SAARB - Artigos Científicos
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Os documentos disponíveis no repositório são de propriedade e responsabilidade de seus autores, conforme a legislação que rege o direito autoral no país (Lei nº 9.610 , de 19.02.98).
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Serum soluble mediator profiles and networks during acute infection with distinct DENV serotypes
(Frontiers Media, 2022)A panoramic analysis of chemokines, pro-inflammatory/regulatory cytokines, and growth factors was performed in serum samples from patients with acute DENV infection (n=317) by a high-throughput microbeads array. Most soluble ... -
Discovery and genome sequencing of a new virus related to members of the family Tymoviridae, isolated from mosquitoes of the genus Mansonia in Brazil
(Springer, 2022)A new virus, named Mutum virus, related to members of the family Tymoviridae, was isolated from mosquitoes (Mansonia spp.) in clone C6/36 cells, and its complete genome was sequenced. Its genome is 6494 nt in size with an ... -
Description of mitochon genome and phylogenetic considerations of Sabethes bipartipes, Sabethes cyaneus, Sabethes quasicyaneus, and Sabethes tarsopus (Diptera: Culicidae)
(Elsevier, 2022)The genus Sabethes (Diptera: Culicidae) comprises species of great epidemiological relevance, particularly involved in transmission cycles of the Yellow fever virus in South America. Given the unavailability of information ... -
Description of the mitogenome and phylogeny of Aedes spp. (Diptera: Culicidae) from the Amazon region
(Elsevier, 2022)The genus Aedes (Diptera: Culicidae) includes species of great epidemiological relevance, particularly involved in transmission cycles of leading arboviruses in the Brazilian Amazon region, such as the Zika virus (ZIKV), ... -
Absence of anti-RBD antibodies in SARS-CoV-2 infected or naive individuals prior to vaccination with CoronaVac leads to short protection of only four months duration
(MDPI, 2022)Abstract: The COVID-19 pandemic is the biggest public health threat facing the world today. Multiple vaccines have been approved; however, the emergence of viral variants such as the recent Omicron raises the possibility ... -
Single cell multiomic approaches to disentangle T cell heterogeneity
(Elsevier, 2022)Single-cell multi-omics is a rapidly evolving field, thanks to a fast technological improvement and the growing accuracy of dedicated computational tools for data analysis. Its importance is highlighted by the possibility ... -
Unequal burden of Zika-associated microcephaly among populations with public and private healthcare in Salvador, Brazil
(Elsevier, 2022)Objectives: To describe the differences in clinical presentation and relative disease burden of congenital Zika syndrome (CZS)-associated microcephaly at 2 large hospitals in Salvador, Brazil that serve patients of different ... -
Was It Chikungunya? Laboratorial and clinical investigations of cases occurred during a Triple Arboviruses’ Outbreak in Rio de Janeiro, Brazil
(MDPI, 2022)The co-circulation of chikungunya virus (CHIKV), dengue virus (DENV) and Zika virus (ZIKV) in Rio de Janeiro (RJ), Brazil, caused a challenging triple epidemic, as they share similar clinical signs and symptoms and ... -
Phylogeny of Anopheles darlingi (Diptera:Culicidae) based on the antimicrobial peptide genes cecropin and defensin
(Elsevier, 2022)Cecropins and defensins are the main classes of antimicrobial peptides in the mosquito innate immune system, acting against bacteria, fungi and protozoa. There is a knowledge gap concerning these peptide genes in anopheline ... -
Biological characterization of yellow fever viruses isolated from non-human primates in Brazil with distinct genomic landscapes
(Frontiers Media, 2022)Since the beginning of the XXI Century, the yellow fever virus (YFV) has been cyclically spreading from the Amazon basin to Brazil’s South and Southeast regions, culminating in an unprecedented outbreak that started in ... -
Arbovirus outbreak in a rural region of the Brazilian Amazon
(Elsevier, 2022)Background: An outbreak of febrile illness was reported from January to February 2018 in the Expedito Ribeiro Settlement, Santa Bárbara do Pará municipality, Pará State, Brazil. Objective: This study aimed to investigate ... -
The first evidence of hepatitis A virus subgenotype IIIA in the Eastern Brazilian Amazon, 1982-1983
(Wiley, 2022)Hepatitis A virus (HAV) is a major causative agent of acute hepatitis worldwide. Although discovered in 1973, due to limitations of applicable serological and/or molecular methods, HAV remained under limited diagnosis until ... -
Negeviruses isolated from mosquitoes in the Brazilian Amazon
(BMC, 2022)Background: There are several groups of viruses including Insect Specific Viruses (ISV) such as the taxon Negevirus, a group of viruses phylogenetically related to plant viruses. Negeviruses replicate in mosquito cells, ... -
Endothelium activation during severe yellow fever triggers an intense cytokine-mediated inflammatory response in the liver parenchyma
(MDPI, 2022)Yellow fever (YF) is a pansystemic disease caused by the yellow fever virus (YFV), the prototype species of the family Flaviviridae and genus Flavivirus, and has a highly complex host-pathogen relationship, in which ... -
Whole-genome sequencing of Leishmania infantum chagasi isolates from Honduras and Brazil
(American Society for Microbiology, 2021)This work reports on the whole-genome sequencing of Leishmania infantum chagasi from Honduras (Central America) and Brazil (South America). -
Unwanted exacerbation of the immune response in neurodegenerative disease: a time to review the impact
(Frontiers Media, 2021)The COVID-19 pandemic imposed a series of behavioral changes that resulted in increased social isolation and a more sedentary life for many across all age groups, but, above all, for the elderly population who are the most ... -
First description of the mitogenome and phylogeny of culicinae species from the Amazon Region
(MDPI, 2021)The Culicidae family is distributed worldwide and comprises about 3587 species subdivided into the subfamilies Anophelinae and Culicinae. This is the first description of complete mitochondrial DNA sequences from Aedes ... -
Occurrence of tick-borne diseases in domestic dogs in Belém, Pará, Brazil
(Universidade Federal Rural do Semi-Árido, 2021)Tick-borne blood cell pathogens, which are challenging to diagnose, are primarily detected using molecular techniques. Therefore, this study aimed to detect the main infectious agents involved in 50 cases of suspected ... -
Whole-genome sequencing of alcaligenes faecalis HZ01, with potential to inhibit nontuberculous mycobacterial growth
(American Society for Microbiology, 2021)Alcaligenes faecalis is a Gram-negative rod that is ubiquitous in the environment and is an opportunistic human pathogen. Here, we report the whole-genome sequencing analysis of A. faecalis HZ01, which presents mycobacterial ... -
Molecular diagnosis and clinicopathological characteristics of canine distemper neurologic disease
(FUNPEC-EDITORA, 2021)Canine distemper is a highly infectious disease, distributed throughout the world. It is characterized by lymphotropism, neurotropism, and epitheliotropism, resulting in severe clinical changes and death. We report on the ...