Nosocomial transmission of an avian-like rotavirus strain among children in Belém, Brazil.
Gusmão, Rosa Helena P
Mascarenhas, Joana D'Arc Pereira
Gabbay, Yvone Benchimol
Linhares, Alexandre da Costa
An atypical group-A rotavirus strain, with an electrophoretype displaying 5 segments in the first dsRNA size class, was detected among 3 hospitalized children less than 2 years old. Detection occurred initially 24 h after admission in a non-diarrhoeic child hospitalized because of acute respiratory infection. The second detection involved a child who occupied a different room within the same ward and who developed nosocomial diarrhoea 48 h later. A third case, also of hospital-acquired diarrhoea, was recorded in a child who occupied a bed in the same room as the second case and developed gastroenteritis 24 h following the second case's detection. In addition to the unusual, avian-like genomic profile, the strain was classified as serotype 2, based on a human VP7-specific enzyme-linked immunosorbent assay (ELISA). The question of whether these events reflect either a genomic rearrangement of a human rotavirus strain or a possible interspecies transmission will be further investigated through hybridization assays.
xmlui.dri2xhtml.METS-1.0.item-citationGUSMÃO, Rosa Helena P. et al. Nosocomial transmission of an avian-like rotavirus strain among children in Belém, Brazil. Journal of Diarrhoeal Diseases Research, v. 12, n. 2, p. 129-132, June 1994.
xmlui.dri2xhtml.METS-1.0.item-decsPrimaryDiarreia Infantil / complicações
Infecções por Rotavirus / isolamento & purificação
Infecções por Rotavirus / virologia
Ensaio de Imunoadsorção Enzimática / métodos