Microssurtos familiares de gastroenterite aguda associada a rotavírus na área de Belém, Pará

Abstract

Estudos foram realizados em 6 famílias residentes na área de Belém-Pará, Brasil, acometidas de diarréia aguda. As taxas de ataque clínico variaram de 25,0% a 71,4%, ocorrendo diarréia, mais freqüentemente, entre as crianças. Diagnóstico de infecção recente por rotavírus foi estabelecido 15 (53,6%) dos 28 pacientes cujos espécimens foram processados laboratorialmente, sendo a faixa etária com maior positividade, 57,1%, a de 1 -5 anos. As técnicas de contra-imuno-eletro-osmoforese e imuno-enzimática ("E LISA"), para a detecção de antígeno de rotavírus, concordaram 61,5%, tendo-se revelado, a primeira, mais sensível.

Episodes of acute diarrhoea associated with rotavirus were studied in 6 families living in Belém, Pará, Brazil. The incidence of gastroenteritis among these families ranged from 25,0% to 71,4%. Diagnosis of rotavirus infection was established in 15 (53,6%) out of the 28 patients whose especimens were processed; it was also shown that children less than 5 years of age were more frequently affected. A comparison was made between the results of counter-imunoelectro-osmophoresis (CI EOF) and enzyme-linked immunosorbent assay (E LISA) tochniques; the two tests agreed in 61,5% but CI EOF yielded slightly more positivies than ELISA.