Prevalence of human herpesvirus 8 antibodies in the population of Belém, Pará, Brasil
Freitas, Ronaldo Barros de
Freitas, Maria Rute
Linhares, Alexandre da Costa
Serum samples from 497 children and adults inhabiting two neighbourhoods (Guamá and Terra Firme) in Belém, Pará, North Brazil were screened for the presence of human herpesvirus 8 (HHV-8) antibody using an enzyme-linked immunosorbent assay. An overall 16.3 percent prevalence was found for these urban communities. Taken both genders together, prevalence rates of HHV-8 antibody increase gradually, across age-groups, ranging from 12.0 percent to 33.3 percent. When seroprevalence is analysed by gender, similar rates are found for female (18.4 percent) and male (14.0 percent) individuals. In the former gender group, seroprevalence rates increased from 10.3 percent, in children ú 10 years of age, to 30.0 percent in adults 41-50 years of age. Conversely, among male subjects, the prevalence of HHV-8 antibodies decreased from 13.3 percent in children/young adults aged ú 10 to 20 years of age to 6.1 percent in adults aged 21-30 years. From the 31-40 year-old group male onwards, seropositivity rates increased gradually, ranging from 8.3 percent to 66.7 percent. A significant difference in seropositivity rates was noted when comparing 21-30 age groups for female and male subjects: 23.3 percent and 6.1 percent, respectively (P = 0.03). Geometric mean optical densities were found to increase slightly from the lower to the higher age-groups. Our data suggest that transmission of HHV-8 occurs frequently in the general urban population of Belém, and that prevalence of antibody seems to increase with age.
xmlui.dri2xhtml.METS-1.0.item-citationFREITAS, Ronaldo Barros de; FREITAS, Maria Rute; LINHARES, Alexandre da Costa. Prevalence of human herpesvirus 8 antibodies in the population of Belém, Pará, Brasil. Revista do Instituto de Medicina Tropical de São Paulo, v. 44, n. 6, p. 309-313, Nov.-Dec. 2002.
xmlui.dri2xhtml.METS-1.0.item-decsPrimaryHerpesvirus Humano 8 / classificação
Herpesvirus Humano 8 / isolamento & purificação