ribeiro da; Passero, Luiz Felipe Domingues; Laurenti, Márcia Dalastra (Elsevier, 2020)

  Although there is a great diversity of techniques and antigens used in the serodiagnosis of canine visceral leishmaniasis (CVL), total sensitivity and specificity have not yet been found. Since the use of amastigote forms ...

• Accuracy of real-time polymerase chain reaction to detect Schistosoma mansoni – infected individuals from an endemic area with low parasite loads 

  Magalhães, Fernanda do Carmo; Resende, Samira Diniz; Senra, Carolina; Graeff-Teixeira, Carlos; Enk, Martin Johannes; Coelho, Paulo Marcos Zech; Oliveira, Edward; Corrêa, Deborah Aparecida Negrão; Geiger, Stefan Michael; Carneiro, Mariângela (Cambridge University Press, 2020)

  Due to the efforts to control schistosomiasis transmission in tropical countries, a large proportion of individuals from endemic areas present low parasite loads, which hinders diagnosis of intestinal schistosomiasis by ...

• Association of cerebral malaria and TNF-alpha levels: a systematic review 

  Leão, Luana; Puty, Bruna; Dolabela, Maria Fâni; Povoa, Marinete Marins; Né, Yago Gecy de Sousa; Eiró, Luciana Guimarães; Fagundes, Nathália Carolina Fernandes; Maia, Lucianne Cople; Lima, Rafael Rodrigues (BMC, 2020)

  Background: Cerebral malaria is the most severe form of infection with Plasmodium falciparum characterized by a highly inflammatory response. This systematic review aimed to investigate the association between TNF-α ...

• Clinical and immunological features of human Leishmania (L.) infantum-Infection, novel insights Honduras, Central America 

  Sosa-Ochoa, Wilfredo; Zúniga, Concepción; Chaves, Luis Fernando; Flores, Gabriela Venicia Araújo; Pacheco, Carmen Maria Sandoval; Matta, Vania Lúcia Ribeiro da; Corbett, Carlos Eduardo Pereira; Silveira, Fernando Tobias; Laurenti, Marcia Dalastra (MDPI, 2020)

  Leishmania (Leishmania) infantum is the etiological agent of both American visceral leishmaniasis (AVL) and non-ulcerated cutaneous leishmaniasis (NUCL) in Honduras. Although AVL is the most severe clinical form of ...

View more