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dc.contributor.authorNunes Neto, Joaquim Pinto-
dc.contributor.authorSouza, William Marciel de-
dc.contributor.authorAcrani, Gustavo Olszanski-
dc.contributor.authorRomeiro, Marilia Farignoli-
dc.contributor.authorFumagalli, Marcílio Jorge-
dc.contributor.authorVieira, Luis Carlos-
dc.contributor.authorMedeiros, Daniele Barbosa de Almeida-
dc.contributor.authorLima, Juliana Abreu-
dc.contributor.authorLima, Clayton Pereira Silva de-
dc.contributor.authorCardoso, Jedson Ferreira-
dc.contributor.authorFigueiredo, Luiz Tadeu Moraes-
dc.contributor.authorSilva, Sandro Patroca da-
dc.contributor.authorTesh, Robert-
dc.contributor.authorNunes, Marcio Roberto Teixeira-
dc.contributor.authorVasconcelos, Pedro Fernando da Costa-
dc.date.accessioned2017-12-04T13:30:46Z-
dc.date.available2017-12-04T13:30:46Z-
dc.date.issued2017-
dc.identifier.citationNUNES NETO, Joaquim Pinto et al. Characterization of the Bujaru, frijoles and Tapara antigenic complexes into the sandfly fever group and two unclassified phleboviruses from Brazil. Journal of General Virology, v. 98, n. 4, p. 585-594, Apr. 2017.pt_BR
dc.identifier.issn0022-1317-
dc.identifier.urihttp://patua.iec.gov.br//handle/iec/2902-
dc.description.abstractThe genus Phlebovirus includes the sandfly fever viruses and tick-transmitted uukuviruses. Sandfly fever group viruses have been isolated from various vertebrate species and from phlebotomines and occasionally alternative arthropods, e.g. mosquitoes, or ceratopogonids of the genus Culicoides. Uukuniemi serogroup viruses have been isolated from various vertebrate species and from ticks. Despite the public health importance of some viruses of the genus, the genomic diversity of phleboviruses that could be incriminated as causative of human or veterinary diseases remains underestimated. Here we describe the nearly complete sequences and genomic characterization of two phleboviruses belonging to the Bujaru antigenic complex: the prototype species and the Munguba virus. Furthermore, six previously unclassified phleboviruses isolated in Brazil were also sequenced and characterized: Ambe, Anhanga, Joa, Uriurana, Urucuri and Tapara viruses. The results of the phylogenetic analysis indicated that these viruses group with viruses of three antigenic complexes (Bujaru, Tapara and frijoles clades), with two unclassified phleboviruses. We also performed genomic reassortment analysis and confirmed that there were no events for the viruses described in this study, but we found a new potential reassortment in Medjerda Valley virus, which contains S and L segments of Arbia virus, and probably a unique M segment, both viruses circulate in the same geographic region, indicating these two isolates represent two distinct viruses. This study provides insights into the genetic diversity, classification and evolution of phleboviruses.pt_BR
dc.description.sponsorshipThis work was supported by the Evandro Chagas Institute funds, Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) grants (301641/2010-2), and by the Fundaçao de Amparo á Pesquisa do Estado de São Paulo, Brazil (grant numbers 13/14929-1 and 14/ 02438-6, and scholarships numbers 12/24150-9, 15/05778-5, 14/ 20851-8, 16/01414-1 and 14/15079-4), Universidade Federal do Pará and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES).pt_BR
dc.language.isoengpt_BR
dc.publisherMicrobiology Societypt_BR
dc.rightsAcesso Abertopt_BR
dc.titleCharacterization of the Bujaru, frijoles and Tapara antigenic complexes into the sandfly fever group and two unclassified phleboviruses from Brazilpt_BR
dc.typeArtigopt_BR
dc.subject.decsPrimaryRoedores / virologiapt_BR
dc.subject.decsPrimaryXenartros / virologiapt_BR
dc.subject.decsPrimaryPsychodidae / virologiapt_BR
dc.subject.decsPrimaryPhlebovirus / classificaçãopt_BR
dc.subject.decsPrimaryPhlebovirus / genéticapt_BR
dc.subject.decsPrimaryPhlebovirus / isolamento & purificaçãopt_BR
dc.subject.decsPrimaryAnálise de Sequência de DNApt_BR
dc.subject.decsPrimaryHomologia de Sequênciapt_BR
dc.subject.decsPrimaryVariação Genéticapt_BR
dc.subject.decsPrimaryGenoma Viralpt_BR
dc.subject.decsPrimaryFilogeniapt_BR
dc.subject.decsPrimaryBrasil (BR)pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.creator.affilliationUniversity of São Paulo. School of Medicine of Ribeirao Preto. ​Virology Research Center. São Paulo, SP, Brazil / MRC-University of Glasgow. Centre for Virus Research. Glasgow, Scotland, UK.pt_BR
dc.creator.affilliationUniversidade Federal da Fronteira Sul. Passo Fundo, RS, Brazil.pt_BR
dc.creator.affilliationUniversity of São Paulo. School of Medicine of Ribeirao Preto. ​Virology Research Center. São Paulo, SP, Brazilpt_BR
dc.creator.affilliationUniversity of São Paulo. School of Medicine of Ribeirao Preto. ​Virology Research Center. São Paulo, SP, Brazilpt_BR
dc.creator.affilliationUniversity of São Paulo. School of Medicine of Ribeirao Preto. ​Virology Research Center. São Paulo, SP, Brazilpt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Centro de Inovação Tecnológica. Belém, PA, Brasil.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Centro de Inovação Tecnológica. Belém, PA, Brasil.pt_BR
dc.creator.affilliationUniversity of São Paulo. School of Medicine of Ribeirao Preto. ​Virology Research Center. São Paulo, SP, Brazilpt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Centro de Inovação Tecnológica. Belém, PA, Brasil.pt_BR
dc.creator.affilliationUniversity of Texas Medical Branch. Department of Pathology. Galveston TX, USA.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Belém, PA, Brazil / Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Centro de Inovação Tecnológica. Belém, PA, Brazil / University of Texas Medical Branch. Department of Pathology. Galveston TX, USA.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Belém, PA, Brazil / Pará State University. Department of Pathology. Belém, PA, Brazil.pt_BR
dc.identifier.doi10.1099/jgv.0.000724-


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