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Detection and molecular epidemiology of human bocavirus in children with acute gastroenteritis from Brazil

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2018
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Detection and molecular epidemiology of human bocavirus in children with acute gastroenteritis from Brazil.pdf (295.7xmlui.dri2xhtml.METS-1.0.size-kilobytes)
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http://patua.iec.gov.br//handle/iec/3639
xmlui.dri2xhtml.METS-1.0.item-author
Soares, Luana da Silva
Lima, A. B
Pantoja, K. C
Lobo, Patrícia dos Santos
Cruz, J. F
Guerra, Sylvia de Fátima dos Santos
Bezerra, D. A. M
Bandeira, R. S
Mascarenhas, Joana D'Arc Pereira
xmlui.dri2xhtml.METS-1.0.item-abstract
Human Bocavirus (HBoV) is a recently discovered virus and was first detected in the nasopharyngeal aspirate samples and after in stool samples, suggesting that HBoV may be a causative agent for human enteric infections. Due to absence of treatment options, there is a need to understand the disease-causing mechanism of these viruses. The aim of this was to demonstrate the prevalence of HBoV from children less than 10 years with acute gastroenteritis in Brazil, during November 2011 to November 2012. Stool samples from hospitalized children ≤ 10 years who presented symptoms of acute gastroenteritis were analyzed for the presence of HBoV DNA by nested-PCR. HBoVpositivity was detected in 24.0% (54/225) of samples. Two peaks of HBoV detection were observed, during November 2011 and July to September 2012. Co-infections between HBoV and rotavirus A were identified in 50.0% (27/54) of specimens. Phylogenetic analysis identified the presence of HBoV-1 (94.8%), HBoV-2 (2.6%) and HBoV-3 (2.6%) species, with only minor variations among them. Further investigations are necessary to improve the knowledge on the role of HBoV in gastrointestinal infections.
xmlui.dri2xhtml.METS-1.0.item-citation
SOARES, Luana da Silva et al. Detection and molecular epidemiology of human bocavirus in children with acute gastroenteritis from Brazil. bioRxiv, e404632, p. 1-17, 2018.
xmlui.dri2xhtml.METS-1.0.item-decsPrimary
Bocavirus Humano / patogenicidade
Infecções por Parvoviridae / virologia
Gastroenterite / virologia
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Acesso Aberto
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  • SAVIR - Artigos Científicos

Instituto Evandro Chagas - SVS - MS - 2007-2018 Rodovia BR316 km 7 sn - Levilandia - 67030-000 - Ananindeua - Para - Brasil.
Licença Creative CommonsEste trabalho está licenciado com uma Licença Creative Commons - Atribuição-NãoComercial 4.0 Internacional
Tel: (55 91) 3214-2191
Email: biblioteca@iec.gov.br / clariceneta@iec.gov.br
 

 

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Instituto Evandro Chagas - SVS - MS - 2007-2018 Rodovia BR316 km 7 sn - Levilandia - 67030-000 - Ananindeua - Para - Brasil.
Licença Creative CommonsEste trabalho está licenciado com uma Licença Creative Commons - Atribuição-NãoComercial 4.0 Internacional
Tel: (55 91) 3214-2191
Email: biblioteca@iec.gov.br / clariceneta@iec.gov.br