Naturally occurring serotype 2 / subgroup II rotavirus reassortants in Northern Brazil
Mascarenhas, Joana D'Arc Pereira
Linhares, Alexandre da Costa
Gabbay, Yvone Benchimol
Freitas, Ronaldo Barros de
Arias, C. F
Nine serotype 2 human rotavirus strains were isolated in a community-based longitudinal study in Northern Brazil. Five of these strains had a 'long' RNA electrophoretic pattern and all five strains were determined to belong to subgroup II by ELISA assay, in contrast to properties common to serotype 2 human rotaviruses previously characterized. Hybridization studies of one of these unusual strains with 32P-labelled mRNAs derived from the prototype human strains Wa (serotype 1, subgroup II) and S2 (serotype 2, subgroup I) suggested that it was generated by a reassortment event in nature, in which a subgroup II, 'long' electropherotype rotavirus exchanged its serotype-specific gene and gene number 10 for the equivalent genes from a serotype 2, 'short' electropherotype virus.
xmlui.dri2xhtml.METS-1.0.item-citationMASCARENHAS, Joana D’arc Pereira et al. Naturally occurring serotype 2 / subgroup II rotavirus reassortants in Northern Brazil. Virus Research, v. 14, n. 3, p. 235 - 240, Nov. 1989.
xmlui.dri2xhtml.METS-1.0.item-decsPrimaryRNA Viral / genética
Rotavirus / classificação
Rotavirus / genética
Rotavirus / isolamento & purificação