• Caracterização do vírus Oropouche (BeAn 19991). Contribuição ao estudo ultra-estrutural da infecção experimental 

      Araujo, Ronaldo de; Araujo, Marialva T. F; Pinheiro Filho, Francisco de Paula; Dias, Leônidas Braga; Cruz, Ermelinda M (Universidade Federal do Pará, 1980)
      São poucos numerosas as partículas do vírus Oropouche (BeAn 1999) nos tecidos de animais inoculados experimentalmente: a pesquisa cuidadosa em cortes de cérebro de vinte animais inoculados experimentalmente (2 camundongos ...
    • A case of yellow fever in a brown howler (Alouatta fusca) in Southern Brazil 

      Sallis, Eliza Simone Viégas; Barros, Vera Lúcia Reis de Souza; Garmatz, Shana Letícia; Fighera, Rafael Almeida; Graça, Dominguita Lühers (SAGE Publications, 2003)
      Many brown howlers (Alouatta fusca) have died in a 3-month period in a subtropical forest in Southern Brazil. One was examined after a systemic illness. According to clinical signs, and necropsy and histopathology findings, ...
    • Clinical and immunological profiles of anaemia in children and adolescents with Plasmodium vivax malaria in the Pará state, Brazilian Amazon 

      Ventura, Ana Maria Revoredo da Silva; Fernandes, Andrea Aparecida Moraes; Zanini, Graziela Maria; Pratt-Riccio, Lilian Rose; Sequeira, Carina Guilhon; Monte, Carlos Rodrigo Souza do; Martins Filho, Arnaldo Jorge; Machado, Ricardo Luiz Dantas; Libonati, Rosana Maria Feio; Souza, José Maria de; Daniel-Ribeiro, Cláudio Tadeu (Elsevier, 2018)
      Children and adolescents are at great risk for developing iron deficiency anaemia worldwide. In the tropical areas, malaria and intestinal parasites may also play an important role in anaemia pathogenesis. This study aimed ...
    • Correlation between apoptosis and in situ immune response in fatal cases of microcephaly caused by Zika Virus 

      Sousa, Jorge R. de; Azevedo, Raimunda do Socorro da Silva; Martins Filho, Arnaldo Jorge; Araújo, Marialva T. F; Moutinho, Ermelinda R. C; Vasconcelos, Barbara C. Baldez; Cruz, Ana Cecília Ribeiro; Oliveira, Consuelo Silva de; Martins, Lívia Carício; Vasconcelos, Beatriz H. Baldez; Casseb, Livia Medeiros Neves; Chiang, Jannifer Oliveira; Quaresma, Juarez Antônio Simões; Vasconcelos, Pedro Fernando da Costa (Elsevier, 2018)
      Zika virus (ZIKV) is a single-stranded positive-sense RNA flavivirus that possesses a genome approximately 10.7 Kb in length. Although pro-inflammatory and anti-inflammatory cytokines and apoptotic markers belonging to the ...
    • Dermatoses por helmintos 

      Moares, Mário Augusto Pinto de (Eleá Ciência Editorial, 1974)
    • Doppler ultrasonography: a non-invasive method used to diagnose and follow up patients with chronic hepatitis C 

      Franco, Karen Margarete Vieira da Silva; Vieira, Waldonio Brito; Dias, Apio Ricardo Nazareth; Falcão, Aline Semblano Carreira; Falcão, Luiz Fábio Magno; Quaresma, Juarez Antônio Simões (Wiley, 2020)
      Background and Aim: This study aimed to investigate the association between the findings of Doppler ultrasonography and transient elastography using FibroScan and to determine the cut-off points, sensitivity, and specificity ...
    • Endoplasmic reticulum stress markers and their possible implications in leprosy's pathogenesis 

      Hirai, Kelly Emi; Sousa, Jorge Rodrigues de; Silva, Luciana Mota; Dias Junior, Leônidas Braga; Furlaneto, Ismari Perini; Carneiro, Francisca Regina Oliveira; Aarão, Tinara Leila de Souza; Sotto, Mirian Nacagami; Quaresma, Juarez Antonio Simões (Hindawi Publishing Corporation, 2018)
      Mycobacterium leprae causes leprosy, a dermatoneurological disease which affects the skin and peripheral nerves. One of several cellular structures affected during M. leprae infection is the endoplasmic reticulum (ER). ...
    • Estado atual do conhecimento sobre os focos brasileiros de oncocercose 

      Moraes, Mário Augusto Pinto de; Shelley, Anthony J; Calheiros, Lélio B; Porto, Marcos A. S (Sociedade Brasileira de Dermatologia, 1979)
    • Estudo experimental sobre a patogenicidade do Vírus Ilhéus em hamsters dourados (Mesocricetus auratus) 

      Azevedo, Raimunda do Socorro da Silva; Barros, Vera Lúcia Reis de Souza; Matins, Lívia Caricio; Cruz, Ana Cecília Ribeiro; Rodrigues, Sueli Guerreiro; Vasconcelos, Pedro Fernando da Costa (Instituto Evandro Chagas, 2010)
      Visando investigar a patogenicidade do Flavivirus Ilhéus (VILH) foi inoculada, via intraperitoneal, 9,8 DL de suspensão 50 viral em hamsters dourados jovens (Mesocricetus auratus) e, diariamente, soros e vísceras (cérebro, ...
    • Estudo piloto: análise do fígado de ratos submetidos ao alcoolismo crônico experimental e tratados com Morinda citrifolia (noni) 

      Monma, Cristiane Akina; Silva, Naiara Nascimento; Neotti, Tatiane; Coutinho, Victor Augusto Grécia; Brito, Rosângela Baía; Domingues, Robson José de Souza; Ribeiro, Nelson Antonio Bailão (Instituto Evandro Chagas, 2015)
      O etilismo crônico causa dano hepático sequencial, desde esteato-hepatite até cirrose e então doença hepática em estágio final. A reparação hepática torna-se comprometida por aumento do estresse oxidativo, danos no DNA, ...
    • Experimental infection of golden hamsters with Guama virus (Peribunyaviridae, Orthobunyavirus) 

      Matos, Gabriel Costa; Ferreira, Milene Silveira; Martins Filho, Arnaldo Jorge; Amador Neto, Orlando Pereira; Campos, Valter Miranda; Lima, Maria de Lourdes Gomes de; Rodrigues, Jéssica Cecília Pinheiro; Ribeiro, Ana Claudia da Silva; Freitas, Maria de Nazaré Oliveira; Silva, Franko de Arruda e; Chiang, Jannifer Oliveira; Casseb, Livia Medeiros Neves; Sousa, Jorge Rodrigues de; Quaresma, Juarez Antônio Simões; Martins, Lívia Carício; Vasconcelos, Pedro Fernando da Costa; Carvalho, Valéria Lima (Elsevier, 2019)
      The Guama virus (GMAV) is a member of Peribunyaviridae family, Orthobunyavirus genus. Several strains of the virus were isolated in South and Central Americas from several hosts, such as humans, wild animals, including nonhuman ...
    • Experimental infection of Jorge Lôbo's disease in the cheek-pouch of the golden hamster (Mesocricetus Auratus) 

      Sampaio, Mário Machado; Dias, Leônidas Braga (Universidade de São Paulo, 1970)
      O agente etiológico da Doença de Jorge Lôbo inoculado na bôlsa jugal de 22 hamsters (Mesocricetus auratus) produziu nódulos de 1,5 a 5 mm de diâmetro constituídos de histiócitos e células gigantes contendo parasitas. As ...
    • First isolation of West Nile virus in Brazil 

      Martins, Lívia Caricio; Silva, Eliana Vieira Pinto da; Casseb, Livia Medeiros Neves; Silva, Sandro Patroca da; Cruz, Ana Cecília Ribeiro; Pantoja, Jamilla Augusto de Sousa; Medeiros, Daniele Barbosa de Almeida; Martins Filho, Arnaldo Jorge; Cruz, Ermelinda do Rosário Moutinho da; Araújo, Marialva Tereza Ferreira de; Cardoso, Jedson Ferreira; Cunha, Marcos Antônio Correia da; Almada, Gilton Luiz; Romano, Alessandro Pecego Martins; Santos, Maria Guadalupe Dias Pestana; Rodrigues, Gilsa Aparecida Pimenta; Chiang, Jannifer Oliveira; Quaresma, Juarez Antonio Simões; Carvalho, Valéria Lima; Vasconcelos, Pedro Fernando da Costa (Instituto Oswaldo Cruz, 2019)
      BACKGROUND Serological evidence of West Nile virus (WNV) infection has been reported in different regions of Brazil from equine and human hosts but the virus had never been isolated in the country. OBJECTIVES We sought ...
    • Functional aspects, phenotypic heterogeneity, and tissue immune response of macrophages in infectious diseases 

      Sousa, Jorge Rodrigues de; Vasconcelos, Pedro Fernando da Costa; Quaresma, Juarez Antônio Simões (Dove Medical Press, 2019)
      Macrophages are a functionally heterogeneous group of cells with specialized functions depending not only on their subgroup but also on the function of the organ or tissue in which the cells are located. The concept of ...
    • Histopathological lesions of congenital Zika syndrome in newborn squirrel monkeys 

      Alcantara, Bianca Nascimento de; Imbeloni, Aline Amaral; Durans, Darlene de Brito Simith; Araújo, Marialva Tereza Ferreira de; Cruz, Ermelinda do Rosário Moutinho da; Carvalho, Carlos Alberto Marques de; Mendonça, Maria Helena Rodrigues de; Sousa, Jorge Rodrigues de; Moraes, Adriana Freitas; Martins Filho, Arnaldo Jorge; Lima, Maria de Lourdes Gomes; Amador Neto, Orlando Pereira; Chiang, Jannifer Oliveira; Scalercio, Sarah Raphaella Rocha de Azevedo; Carneiro, Liliane Almeida; Quaresma, Juarez Antônio Simões; Vasconcelos, Pedro Fernando da Costa; Medeiros, Daniele Barbosa de Almeida (Nature Research, 2021)
      The absence of an adequate animal model for studies has limited the understanding of congenital Zika syndrome (CZS) in humans during the outbreak in America. In this study, we used squirrel monkeys (Saimiri collinsi), a ...
    • HTLV-I induces lesions in the pulmonary system: a systematic review 

      Normando, Valéria Marques Ferreira; Dias, Ápio Ricardo Nazareth; Silva, André Luiz Saldanha Eremita da; Pinto, Denise da Silva; Santos, Marcio Clementino de Souza; Rodrigues, Caroline Lobato; Oliveira, Ediléa Monteiro de; Souza Filho, Luiz Euclides Coelho de; Vieira, Waldônio de Brito; Andriolo, Regis Bruni; Sousa, Rita Catarina Medeiros; Falcão, Luiz Fábio Magno; Quaresma, Juarez Antônio Simões (Elsevier, 2020)
      This study analyzed the relationship between infection by human T-cell lymphotropic virus type 1 (HTLV-1) and changes in the pulmonary system. Cohort and case-control study models that analyzed a causal association between ...
    • Immunohistochemical characterization of the M4 macrophage population in leprosy skin lesions 

      Sousa, Jorge Rodrigues de; Lucena Neto, Francisco Dias; Sotto, Mirian Nacagami; Quaresma, Juarez Antonio Simões (BMC, 2018)
      Background: Since macrophages are one of the major cell types involved in the Mycobacterium leprae immune response, roles of the M1 and M2 macrophage subpopulations have been well defined. However, the role of M4 macrophages ...
    • Importância dos citolisomas na gênese lesional das infecções a virus. Contribuição do estudo ultra-estrutural da infecção experimental de camundongos albinos com o virus Àgua Preta (BeAn 67949) 

      Araujo, Ronaldo de; Araujo, Marialva T. F; Pinheiro Filho, Francisco de Paula; Dias, Leônidas Braga (Universidade Federal do Pará, 1980)
      Durante a evolução lesional da infecção experimental por virus A'gua Preta (BeAn67949) foram encontradas estruturas do tipo dos citolisomas ou corpos densos que exibem partículas viróticas de variada estrutura. Esta variação ...
    • In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus 

      Azevedo, Raimunda do Socorro da Silva; Sousa, Jorge R. de; Araújo, Marialva Tereza Ferreira de; Martins Filho, Arnaldo J; Alcantara, Bianca Nascimento de; Araujo, Fernanda M. C; Queiroz, Maria G. L.; Cruz, Ana Cecília Ribeiro; Vasconcelos, Beatriz H Baldez; Chiang, Jannifer Oliveira; Martins, Lívia Caricio; Casseb, Livia Medeiros Neves; Silva, Eliana Vieira Pinto da; Carvalho, Valéria Lima; Vasconcelos, Barbara C. Baldez; Rodrigues, Sueli Guerreiro; Oliveira, Consuelo Silva de; Quaresma, Juarez A. S; Vasconcelos, Pedro Fernando da Costa (Nature Publishing Group, 2018)
      Zika virus (ZIKV) has recently caused a pandemic disease, and many cases of ZIKV infection in pregnant women resulted in abortion, stillbirth, deaths and congenital defects including microcephaly, which now has been ...
    • In situ inflammasome activation results in severe damage to the central nervous system in fatal Zika virus microcephaly cases 

      Sousa, Jorge Rodrigues de; Azevedo, Raimunda do Socorro da Silva; Martins Filho, Arnaldo Jorge; Araújo, Marialva Tereza Ferreira de; Cruz, Ermelinda do Rosário Moutinho; Vasconcelos, Barbara Cristina Baldez; Cruz, Ana Cecília Ribeiro; Oliveira, Consuelo Silva de; Martins, Livia Carício; Vasconcelos, Beatriz Helena Baldez; Casseb, Livia Medeiros Neves; Chiang, Jannifer Oliveira; Quaresma, Juarez Antonio Simões; Vasconcelos, Pedro Fernando da Costa (Elsevier, 2018)
      Zika virus (ZIKV) has caused substantial concern worldwide owing to its association with severe birth defects, such as microcephaly and other congenital malformations. Inflammasomes, i.e., multi-protein complexes that ...