• Emergence of new insect-restrictive viruses in the Amazon Region 

      Nunes, Márcio Roberto Teixeira; Silva, Sandro Patroca da; Carvalho, Valéria Lima; Vasconcelos, Janaina Mota de; Silva, Daisy Elaine Andrade da; Oliveira, Layanna Freitas de; Nunes Neto, Joaquim Pinto; Rodrigues, Sueli Guerreiro; Azevedo, Raimunda do Socorro da Silva; Monteiro, Hamilton A. O; Cardoso, Jedson Ferreira; Guzman, Hilda; Tesh, Robert; Vasconcelos, Pedro Fernando da Costa; Vianez Júnior, João Lídio da Silva Gonçalves; Martins, Lívia Caricio (American Society for Microbiology, 2015)
      The complete genome was determined for 12 viruses isolated from 8 different pools of mosquitoes (Culex sp. and Psorophora ferox) collected at Brejeira farm, Canaan dos Carajas, Para state in northern Brazil. Eight of the ...
    • Establishment of a minigenome system for Oropouche virus reveals the S genome segment to be significantly longer than reported previously 

      Acrani, Gustavo Olszanski; Tilston-Lunel, Natasha L; Spiegel, Martin; Weidmann, Manfred; Dilcher, Meik; Silva, Daisy Elaine Andrade da; Nunes, Márcio Roberto Teixeira; Elliott, Richard M (Microbiology Society, 2015)
      Oropouche virus (OROV) is a medically important orthobunyavirus, which causes frequent outbreaks of a febrile illness in the northern parts of Brazil. However, despite being the cause of an estimated half a million human ...
    • Evaluation of drug susceptibility profile of mycobacterium tuberculosis lineage 1 from brazil based on whole genome sequencing and phenotypic methods 

      Guimarães, Arthur Emil dos Santos; Sharma, Abhinav; Furlaneto, Ismari Perini; Rutaihwa, Liliana; Cardoso, Jedson Ferreira; Conceição, Marília Lima da; Spinassé, Lizânia Borges; Machado, Edson; Lopes, Maria Luiza; Duarte, Rafael Silva; Gagneux, Sebastien; Suffys, Philip Noel; Lima, Karla Valéria Batista; Conceição, Emilyn Costa (Instituto Oswaldo Cruz, 2020)
      BACKGROUND The evaluation of procedures for drug susceptibility prediction of Mycobacterium tuberculosis based on genomic data against the conventional reference method test based on culture is realistic considering the ...
    • Evolutionary and molecular analysis of complete genome sequences of norovirus from Brazil: emerging recombinant strain GII.P16/GII.4 

      Hernandez, Juliana Merces; Silva, Luciana Damascena da; Sousa Júnior, Edivaldo Costa; Cardoso, Jedson Ferreira; Reymão, Tammy Kathlyn Amaral; Portela, Ana Caroline Rodrigues; Lima, Clayton Pereira Silva de; Teixeira, Dielle Monteiro; Lucena, Maria Silvia Souza; Nunes, Márcio Roberto Teixeira; Gabbay, Yvone Benchimol (Frontiers Media, 2020)
      Noroviruses (NoVs) are enteric viruses that cause acute gastroenteritis, and the pandemic GII.4 genotype is spreading and evolving rapidly. The recombinant GII.P16/GII.4_Sydney strain emerged in 2016, replacing ...
    • Evolutionary dynamics of Oropouche virus in South America 

      Gutierrez, Bernardo; Wise, Emma L; Pullan, Steven T; Logue, Christopher H; Bowden, Thomas A; Escalera-Zamudio, Marina; Trueba, Gabriel; Nunes, Márcio Roberto Teixeira; Faria, Nuno Rodrigues; Pybus, Oliver G (American Society for Microbiology, 2020)
      The Amazon basin is home to numerous arthropod-borne viral pathogens that cause febrile disease in humans. Among these, Oropouche orthobunyavirus (OROV) is a relatively understudied member of the genus Orthobunyavirus, ...
    • Fatal outcome of chikungunya virus infection in Brazil 

      Lima, Shirlene Telmos Silva de; Souza, William Marciel de; Cavalcante, John Washington; Candido, Darlan da Silva; Fumagalli, Marcilio Jorge; Carrera, Jean-Paul; Mello, Leda Maria Simões; Araújo, Fernanda Montenegro de Carvalho; Ramalho, Izabel Leticia Cavalcante; Barreto, Francisca Kalline de Almeida; Braga, Deborah Nunes de Melo; Simião, Adriana Rocha; Silva, Mayara Jane Miranda da; Oliveira, Rhaquel de Morais Alves Barbosa; Lima, Clayton Pereira Silva de; Lins, Camila de Sousa; Barata, Rafael Ribeiro; Melo, Marcelo Nunes Pereira; Souza, Michel Platini Caldas de; Franco, Luciano Monteiro; Távora, Fábio Rocha Fernandes; Lemos, Daniele Rocha Queiroz; Alencar, Carlos Henrique Morais de; Jesus, Ronaldo de; Fonseca, Vagner de Souza; Dutra, Leonardo Hermes; Abreu, André Luiz de; Araújo, Emerson Luiz Lima; Freitas, André Ricardo Ribas; Vianez Júnior, João Lídio da Silva Gonçalves; Pybus, Oliver G; Figueiredo, Luiz Tadeu Moraes; Faria, Nuno Rodrigues; Nunes, Márcio Roberto Teixeira; Cavalcanti, Luciano Pamplona de Góes; Miyajima, Fabio (Oxford University Press, 2021)
      BACKGROUND: Chikungunya virus (CHIKV) emerged in the Americas in 2013 and has caused approximately 2.1 million cases and >600 deaths. A retrospective investigation was undertaken to describe clinical, epidemiological, and ...
    • Field and classroom initiatives for portable sequence-based monitoring of dengue virus in Brazil 

      Adelino, Talita Émile Ribeiro; Giovanetti, Marta; Fonseca, Vagner; Xavier, Joilson; Abreu, Álvaro Salgado de; Nascimento, Valdinete Alves do; Demarchi, Luiz Henrique Ferraz; Oliveira, Marluce Aparecida Assunção; Silva, Vinícius Lemos da; Mello, Arabela Leal e Silva de; Cunha, Gabriel Muricy; Santos, Roselene Hans; Oliveira, Elaine Cristina de; Chamon Júnior, Jorge Antônio; Iani, Felipe Campos de Melo; Filippis, Ana Maria Bispo de; Abreu, André Luiz de; Jesus, Ronaldo de; Albuquerque, Carlos Frederico Campelo de; Rico, Jairo Mendez; Said, Rodrigo Fabiano do Carmo; Silva, Joscélio Aguiar; Moura, Noely Fabiana Oliveira de; Leite, Priscila; Frutuoso, Lívia Carla Vinhal; Haddad, Simone Kashima; Martínez, Alexander; Barreto, Fernanda Khouri; Vazquez, Cynthia Carolina; Cunha, Rivaldo Venâncio da; Araújo, Emerson Luiz Lima; Tosta, Stephane Fraga de Oliveira; Fabri, Allison de Araújo; Chalhoub, Flávia Lowen Levy; Lemos, Poliana da Silva; Nogueira, Fernanda de Bruycker; Lichs, Gislene Garcia de Castro; Zardin, Marina Castilho Souza Umaki; Segovia, Fátima María Cardozo; Gonçalves, Crhistinne Cavalheiro Maymone; Grillo, Zoraida Del Carmen Fernandez; Slavov, Svetoslav Nanev; Pereira, Luiz Augusto; Mendonça, Ana Flávia; Pereira, Felicidade Mota; Magalhães, Jurandy Júnior Ferraz de; Santos Júnior, Agenor de Castro Moreira dos; Lima, Maricélia Maia de; Nogueira, Rita Maria Ribeiro; Góes Neto, Aristóteles; Azevedo, Vasco Ariston de Carvalho; Ramalho, Dario Brock; Oliveira, Wanderson Kleber; Macario, Eduardo Marques; Medeiros, Arnaldo Correia de; Pimentel, Victor; Holmes, Edward C; Oliveira, Tulio de; Lourenço, José; Alcantara, Luiz Carlos Júnior; Cerqueira, Erenilde Marques de; Graf, Tiago; Ramalho, Walter; Navegantes, Wildo; Reis, Renato Barbosa; Duarte, Clara Guerra; Pereira, Maria Alves; Silva, Paulo Eduardo de Souza da; Souza, Raoni Almeida de; Pauvolid-Corrêa, Alex; Paiva, Anne Aline Pereira de; Fritsch, Hegger Machado; Mares-Guia, Maria Angélica; Torres, Maria Celeste; Lima, Maurício Teixeira; Sequeira, Patrícia; Marques, William de Almeida; Jesus, Jorlan Fernandes de; Naveca, Felipe Gomes; Silva, Alessandra Lima; Pinto, Anne Cybelle; Jaiswal, Arun Kumar; Lopes, Élisson Nogueira; Costa, Francielly Morais Rodrigues da; Peixoto, Gabriel Quintanilha; Soares, Gilson Carlos; Fonseca, Paula Luize Camargos; Souza, Renan Pedra de; Kato, Rodrigo Bentes; Santos, Rodrigo Profeta Silveira; Tiwari, Sandeep; Nogueira, Wylerson Guimarães; Santos, Beatriz Senra Álvares da Silva; Bueno, Bruna Lopes; Siqueira, Isadora Cristina de; Valle, Lourdes Farre; Borba, Melina Mosquera Navarro; Mazzetto, Alix Sandra; Aguiar, Francisco de Assis Araújo; Gomes, Irenio da Silva; Abrantes, Jayra Juliana Paiva Alves; Watanabe, Luiz Takao; Rego, Marta Ferreira da Silva; Nardy, Vanessa Brandão; Aguiar, Shirlei Ferreira de; Santos, Fabiana Cristina Pereira dos; Queiroz, Alice Louize Nunes; Nunes, Bruno Tardelli Diniz; Martins, Lívia Caricio; Nunes, Márcio Roberto Teixeira; Salles, Flávia Cristina da Silva; Claro, Ingra Morales; Jesus, Jaqueline Goes de; Cândido, Darlan da Silva; Fabbri, Cintia Marcela; González, Claudia; Saéz, Lisseth; Chen-Germán, María; Barrera, Jaime Lagos; Ramírez-González, José Ernesto; Campos, Josefina; Faller, Noelia Morel; Villalobos, Marta Eugenia Víquez; Kaslin, Roberto; Cisneros, Silvia Paola Salgado; Aburjaile, Flávia Figueira; Amaral, Carolina Dourado; Freire, Danielle Bandeira Costa de Sousa; Cruz, Laura Nogueira; Mattos, Daniel; Landeira, Leandro Ferreira Lopes; Menezes, Mariane Talon de; Orioli, Ieda Maria; Ferraz, Ariane Coelho; Oliveira, Daiane Teixeira de; Reis, Alexandre Barbosa; Cota, Renata Guerra de Sá; Bezerra, Rafael dos Santos; Falcão, Melissa Barreto; Carvalho, Rodrigo Dias de Oliveira (Nature Research, 2021)
      Brazil experienced a large dengue virus (DENV) epidemic in 2019, highlighting a continuous struggle with effective control and public health preparedness. Using Oxford Nanopore sequencing, we led field and classroom ...
    • First isolation of Bunyamwera virus (Bunyaviridae family) from horses with neurological disease and an abortion in Argentina 

      Tauro, Laura B; Rivarola, Maria E; Lucca, Eduardo; Mariño, Betina; Mazzini, Rubén; Cardoso, Jedson Ferreira; Barrandeguy, María Edith; Nunes, Márcio Roberto Teixeira; Contigiani, Marta S (Elsevier, 2015)
      Bunyamwera virus (BUNV) is the prototype virus for both the Orthobunyavirus genus and the Bunyaviridae family. Different strains of BUNV have been associated with clinical diseases in domestic animals, mainly ruminants. ...
    • First new world primate papillomavirus identification in the Atlantic Forest, Brazil: Alouatta guariba papillomavirus 1 

      Silvestre, Rodrigo Vellasco Duarte; Souza, Alex Junior Souza de; Sousa Júnior, Edivaldo Costa; Silva, Allan Kaio; Mello, Wyller Alencar de; Nunes, Márcio Roberto Teixeira; Vianez Júnior, João Lídio da Silva Gonçalves; Cardoso, Jedson Ferreira; Vasconcelos, Janaina Mota de; Oliveira, Layanna Freitas de; Silva, Sandro Patroca da; Silva, Adriana Marques J. da; Fries, Brigida Gomes; Summa, Maria Eugênia L; Sá, Lilian Rose Marques de (American Society for Microbiology, 2016)
      We report here the complete genome sequence of the first papillomavirus detected in a New World primate, howler monkey, Alouatta guariba clamitans papillomavirus 1 (AgPV1), from the Atlantic Forest in São Paulo State, Brazil.
    • Full-length genomic and molecular characterization of Canine parvovirus in dogs from North of Brazil. 

      Silva, S. P.; Silva, L. N. P. P.; Rodrigues, E. D. L.; Cardoso, J. F.; Tavares Neto, Fernando; Souza, W. M.; Santos, C. M. P.; Martins, F. M. S.; Jesus, I. S.; Brito, T. C.; Moura, T. P. C.; Nunes, Márcio Roberto Teixeira; Casseb, Lívia Medeiros Neves; Silva Filho, E.; Casseb, A. R. (2017)
      With the objective of characterizing Canine parvovirus (CPV) from some suspected fecal samples of dogs collected from the Veterinarian Hospital in Belém city, five positive samples were found by PCR assay and an update ...
    • Genetic characterization of the Patois Serogroup (Genus Orthobunyavirus; Family Peribunyaviridae) and evidence that Estero Real Virus is a member of the Genus Orthonairovirus 

      Aguilar, Patricia V; Souza, William Marciel de; Silvas, Jesus A; Wood, Thomas; Widen, Steven; Fumagalli, Marcílio Jorge; Nunes, Márcio Roberto Teixeira (American Society of Tropical Medicine and Hygiene, 2018)
      Estero Real virus (ERV) was isolated in 1980 from Ornithodoros tadaridae ticks collected in El Estero Real, Sancti Spiritus, Cuba. Antigenic characterization of the isolate based on serological methods found a relationship ...
    • Genetic diversity of Hepatozoon spp. in Hydrochoerus hydrochaeris and Pecari tajacu from eastern Amazon 

      Gomes, Laise de Azevedo; Moraes, Leopoldo Augusto; Aguiar, Délia Cristina Figueira; Dias, Hilma Lúcia Tavares; Ribeiro, Ana Silvia Sardinha; Rocha, Henrique Piram do Couto; Nunes, Márcio Roberto Teixeira; Gonçalves, Evonnildo Costa (Elsevier, 2018)
      This study aimed to identify and characterize genetically species of the genus Hepatozoon detected in Hydrochoerus hydrochaeris (capybaras) and Pecari tajacu (collared peccaries) from two localities from the Eastern Amazon. ...
    • Genome sequence of chiqui virus, a novel reovirus isolated from mosquitoes collected in Colombia 

      Contreras-Gutiérrez, María Angélica; Guzman, Hilda; Cardoso, Jedson Ferreira; Popov, Vsevolod Leonidovich; Nunes, Márcio Roberto Teixeira; Uribe, Sandra; Widen, Steven G; Wood, Thomas G; Vasilakis, Nikos; Tesh, Robert B (American Society for Microbiology, 2018)
      We report here the complete genome sequence of a novel reovirus, designated Chiqui virus (CHQV) strain CoB38d, that was isolated from a pool of unidentified mosquitoes collected in northern Colombia in 2013. CHQV has ...
    • Genomic and epidemiological surveillance of Zika virus in the Amazon region 

      Giovanetti, Marta; Faria, Nuno Rodrigues; Lourenço, José; Jesus, Jaqueline Goes de; Xavier, Joilson; Claro, Ingra Morales; Kraemer, Moritz U. G; Fonseca, Vagner; Dellicour, Simon; Théze, Julien; Salles, Flavia da Silva; Graf, Tiago; Silveira, Paola Paz; Nascimento, Valdinete Alves do; Souza, Victor Costa de; Iani, Felipe Campos de Melo; Martins, Emerson Augusto Castilho; Cruz, Laura Nogueira; Wallau, Gabriel; Fabri, Allison; Levy, Flávia; Quick, Joshua; Azevedo, Vasco de; Aguiar, Renato Santana de; Oliveira, Tulio de; Menezes, Camila Bôtto de; Castilho, Marcia da Costa; Terra, Tirza Matos; Silva, Marineide Souza da; Filippis, Ana Maria Bispo de; Abreu, André Luiz de; Oliveira, Wanderson Kleber; Croda, Julio; Albuquerque, Carlos Frederico Campelo de; Nunes, Márcio Roberto Teixeira; Sabino, Ester Cerdeira; Loman, Nicholas; Naveca, Felipe Gomes; Pybus, Oliver G; Alcantara, Luiz Carlos Júnior (Elsevier, 2020)
      Zika virus (ZIKV) has caused an explosive epidemic linked to severe clinical outcomes in the Americas. As of June 2018, 4,929 ZIKV suspected infections and 46 congenital syndrome cases had been reported in Manaus, Amazonas, ...
    • Genomic and phylogenetic characterization of brazilian yellow fever virus strains 

      Nunes, Márcio Roberto Teixeira; Palacios, Gustavo; Cardoso, Jedson Ferreira; Martins, Lívia Caricio; Sousa Junior, Edivaldo C; Lima, Clayton P. S. de; Medeiros, Daniele Barbosa de Almeida; Savji, Nazir; Desai, Aaloki; Rodrigues, Sueli Guerreiro; Carvalho, Valéria Lima; Lipkin, W. Ian (American Society for Microbiology, 2012)
      Globally, yellow fever virus infects nearly 200,000 people, leading to 30,000 deaths annually. Although the virus is endemic to Latin America, only a single genome from this region has been sequenced. Here, we report 12 ...
    • Genomic characterization and evolution of Tacaiuma orthobunyavirus (Peribunyaviridae family) isolated in Brazil 

      Melo Junior, Aristides Bezerra de; Souza, William Marciel de; Acrani, Gustavo Olszanski; Carvalho, Valéria Lima; Romeiro, Marilia Farignoli; Tolardo, Aline Lavado; Silva, Sandro Patroca da; Cardoso, Jedson Ferreira; Chiang, Jannifer Oliveira; Vianez Júnior, João Lídio da Silva Gonçalves; Azevedo, Raimunda do Socorro da Silva; Figueiredo, Luiz Tadeu Moraes; Vasconcelos, Pedro Fernando da Costa; Nunes, Márcio Roberto Teixeira; Medeiros, Daniele Barbosa de Almeida (Elsevier, 2018)
      Tacaiuma virus (TCMV) is antigenically characterized as a member of the Anopheles A complex in the Orthobunyavirus genus, Peribunyaviridae family (Bunyavirales order). Clinically, the TCMV infection is characterized by ...
    • Genomic characterization of orthobunyavirus of veterinary importance in America 

      Tauro, Laura B.; Souza, William Marciel de; Rivarola, Maria Elisa; Oliveira, Rodrigo de; Konigheim, Brenda; Silva, Sandro Patroca da; Lima, Clayton; Oliveira, Layanna; Vasconcelos, Janaina M; Cardoso, Jedson Ferreira; Vianez Júnior, João Lídio da Silva Gonçalves; Nunes, Márcio Roberto Teixeira; Contigiani, Marta S (Elsevier, 2019)
      During 2013, in Argentina, three new isolates of serogroup Bunyamwera virus (genus Orthobunyavirus, family Peribunyaviridae) were recovered from two horses with encephalitis, and from an aborted equine fetus. In the present ...
    • Genomic screening of new putative antiviral lectins from Amazonian cyanobacteria based on a bioinformatics approach 

      Siqueira, Andrei Santos; Lima, Alex Ranieri Jerônimo; Aguiar, Délia Cristina Figueira; Santos, Alberdan Silva; Vianez Júnior, João Lídio da Silva Gonçalves; Gonçalves, Evonnildo Costa (Wiley, 2018)
      Lectins are proteins of nonimmune origin, which are capable of recognizing and binding to glycoconjugate moieties. Some of them can block the interaction of viral glycoproteins to the host cell receptors acting as antiviral ...
    • Genomic, epidemiological and digital surveillance of Chikungunya virus in the Brazilian Amazon 

      Navega, Felipe Gomes; Claro, Ingra Morales; Giovanetti, Marta; Jesus, Jaqueline Goes de; Xavier, Joilson; Iani, Felipe Campos de Melo; Nascimento, Valdinete Alves do; Souza, Victor Costa de; Silveira, Paola Paz; Lourenço, José; Santillana, Mauricio; Kraemer, Moritz U. G; Quick, Josh; Hill, Sarah C; Thézé, Julien; Carvalho, Rodrigo Dias de Oliveira; Azevedo, Vasco; Salles, Flavia Cristina da Silva; Nunes, Márcio Roberto Teixeira; Lemos, Poliana da Silva; Candido, Darlan da Silva; Pereira, Glauco de Carvalho; Oliveira, Marluce Aparecida Assunção; Meneses, Cátia Alexandra Ribeiro; Maito, Rodrigo Melo; Cunha, Claudeth Rocha Santa Brígida; Campos, Daniela Palha de Sousa; Castilho, Marcia da Costa; Siqueira, Thalita Caroline da Silva; Terra, Tiza Matos; Albuquerque, Carlos Frederico Campelo de; Cruz, Laura Nogueira da; Abreu, André Luiz de; Martins, Divino Valerio; Simões, Daniele Silva de Moraes Vanlume; Aguiar, Renato Santana de; Luz, Sérgio Luiz Bessa; Loman, Nicholas; Pybus, Oliver G; Sabino, Ester Cerdeira; Okumoto, Osnei; Alcantara, Luiz Carlos Júnior; Faria, Nuno Rodrigues (Public Library of Science, 2019)
      Background: Since its first detection in the Caribbean in late 2013, chikungunya virus (CHIKV) has affected 51 countries in the Americas. The CHIKV epidemic in the Americas was caused by the CHIKV-Asian genotype. In August ...
    • High genomic variability in equine infectious anemia virus obtained from naturally infected horses in Pantanal, Brazil: an endemic region case 

      Malossi, Camila Dantas; Fioratti, Eduardo Gorzoni; Cardoso, Jedson Ferreira; Magro, Angelo José; Kroon, Erna Geessien; Aguiar, Daniel Moura de; Borges, Alice Mamede Costa Marques; Nogueira, Marcia Furlan; Ullmann, Leila Sabrina; Araujo Jr, João Pessoa (MDPI, 2020)
      Abstract: Equine infectious anemia virus (EIAV) is a persistent lentivirus that causes equine infectious anemia (EIA). In Brazil, EIAV is endemic in the Pantanal region, and euthanasia is not mandatory in this area. All ...