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    • Jatobal virus antigenic characterization by ELISA and neutralization test using EIA as indicator, on tissue culture 

      Figueiredo, Luiz Tadeu M; Rosa, Amélia Paes de Andrade Travassos da (Instituto Oswaldo Cruz, 1988)
      A virus antigenic characterization methodology using an indirect method of antibody detection ELlSA with virus-infected cultured cells as antigen and a micro virus neutralisation test using E/A (NT-EIA) as an aid to reading ...

    • Linfoma de Hodgkin : aspectos epidemiológicos e subtipos diagnosticados em um hospital de referência no Estado do Pará, Brasil 

      Monteiro, Talita Antônia Furtado; Arnaud, Maria Vanda Catão; Monteiro, José Luiz Furtado; Costa, Marcos Rogério Menezes da; Vasconcelos, Pedro Fernando da Costa (Instituto Evandro Chagas, 2016)
      Os linfomas são neoplasias do sistema imunitário com origem em linfócitos B, T ou células natural killer que envolvem os tecidos linfoides que estão associados ao crescimento de massas tumorais. O linfoma de Hodgkin (LH) ...

    • Longitudinal study of rotavirus infections among children from Belém, Brazil 

      Linhares, Alexandre da Costa; Gabbay, Yvone Benchimol; Freitas, Ronaldo Barros de; Rosa, Elizabeth Salbé Travassos da; Mascarenhas, Joana D'Arc Pereira (Cambridge University Press, 1989)
      From December 1982 to March 1986 a group of 80 children between O and 3years old who lived in the peripheral area of Belém, Brazil, were followed up for episodes of diarrhoea. A total of 441 diarrhoeal episodes were ...

    • Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil 

      Silvestre, Rodrigo Vellasco Duarte; Leal, Mariana Ferreira; Demachki, Samia; Nahum, Márcia Cristina de Souza; Bernardes, Julio Guilherme Balieiro; Rabenhorst, Silvia Helena Barem; Smith, Marília de Arruda Cardoso; Mello, Wyller Alencar de; Guimarães, Adriana Costa; Burbano, Rommel Rodríguez (Instituto Oswaldo Cruz, 2009)
      The presence of human papillomavirus (HPV) was evaluated in 65 samples of prostate tumours and six samples of prostates with benign prostatic hyperplasia from individuals from Northern Brazil. We used a highly sensitive ...

    • Low genetic diversity of the Human T-cell Lymphotropic Virus (HTLV-1) in an endemic area of the Brazilian Amazon basin 

      Nobre, Akim Felipe Santos; Almeida, Danilo de Souza; Ferreira, Louise Canto; Ferreira, Deimy Lima; Sousa Júnior, Edivaldo Costa; Viana, Maria de Nazaré do Socorro de Almeida; Silva, Ingrid Christiane; Pinheiro, Bruna Teles; Ferrari, Stephen Francis; Linhares, Alexandre da Costa; Ishikawa, Edna Aoba Yassui; Sousa, Rita Catarina Medeiros de; Sousa, Maisa Silvia de (Public Library of Science, 2018)
      The Human T-cell Lymphotropic Virus (HTLV-1) is a Deltaretrovírus that was first isolated in the 1970s, and associated with Adult T-cell Leucemia-Lymphoma (ATLL), and subsequently to Tropical Spastic Paraparesis-Myelopathy ...

    • Low prevalence of human pegivirus 1 (HPgV-1) in HTLV-1 carriers from Belém, Pará, North Region of Brazil 

      Lima, Ana Beatriz Figueiredo de; Sá, Keyla Santos Guedes de; Torres, Maria Karoliny da Silva; Soares, Luana da Silva; Resques, Hugo Reis; Azevedo, Vânia Nakauth; Feitosa, Rosimar Neris Martins; Monteiro, Jacqueline Cortinhas; Silva, Andrea Nazaré Monteiro Rangel da; Ribeiro, Andre Luis Ribeiro; Oliveira-Filho, Aldemir Branco de; Vallinoto, Antonio Carlos Rosario; Machado, Luiz Fernando Almeida (Public Library of Science, 2020)
      Introduction - Human pegivirus 1 (HPgV-1) is a single-stranded, positive-sense RNA virus belonging to the Flaviviridae family with limited cause-effect evidence of the causation of human diseases. However, studies have ...

    • Measles vaccine reactions in a virgin population 

      Black, Francis Lee; Woodall, John P; Pinheiro Filho, Francisco de Paula (Oxford University Press, 1969)
      Indians of an Amazon tribe, virgin with respect to measles, have been vaccinated with the Schwartz strain of attenuated measles virus. The average of the maximum observed temperatures during the period of vaccine reaction ...

    • Medicina tradicional e populações da Amazônia: realidades das políticas de saúde 

      Castro, Nádile Juliane Costa de; Santos, Antônio Luis Parlandin dos; Miranda, Shirley Aviz de; Silva, Thais do Socorro da Luz; Naka, Karytta Sousa; Mesquita, Deisiane da Silva; Miranda, Max José de Aviz; Cordeiro, Juliana Pereira Pinto; Castro, Juliana Costa de; Santos, Dayanne de Nazaré dos (2019)
      Objetivo: Revisar na literatura a respeito das políticas de saúde direcionadas a medicina tradicional em um município paraense. Métodos: Estudo de abordagem exploratória e descritiva, com caráter documental. Como aporte ...

    • Meningite associada à infecções por vírus Oropouche 

      Pinheiro, Francisco de Paula; Rocha, Arnaldo G; Freitas, Ronaldo B; Oliana, Benjamin A; Rosa, Amélia Paes de Andrade Travassos da; Rogério, Juvenal S; Linhares, Alexandre da Costa (MS/Fundação Serviço de Saúde Pública, 1982)

    • Meningite associada ás infecções por vírus Oropouche 

      Pinheiro, Francisco de Paula; Rocha, Arnaldo G; Freitas, Ronaldo Barros de; Ohana, Benjamin A; Rosa, Amélia Paes de Andrade Travassos da; Rogério, Juvenal S; Linhares, Alexandre da Costa (Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo, 1982)
      Manifestações neurológicas associadas com infecções provocadas pelo virus Oropouche foram observadas durante o surto de 1980, no Estado do Pará. Tais manifestações consistiram em meningite ou meningismo, e foram observadas ...

    • Microssurtos familiares de gastroenterite aguda associada a rotavírus na área de Belém, Pará 

      Silva, Karla Tereza F e; Linhares, Alexandre da Costa; Gabbay, Yvone Benchimol (Fundação Serviço de Saúde Pública, 1984)
      Estudos foram realizados em 6 famílias residentes na área de Belém-Pará, Brasil, acometidas de diarréia aguda. As taxas de ataque clínico variaram de 25,0% a 71,4%, ocorrendo diarréia, mais freqüentemente, entre as crianças. ...

    • Molecular analysis of norovirus in specimens from children enrolled in a 1982-1986 study in Belém, Brazil: a community-based longitudinal study 

      Siqueira, Jones Anderson Monteiro; Sousa Júnior, Edivaldo Costa; Linhares, Alexandre da Costa; Gabbay, Yvone Benchimol (Wiley, 2017)
      Fecal specimens were collected during a longitudinal, community-based study in the city of Belém, North Brazil, that was conducted over 3 years (October 1982 to March 1986), in which 20 children were included from birth ...

    • Molecular analysis of VP4, VP7, and NSP4 genes of P[6]G2 rotavirus genotype strains recovered from neonates admitted to hospital in Belém, Brazil 

      Mascarenhas, Joana D'Arc Pereira; Linhares, Alexandre da Costa; Bayma, Amanda Patricia G; Lima, Jackson C; Sousa, Maisa S; Araújo, Irene T; Heinemann, Marcos B; Gusmão, Rosa Helena Porto; Gabbay, Yvone Benchimol; Leite, José Paulo G (Wiley, 2006)
      This investigation describes the molecular characterization of P[6] G2 rotavirus strains from hospitalized neonates with community-acquired diarrhea (CAD), nosocomial diarrhea (ND), and asymptomatic nosocomial infection ...

    • Molecular characterization and epidemiological aspects of non-polio enteroviruses isolated from acute flaccid paralysis in Brazil: a historical series (2005–2017) 

      Sousa Júnior, Ivanildo Pedro de; Oliveira, Maria de Lourdes Aguiar; Burlandy, Fernanda M; Machado, Raiana Scerni; Oliveira, Silas S; Tavares, Fernando N; Gomes Neto, Francisco; Costa, Eliane V. da; Silva, Edson E. da (Taylor & Francis, 2020)
      Due to the advanced stage of polio eradication, the possible role of non-polio enteroviruses (NPEVs) associated to acute flaccid paralysis (AFP) cases has been highlighted. In this study, we described epidemiological aspects ...

    • Molecular characterization of G1 human rotaviruses detected in children from Belém, Pará, Brazil 

      Soares, Luana da Silva; Mascarenhas, Joana D'Arc Pereira; Gabbay, Yvone Benchimol; Gusmão, Rosa Helena Porto; Linhares, Alexandre da Costa (Instituto Evandro Chagas, 2010)
      Os rotavírus são responsáveis por 40% das ocorrências de gastroenterites infantil no mundo, resultando em 611 mil mortes anualmente, e o rotavírus do tipo G1 representa o seu genótipo circulante mais comum. O objetivo do ...

    • Molecular characterization of norovirus, sapovirus and astrovirus in children with acute gastroenteritis from Belém, Pará, Brazil 

      Aragão, Glicélia Cruz; Oliveira, Darleise de Souza; Santos, Mirleide Cordeiro dos; Mascarenhas, Joana D'Arc Pereira; Oliveira, Consuelo Silva de; Linhares, Alexandre da Costa; Gabbay, Yvone Benchimol (Instituto Evandro Chagas, 2010)
      A importância dos norovírus (NoVs), sapovírus (SaVs) e astrovírus humanos (HAstVs) como causa de surtos de gastrenterites já está bem definida. Entretanto, poucos estudos têm descrito casos esporádicos de gastrenterite ...

    • Molecular characterization of TP53 gene in human populations exposed to low-dose Ionizing radiation 

      Costa, Igor Brasil; Alencar, Dayse Oliveira de; Moraes, Milene Raiol; Pessoa, Igor A; Brito, Alexandre W. M; Jati, Schneyder R; Santos, Sidney E. B; Burbano, Rommel M. R; Santos, Ândrea K. C. Ribeiro dos (Hindawi Publishing Corporation, 2013)
      Ionizing radiation, such as that emitted by uranium, may cause mutations and consequently lead to neoplasia in human cells. The TP53 gene acts to maintain genomic integrity and constitutes an important biomarker of ...

    • Molecular characterization of VP4 and NSP4 genes from rotavirus strains infecting neonates and young children in Belém, Brazil 

      Mascarenhas, Joana D'Arc Pereira; Linhares, Alexandre da Costa; Gabbay, Yvone Benchimol; Lima, Clarissa S; Guerra, Sylvia de Fátima dos Santos; Soares, Luana da Silva; Oliveira, Darleise de Souza; Lima, Jackson C; Macêdo, Olinda; Leite, José Paulo Gagliardi (Elsevier, 2007)
      Several reports have identified P[6] specificities in humans and in animals in different countries of the world, but few sequence data are available in public databases. In this work we have characterized the VP4 strains ...

    • Molecular epidemiology and temporal evolution of norovirus associated with acute gastroenteritis in Amazonas state, Brazil 

      Hernandez, Juliana Merces; Silva, Luciana Damascena; Sousa Junior, Edivaldo Costa; Bandeira, Renato Silva; Rodrigues, Elmer Abraão Martins; Lucena, Maria Silvia Souza; Costa, Samya Thalita Picanço; Gabbay, Yvone Benchimol (BioMed Central, 2018)
      Background: Globally, Norovirus (NoV) is considered the most common cause of diarrheal episodes across all age groups. Despite its wide genetic diversity, the GII.4 strain is the most predominant and has been associated ...

    • Molecular epidemiology of adenoviruses: global distribution of adenovirus 7 genome types 

      Wadell, Goran; Cooney, Marion K; Linhares, Alexandre da Costa; Silva, Lakshman de; Kennett, Margery L; Kono, Reisaku; Gui-Fang, Ren; Lindman, Kristina; Nascimento, Jussara P; Schoub, Barry D; Smith, Creed D (American Society for Microbiology, 1985)
      Adenovirus 7 (Ad7) is the adenovirus species that most frequently has been associated with severe illness. Seven distinct genome types of adenovirus 7, Ad7p, Ad7a, Ad7b, Ad7c, Ad7d, Ad7e, and Ad7f, can be identified by ...