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A novel hepacivirus in wild rodents from South America

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2019
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A novel hepacivirus in wild rodents from South America.pdf (1.411xmlui.dri2xhtml.METS-1.0.size-megabytes)
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http://patua.iec.gov.br//handle/iec/3633
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Souza, William Marciel de
Fumagalli, Marcílio Jorge
Santos Jr, Gilberto Sabino
Maia, Felipe Gonçalves Motta
Modha, Sejal
Nunes, Márcio Roberto Teixeira
Murcia, Pablo Ramiro
Figueiredo, Luiz Tadeu Moraes
xmlui.dri2xhtml.METS-1.0.item-abstract
The Hepacivirus genus comprises single-stranded positive-sense RNA viruses within the family Flaviviridae. Several hepaciviruses have been identified in different mammals, including multiple rodent species in Africa, Asia, Europe, and North America. To date, no rodent hepacivirus has been identified in the South American continent. Here, we describe an unknown hepacivirus discovered during a metagenomic screen in Akodon montensis, Calomys tener, Oligoryzomys nigripes, Necromys lasiurus, and Mus musculus from São Paulo State, Brazil. Molecular detection of this novel hepacivirus by RT-PCR showed a frequency of 11.11% (2/18) in Oligoryzomys nigripes. This is the first identification of hepavivirus in sigmondonine rodents and in rodents from South America. In sum, our results expand the host range, viral diversity, and geographical distribution of the Hepacivirus genus.
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SOUZA, William Marciel de et al. A novel hepacivirus in wild rodents from South America. Viruses. v. 11, n. 3, e297, p. 1-7, Mar. 2019.
xmlui.dri2xhtml.METS-1.0.item-decsPrimary
Hepacivirus / isolamento & purificação
Hepatite C / patologia
Flaviviridae / patogenicidade
Arvicolinae / virologia
Camundongos
Doenças dos Roedores / virologia
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Instituto Evandro Chagas - SVS - MS - 2007-2018 Rodovia BR316 km 7 sn - Levilandia - 67030-000 - Ananindeua - Para - Brasil.
Licença Creative CommonsEste trabalho está licenciado com uma Licença Creative Commons - Atribuição-NãoComercial 4.0 Internacional
Tel: (55 91) 3214-2191
Email: biblioteca@iec.gov.br / clariceneta@iec.gov.br
 

 

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Instituto Evandro Chagas - SVS - MS - 2007-2018 Rodovia BR316 km 7 sn - Levilandia - 67030-000 - Ananindeua - Para - Brasil.
Licença Creative CommonsEste trabalho está licenciado com uma Licença Creative Commons - Atribuição-NãoComercial 4.0 Internacional
Tel: (55 91) 3214-2191
Email: biblioteca@iec.gov.br / clariceneta@iec.gov.br