• Correlation between apoptosis and in situ immune response in fatal cases of microcephaly caused by Zika Virus 

      Sousa, Jorge Rodrigues de; Azevedo, Raimunda do Socorro da Silva; Martins Filho, Arnaldo Jorge; Araújo, Marialva Tereza Ferreira de; Cruz, Ermelinda do Rosário Moutinho da; Vasconcelos, Barbara Cristina Baldez; Cruz, Ana Cecília Ribeiro; Oliveira, Consuelo Silva de; Martins, Lívia Caricio; Vasconcelos, Beatriz Helena Baldez; Casseb, Lívia Medeiros Neves; Chiang, Jannifer Oliveira; Quaresma, Juarez Antônio Simões; Vasconcelos, Pedro Fernando da Costa (Elsevier, 2018)
      Zika virus (ZIKV) is a single-stranded positive-sense RNA flavivirus that possesses a genome approximately 10.7 Kb in length. Although pro-inflammatory and anti-inflammatory cytokines and apoptotic markers belonging to the ...
    • In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus 

      Azevedo, Raimunda do Socorro da Silva; Sousa, Jorge Rodrigues de; Araújo, Marialva Tereza Ferreira de; Martins Filho, Arnaldo Jorge; Alcantara, Bianca Nascimento de; Araujo, Fernanda M. C; Queiroz, Maria Goretti Lins de; Cruz, Ana Cecília Ribeiro; Vasconcelos, Beatriz Helena Baldez; Chiang, Jannifer Oliveira; Martins, Lívia Caricio; Casseb, Lívia Medeiros Neves; Silva, Eliana Vieira Pinto da; Carvalho, Valéria Lima; Vasconcelos, Barbara Cristina Baldez; Rodrigues, Sueli Guerreiro; Oliveira, Consuelo Silva de; Quaresma, Juarez Antônio Simões; Vasconcelos, Pedro Fernando da Costa (Nature Publishing Group, 2018)
      Zika virus (ZIKV) has recently caused a pandemic disease, and many cases of ZIKV infection in pregnant women resulted in abortion, stillbirth, deaths and congenital defects including microcephaly, which now has been proposed ...
    • In situ inflammasome activation results in severe damage to the central nervous system in fatal Zika virus microcephaly cases 

      Sousa, Jorge Rodrigues de; Azevedo, Raimunda do Socorro da Silva; Martins Filho, Arnaldo Jorge; Araújo, Marialva Tereza Ferreira de; Cruz, Ermelinda do Rosário Moutinho; Vasconcelos, Barbara Cristina Baldez; Cruz, Ana Cecília Ribeiro; Oliveira, Consuelo Silva de; Martins, Lívia Caricio; Vasconcelos, Beatriz Helena Baldez; Casseb, Lívia Medeiros Neves; Chiang, Jannifer Oliveira; Quaresma, Juarez Antônio Simões; Vasconcelos, Pedro Fernando da Costa (Elsevier, 2018)
      Zika virus (ZIKV) has caused substantial concern worldwide owing to its association with severe birth defects, such as microcephaly and other congenital malformations. Inflammasomes, i.e., multi-protein complexes that ...