Human T Lymphotropic virus and pulmonary diseases
Dias, Apio R. N
Falcão, Luiz F. M
Falcão, Aline S. C
Normando, Valéria M. F
Quaresma, Juarez Antônio Simões
Human T lymphotropic virus type 1 (HTLV-1) is the etiological agent of HTLV1-associated myelopathy, and adult T cell lymphoma/leukemia (ATL/L). Pulmonary complications such as alveolitis and bronchiectasis were found in individuals who develop TSP/HAM due to chronic inflammation. These individuals showed image anomalies in CT scans and changes in pulmonary function parameters distinctive of pulmonary disease. Furthermore, infected individuals have a greater susceptibility to pulmonary tuberculosis either due to changes in the innate immune response, in asymptomatic carriers, or to an opportunistic disease linked to immunodepression, in individuals who develop ATL/L. This summary addresses the general lack of knowledge regarding the relationship between HTLV-1 and pulmonary diseases and provides direction for future work.
xmlui.dri2xhtml.METS-1.0.item-citationDIAS, Apio R. N. et al. Human T Lymphotropic virus and pulmonary diseases. Frontiers in Microbiology, v. 9, p. 1-7, art. 1879, Aug. 2018.
xmlui.dri2xhtml.METS-1.0.item-decsPrimaryVírus 1 Linfotrópico T Humano / patogenicidade
Infecções por HTLV-I
Pulmão / anatomia & histologia