• First isolation of West Nile virus in Brazil 

      Martins, Lívia Caricio; Silva, Eliana Vieira Pinto da; Casseb, Livia Medeiros Neves; Silva, Sandro Patroca da; Cruz, Ana Cecília Ribeiro; Pantoja, Jamilla Augusto de Sousa; Medeiros, Daniele Barbosa de Almeida; Martins Filho, Arnaldo Jorge; Cruz, Ermelinda do Rosário Moutinho da; Araújo, Marialva Tereza Ferreira de; Cardoso, Jedson Ferreira; Cunha, Marcos Antônio Correia da; Almada, Gilton Luiz; Romano, Alessandro Pecego Martins; Santos, Maria Guadalupe Dias Pestana; Rodrigues, Gilsa Aparecida Pimenta; Chiang, Jannifer Oliveira; Quaresma, Juarez Antonio Simões; Carvalho, Valéria Lima; Vasconcelos, Pedro Fernando da Costa (Instituto Oswaldo Cruz, 2019)
      BACKGROUND Serological evidence of West Nile virus (WNV) infection has been reported in different regions of Brazil from equine and human hosts but the virus had never been isolated in the country. OBJECTIVES We sought ...
    • Histopathological lesions of congenital Zika syndrome in newborn squirrel monkeys 

      Alcantara, Bianca Nascimento de; Imbeloni, Aline Amaral; Durans, Darlene de Brito Simith; Araújo, Marialva Tereza Ferreira de; Cruz, Ermelinda do Rosário Moutinho da; Carvalho, Carlos Alberto Marques de; Mendonça, Maria Helena Rodrigues de; Sousa, Jorge Rodrigues de; Moraes, Adriana Freitas; Martins Filho, Arnaldo Jorge; Lima, Maria de Lourdes Gomes; Amador Neto, Orlando Pereira; Chiang, Jannifer Oliveira; Scalercio, Sarah Raphaella Rocha de Azevedo; Carneiro, Liliane Almeida; Quaresma, Juarez Antônio Simões; Vasconcelos, Pedro Fernando da Costa; Medeiros, Daniele Barbosa de Almeida (Nature Research, 2021)
      The absence of an adequate animal model for studies has limited the understanding of congenital Zika syndrome (CZS) in humans during the outbreak in America. In this study, we used squirrel monkeys (Saimiri collinsi), a ...
    • In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus 

      Azevedo, Raimunda do Socorro da Silva; Sousa, Jorge R. de; Araújo, Marialva Tereza Ferreira de; Martins Filho, Arnaldo J; Alcantara, Bianca Nascimento de; Araujo, Fernanda M. C; Queiroz, Maria G. L.; Cruz, Ana Cecília Ribeiro; Vasconcelos, Beatriz H Baldez; Chiang, Jannifer Oliveira; Martins, Lívia Caricio; Casseb, Livia Medeiros Neves; Silva, Eliana Vieira Pinto da; Carvalho, Valéria Lima; Vasconcelos, Barbara C. Baldez; Rodrigues, Sueli Guerreiro; Oliveira, Consuelo Silva de; Quaresma, Juarez A. S; Vasconcelos, Pedro Fernando da Costa (Nature Publishing Group, 2018)
      Zika virus (ZIKV) has recently caused a pandemic disease, and many cases of ZIKV infection in pregnant women resulted in abortion, stillbirth, deaths and congenital defects including microcephaly, which now has been ...
    • In situ inflammasome activation results in severe damage to the central nervous system in fatal Zika virus microcephaly cases 

      Sousa, Jorge Rodrigues de; Azevedo, Raimunda do Socorro da Silva; Martins Filho, Arnaldo Jorge; Araújo, Marialva Tereza Ferreira de; Cruz, Ermelinda do Rosário Moutinho; Vasconcelos, Barbara Cristina Baldez; Cruz, Ana Cecília Ribeiro; Oliveira, Consuelo Silva de; Martins, Livia Carício; Vasconcelos, Beatriz Helena Baldez; Casseb, Livia Medeiros Neves; Chiang, Jannifer Oliveira; Quaresma, Juarez Antonio Simões; Vasconcelos, Pedro Fernando da Costa (Elsevier, 2018)
      Zika virus (ZIKV) has caused substantial concern worldwide owing to its association with severe birth defects, such as microcephaly and other congenital malformations. Inflammasomes, i.e., multi-protein complexes that ...