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dc.contributor.authorMiranda, Silvana Spindola de-
dc.contributor.authorAlmeida, Isabela Neves de-
dc.contributor.authorLopes, Maria Luiza-
dc.contributor.authorFigueiredo, Jamilly dos Reis de-
dc.contributor.authorFigueredo, Lida Jouca de Assis-
dc.contributor.authorKritski, Afrânio Lineu-
dc.contributor.authorCarvalho, Wânia da Silva-
dc.contributor.authorMansur, Maria de Fátima Filardi Oliveira-
dc.date.accessioned2017-11-22T13:46:37Z-
dc.date.available2017-11-22T13:46:37Z-
dc.date.issued2017-
dc.identifier.citationMIRANDA, Silvana Spindola de et al. Evaluation of the commercial kit SIRE Nitratase for detecting resistant Mycobacterium tuberculosis in Brazil. Revista da Sociedade Brasileira de Medicina Tropical, v. 50, n. 4, p. 550-553, July-Aug. 2017.pt_BR
dc.identifier.issn0037-8682-
dc.identifier.urihttp://patua.iec.gov.br//handle/iec/2870-
dc.description.abstractIntroduction: This study aimed to evaluate a new commercial kit, Kit SIRE Nitratase-PlastLabor, for testing the drug susceptibility of clinical Mycobacterium tuberculosis isolates. Methods: The accuracy of the Kit SIRE Nitratase was evaluated by examining the susceptibility (streptomycin, isoniazid, rifampicin, and ethambutol) of 40 M. tuberculosis isolates, using the proportion method with Lowenstein-Jensen medium or the BACTEC MGIT 960 system. Results: The detection accuracy for streptomycin, isoniazid, rifampicin, and ethambutol was 95%, 97.5%, 100%, and 80%, respectively. Conclusions: The exceptional accuracy demonstrated by Kit SIRE Nitratase for isoniazid and rifampicin makes the kit an attractive option for screening M. tuberculosis strain resistance.pt_BR
dc.description.sponsorshipThis study was supported by the Minas Gerais State Research Support Foundation (FAPEMIG) protocol number 65/10 and the National Council for Scientific and Technological Development [Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)] protocol number 310174/2014-7-CNPQ.pt_BR
dc.language.isoengpt_BR
dc.publisherSociedade Brasileira de Medicina Tropicalpt_BR
dc.rightsAcesso Abertopt_BR
dc.titleEvaluation of the commercial kit SIRE Nitratase for detecting resistant Mycobacterium tuberculosis in Brazilpt_BR
dc.typeArtigopt_BR
dc.subject.decsPrimaryMycobacterium tuberculosispt_BR
dc.subject.decsPrimaryMycobacterium tuberculosis / efeitos de drogaspt_BR
dc.subject.decsPrimaryGenes MDR / efeitos de drogaspt_BR
dc.subject.decsPrimaryNitrato Redutasept_BR
dc.subject.decsPrimaryKit SIREpt_BR
dc.creator.affilliationUniversidade Federal de Minas Gerais. Faculdade de Medicina. Grupo de Pesquisa em Micobacterioses. Belo Horizonte, MG, Brasil.pt_BR
dc.creator.affilliationUniversidade Federal de Minas Gerais. Faculdade de Medicina Grupo de Pesquisa em Micobactérias. Belo Horizonte, MG, Brasil.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.creator.affilliationUniversidade Federal de Minas Gerais. Faculdade de Medicina Grupo de Pesquisa em Micobactérias. Belo Horizonte, MG, Brasil.pt_BR
dc.creator.affilliationUniversidade Federal de Minas Gerais. Faculdade de Medicina Grupo de Pesquisa em Micobactérias. Belo Horizonte, MG, Brasil.pt_BR
dc.creator.affilliationUniversidade Federal do Rio de Janeiro. Programa Acadêmico de Tuberculose. Rio de Janeiro, RJ, Brasil.pt_BR
dc.creator.affilliationUniversidade Federal de Minas Gerais. Faculdade de Farmácia. Belo Horizonte, MG, Brasil.pt_BR
dc.creator.affilliationUniversidade Federal de Minas Gerais. Consultoria e Apoio Técnico. Belo Horizonte, MG, Brasil.pt_BR
dc.identifier.doi10.1590/0037-8682-0447-2016-


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