Human disease in Ribeira Valley, Brazil caused by Caraparu, a Group C arbovirus: report of a case

Abstract

Relatam-se os dados clinicos e laboratoriais de um caso de molestia humana causada por virus identico ou antigenicamente muito relacionado ao arbovirus do Grupo C Caraparu, em um morador da regiao do Vale do Ribeira, Estado de Sao Paulo, sudeste do Brasil. O fato apresenta interesse medico sanitario pois embora existam evidencias da presenca de inumeros arbovirus na area, os unicos casos comprovados de doenca por esses agentes foram os de encefalite pelo virus Rocio durante a epidemia ocorrida em 1975-1977. Os resultados dos testes sorologicos sugerem diferenca anti-genica entre as cepas de virus Caraparu isoladas nos Estados de Sao Paulo e Para e proximidade antigenica entre a cepa de Caraparu de Sao Paulo e o virus Bruconha.

The cllnical and laboratory data of a disease in a resident of Ribeira Valley,São Paulo State, southeastern Brazil, caused by an agent close or identical toGaraparu, a Group C arbovirus, was described. Although there is evidence of an intensive circulation of several arboviruses in the area, no diagnosis of human disease by these egents has been made, except the encephalitis cases caused by Rocio virus during an epidemic in 1975-1977. An antigenic difference between Caraparu strains isolated in São Paulo and in Pará States and a close antigenic relationship between Caraparu strain from São Paulo and Bruconha virus were suggested by the serological tests.