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dc.contributor.authorSoares, Luana da Silva-
dc.contributor.authorLima, A. B-
dc.contributor.authorPantoja, K. C-
dc.contributor.authorLobo, Patrícia dos Santos-
dc.contributor.authorCruz, J. F-
dc.contributor.authorGuerra, Sylvia de Fátima dos Santos-
dc.contributor.authorBezerra, D. A. M-
dc.contributor.authorBandeira, R. S-
dc.contributor.authorMascarenhas, Joana D'Arc Pereira-
dc.date.accessioned2019-04-12T12:23:09Z-
dc.date.available2019-04-12T12:23:09Z-
dc.date.issued2018-
dc.identifier.citationSOARES, Luana da Silva et al. Detection and molecular epidemiology of human bocavirus in children with acute gastroenteritis from Brazil. bioRxiv, e404632, p. 1-17, 2018.pt_BR
dc.identifier.urihttp://patua.iec.gov.br//handle/iec/3639-
dc.description.abstractHuman Bocavirus (HBoV) is a recently discovered virus and was first detected in the nasopharyngeal aspirate samples and after in stool samples, suggesting that HBoV may be a causative agent for human enteric infections. Due to absence of treatment options, there is a need to understand the disease-causing mechanism of these viruses. The aim of this was to demonstrate the prevalence of HBoV from children less than 10 years with acute gastroenteritis in Brazil, during November 2011 to November 2012. Stool samples from hospitalized children ≤ 10 years who presented symptoms of acute gastroenteritis were analyzed for the presence of HBoV DNA by nested-PCR. HBoVpositivity was detected in 24.0% (54/225) of samples. Two peaks of HBoV detection were observed, during November 2011 and July to September 2012. Co-infections between HBoV and rotavirus A were identified in 50.0% (27/54) of specimens. Phylogenetic analysis identified the presence of HBoV-1 (94.8%), HBoV-2 (2.6%) and HBoV-3 (2.6%) species, with only minor variations among them. Further investigations are necessary to improve the knowledge on the role of HBoV in gastrointestinal infections.pt_BR
dc.language.isoengpt_BR
dc.publisherCold Spring Harbor Laboratorypt_BR
dc.rightsAcesso Abertopt_BR
dc.titleDetection and molecular epidemiology of human bocavirus in children with acute gastroenteritis from Brazilpt_BR
dc.typeArtigopt_BR
dc.subject.decsPrimaryBocavirus Humano / patogenicidadept_BR
dc.subject.decsPrimaryInfecções por Parvoviridae / virologiapt_BR
dc.subject.decsPrimaryGastroenterite / virologiapt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.identifier.doi10.1101/404632-


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