• Genetic characterization of the Patois Serogroup (Genus Orthobunyavirus; Family Peribunyaviridae) and evidence that Estero Real Virus is a member of the Genus Orthonairovirus 

      Aguilar, Patricia V; Souza, William Marciel de; Silvas, Jesus A; Wood, Thomas; Widen, Steven; Fumagalli, Marcílio Jorge; Nunes, Márcio Roberto Teixeira (American Society of Tropical Medicine and Hygiene, 2018)
      Estero Real virus (ERV) was isolated in 1980 from Ornithodoros tadaridae ticks collected in El Estero Real, Sancti Spiritus, Cuba. Antigenic characterization of the isolate based on serological methods found a relationship ...
    • Genetic diversity of Hepatozoon spp. in Hydrochoerus hydrochaeris and Pecari tajacu from eastern Amazon 

      Gomes, Laise de Azevedo; Moraes, Leopoldo Augusto; Aguiar, Délia Cristina Figueira; Dias, Hilma Lúcia Tavares; Ribeiro, Ana Silvia Sardinha; Rocha, Henrique Piram do Couto; Nunes, Márcio Roberto Teixeira; Gonçalves, Evonnildo Costa (Elsevier, 2018)
      This study aimed to identify and characterize genetically species of the genus Hepatozoon detected in Hydrochoerus hydrochaeris (capybaras) and Pecari tajacu (collared peccaries) from two localities from the Eastern Amazon. ...
    • Genome sequence of chiqui virus, a novel reovirus isolated from mosquitoes collected in Colombia 

      Contreras-Gutiérrez, María Angélica; Guzman, Hilda; Cardoso, Jedson Ferreira; Popov, Vsevolod Leonidovich; Nunes, Márcio Roberto Teixeira; Uribe, Sandra; Widen, Steven G; Wood, Thomas G; Vasilakis, Nikos; Tesh, Robert B (American Society for Microbiology, 2018)
      We report here the complete genome sequence of a novel reovirus, designated Chiqui virus (CHQV) strain CoB38d, that was isolated from a pool of unidentified mosquitoes collected in northern Colombia in 2013. CHQV has ...
    • Genomic and epidemiological surveillance of Zika virus in the Amazon region 

      Giovanetti, Marta; Faria, Nuno Rodrigues; Lourenço, José; Jesus, Jaqueline Goes de; Xavier, Joilson; Claro, Ingra Morales; Kraemer, Moritz U. G; Fonseca, Vagner; Dellicour, Simon; Théze, Julien; Salles, Flavia da Silva; Graf, Tiago; Silveira, Paola Paz; Nascimento, Valdinete Alves do; Souza, Victor Costa de; Iani, Felipe Campos de Melo; Martins, Emerson Augusto Castilho; Cruz, Laura Nogueira; Wallau, Gabriel; Fabri, Allison; Levy, Flávia; Quick, Joshua; Azevedo, Vasco de; Aguiar, Renato Santana de; Oliveira, Tulio de; Menezes, Camila Bôtto de; Castilho, Marcia da Costa; Terra, Tirza Matos; Silva, Marineide Souza da; Filippis, Ana Maria Bispo de; Abreu, André Luiz de; Oliveira, Wanderson Kleber; Croda, Julio; Albuquerque, Carlos Frederico Campelo de; Nunes, Márcio Roberto Teixeira; Sabino, Ester Cerdeira; Loman, Nicholas; Naveca, Felipe Gomes; Pybus, Oliver G; Alcantara, Luiz Carlos Júnior (Elsevier, 2020)
      Zika virus (ZIKV) has caused an explosive epidemic linked to severe clinical outcomes in the Americas. As of June 2018, 4,929 ZIKV suspected infections and 46 congenital syndrome cases had been reported in Manaus, Amazonas, ...
    • Genomic and phylogenetic characterization of brazilian yellow fever virus strains 

      Nunes, Márcio Roberto Teixeira; Palacios, Gustavo; Cardoso, Jedson Ferreira; Martins, Lívia Caricio; Sousa Junior, Edivaldo C; Lima, Clayton P. S. de; Medeiros, Daniele Barbosa de Almeida; Savji, Nazir; Desai, Aaloki; Rodrigues, Sueli Guerreiro; Carvalho, Valéria Lima; Lipkin, W. Ian (American Society for Microbiology, 2012)
      Globally, yellow fever virus infects nearly 200,000 people, leading to 30,000 deaths annually. Although the virus is endemic to Latin America, only a single genome from this region has been sequenced. Here, we report 12 ...
    • Genomic characterization and evolution of Tacaiuma orthobunyavirus (Peribunyaviridae family) isolated in Brazil 

      Melo Junior, Aristides Bezerra de; Souza, William Marciel de; Acrani, Gustavo Olszanski; Carvalho, Valéria Lima; Romeiro, Marilia Farignoli; Tolardo, Aline Lavado; Silva, Sandro Patroca da; Cardoso, Jedson Ferreira; Chiang, Jannifer Oliveira; Vianez Júnior, João Lídio da Silva Gonçalves; Azevedo, Raimunda do Socorro da Silva; Figueiredo, Luiz Tadeu Moraes; Vasconcelos, Pedro Fernando da Costa; Nunes, Márcio Roberto Teixeira; Medeiros, Daniele Barbosa de Almeida (Elsevier, 2018)
      Tacaiuma virus (TCMV) is antigenically characterized as a member of the Anopheles A complex in the Orthobunyavirus genus, Peribunyaviridae family (Bunyavirales order). Clinically, the TCMV infection is characterized by ...
    • Genomic characterization of orthobunyavirus of veterinary importance in America 

      Tauro, Laura B.; Souza, William Marciel de; Rivarola, Maria Elisa; Oliveira, Rodrigo de; Konigheim, Brenda; Silva, Sandro Patroca da; Lima, Clayton; Oliveira, Layanna; Vasconcelos, Janaina M; Cardoso, Jedson Ferreira; Vianez Júnior, João Lídio da Silva Gonçalves; Nunes, Márcio Roberto Teixeira; Contigiani, Marta S (Elsevier, 2019)
      During 2013, in Argentina, three new isolates of serogroup Bunyamwera virus (genus Orthobunyavirus, family Peribunyaviridae) were recovered from two horses with encephalitis, and from an aborted equine fetus. In the present ...
    • Genomic screening of new putative antiviral lectins from Amazonian cyanobacteria based on a bioinformatics approach 

      Siqueira, Andrei Santos; Lima, Alex Ranieri Jerônimo; Aguiar, Délia Cristina Figueira; Santos, Alberdan Silva; Vianez Júnior, João Lídio da Silva Gonçalves; Gonçalves, Evonnildo Costa (Wiley, 2018)
      Lectins are proteins of nonimmune origin, which are capable of recognizing and binding to glycoconjugate moieties. Some of them can block the interaction of viral glycoproteins to the host cell receptors acting as antiviral ...
    • Genomic, epidemiological and digital surveillance of Chikungunya virus in the Brazilian Amazon 

      Navega, Felipe Gomes; Claro, Ingra Morales; Giovanetti, Marta; Jesus, Jaqueline Goes de; Xavier, Joilson; Iani, Felipe Campos de Melo; Nascimento, Valdinete Alves do; Souza, Victor Costa de; Silveira, Paola Paz; Lourenço, José; Santillana, Mauricio; Kraemer, Moritz U. G; Quick, Josh; Hill, Sarah C; Thézé, Julien; Carvalho, Rodrigo Dias de Oliveira; Azevedo, Vasco; Salles, Flavia Cristina da Silva; Nunes, Márcio Roberto Teixeira; Lemos, Poliana da Silva; Candido, Darlan da Silva; Pereira, Glauco de Carvalho; Oliveira, Marluce Aparecida Assunção; Meneses, Cátia Alexandra Ribeiro; Maito, Rodrigo Melo; Cunha, Claudeth Rocha Santa Brígida; Campos, Daniela Palha de Sousa; Castilho, Marcia da Costa; Siqueira, Thalita Caroline da Silva; Terra, Tiza Matos; Albuquerque, Carlos Frederico Campelo de; Cruz, Laura Nogueira da; Abreu, André Luiz de; Martins, Divino Valerio; Simões, Daniele Silva de Moraes Vanlume; Aguiar, Renato Santana de; Luz, Sérgio Luiz Bessa; Loman, Nicholas; Pybus, Oliver G; Sabino, Ester Cerdeira; Okumoto, Osnei; Alcantara, Luiz Carlos Júnior; Faria, Nuno Rodrigues (Public Library of Science, 2019)
      Background: Since its first detection in the Caribbean in late 2013, chikungunya virus (CHIKV) has affected 51 countries in the Americas. The CHIKV epidemic in the Americas was caused by the CHIKV-Asian genotype. In August ...
    • High genomic variability in equine infectious anemia virus obtained from naturally infected horses in Pantanal, Brazil: an endemic region case 

      Malossi, Camila Dantas; Fioratti, Eduardo Gorzoni; Cardoso, Jedson Ferreira; Magro, Angelo José; Kroon, Erna Geessien; Aguiar, Daniel Moura de; Borges, Alice Mamede Costa Marques; Nogueira, Marcia Furlan; Ullmann, Leila Sabrina; Araujo Jr, João Pessoa (MDPI, 2020)
      Abstract: Equine infectious anemia virus (EIAV) is a persistent lentivirus that causes equine infectious anemia (EIA). In Brazil, EIAV is endemic in the Pantanal region, and euthanasia is not mandatory in this area. All ...
    • Human pegivirus (HPgV, GBV-C) RNA in volunteer blood donors from a public hemotherapy service in Northern Brazil 

      Silva, Aniel de Sarom Negrão; Lima, Clayton Pereira Silva de; Barata, Rafael Ribeiro; Silva, Pedro Victor Reis da; Monteiro, Patricia Danin Jordão; Lamarão, Letícia; Burbano, Rommel Mário Rodrígues; Nunes, Márcio Roberto Teixeira; Lima, Danielle Lima de (BMC, 2020)
      Human pegivirus (HPgV)—formerly known as GBV-C—is a member of the Flaviviridae family and belongs to the species Pegivirus C. It is a non-pathogenic virus and is transmitted among humans mainly through the exposure to ...
    • ICTV virus taxonomy profile: Peribunyaviridae 

      Hughes, Holly R; Adkins, Scott; Alkhovskiy, Sergey V; Beer, Martin; Blair, Carol; Calisher, Charles H; Drebot, Mike; Lambert, Amy J; Souza, William Marciel de; Marklewitz, Marco; Nunes, Márcio Roberto Teixeira; Shi, Xiãohóng (Microbiology Society, 2020)
      Peribunyaviruses are enveloped and possess three distinct, single-stranded, negative-sense RNA segments comprising 11.2–12.5kb in total. The family includes globally distributed viruses in the genera Orthobunyavirus, ...
    • Identification and characterization of the expression profile of the microRNAs in the Amazon species Colossoma macropomum by next generation sequencing 

      Gomes, Fátima; Watanabe, Luciana; Nozawa, Sérgio; Oliveira, Layanna; Cardoso, Jedson Ferreira; Vianez Júnior, João Lídio da Silva Gonçalves; Nunes, Márcio Roberto Teixeira; Schneider, Horacio; Sampaio, Iracilda (Elsevier, 2017)
      Colossoma macropomum is a resistant species native of Amazonas and Orinoco river basins. It is regarded as the second largest finfish of Solimões and Amazon rivers, representing a major fishery resource in Amazonas and ...
    • Immune escape mutations in HIV-1 controllers in the Brazilian Amazon region 

      Gomes, Samara Tatielle Monteiro; Amoras, Ednelza da Silva Graça; Gomes, Érica Ribeiro; Queiroz, Maria Alice Freitas; Sousa Júnior, Edivaldo Costa; Massafra, Janaína Mota de Vasconcelos; Lemos, Poliana da Silva; Vianez Júnior, João Lídio da Silva Gonçalves; Vallinoto, Antonio Carlos Rosário (BMC, 2020)
      Background: Human immunodeficiency virus (HIV-1) infection is characterized by high viral replication and a decrease in CD4+ T cells (CD4+TC), resulting in AIDS, which can lead to death. In elite controllers and viremia ...
    • In silico analysis of the cyanobacterial lectin scytovirin : new insights into binding properties 

      Siqueira, Andrei Santos; Lima, Alex Ranieri Jerônimo; Souza, Rafael Conceição de; Santos, Alberdan Silva; Vianez Júnior, João Lídio da Silva Gonçalves; Gonçalves, Evonnildo Costa (Springer Verlag, 2017)
      Scytovirin is a lectin isolated from the cyanobacterium Scytonema varium that has shown activity against HIV, SARS coronavirus and Zaire Ebola virus. Its 95 amino acids are divided into two structural domains (SD), the ...
    • In silico improvement of the cyanobacterial lectin microvirin and mannose interaction 

      Lima, Adonis de Melo; Siqueira, Andrei Santos; Moller, Marina Luiza Saraiva; Souza, Rafael Conceição de; Cruz, Joddy Neves; Lima, Alex Ranieri Jerônimo; Silva, Ronaldo Correia da; Aguiar, Délia Cristina Figueira; Vianez Júnior, João Lídio da Silva Gonçalves; Gonçalves, Evonnildo Costa (Taylor & Francis, 2022)
      Lectins that bind to HIV envelope glycoprotein can inhibit virus-cell fusion and be used for rational drug design. This paper presents the results of anin silicoapproach to improve affinity interaction between the ...
    • Incidence of viral hepatitis in brazil from 2009 to 2018: an epidemiological study of confirmed cases of viral hepatitis 

      Silva, Alessandra Pereira da; Silva, Andressa Pereira; Souza, Lohana Marques Leal de; Peixoto, Natália de Oliveira; Gonçalves, Evonnildo Costa; Vianez Júnior, João Lídio da Silva Gonçalves (Sociedade Brasileira de Medicina Tropical, 2021)
      INTRODUCTION: Viral hepatitis is a major public health problem. It is necessary to understand the epidemic, verifying the combination of biological and demographic characteristics. METHODS: This is an analytical ecological ...
    • Infecção oculta pelo vírus da hepatite B em comunidade amazônica submetida a intenso fluxo migratório, estado do Pará, Brasil 

      Nunes, Heloisa Marceliano; Soares, Manoel do Carmo Pereira; Sarmento, Vânia Pinto; Malheiros, Andreza Pinheiro; Nunes, Márcio Roberto Teixeira (Instituto Evandro Chagas, 2017)
      INTRODUÇÃO: A infecção oculta pelo vírus da hepatite B – VHB (IOB) é definida como a presença do VHB-DNA no fígado, que pode ou não ser detectada no soro com HBsAg–, e suas possíveis implicações clínicas. OBJETIVO: Investigar ...
    • Insect-specific viruses and arboviruses in adult male culicids from Midwestern Brazil 

      Ferreira, Raquel da Silva; Cruz, Lucinéia Claudia de Toni Aquino da; Souza, Vilma Jucineide; Neves, Nilvanei Aparecido da Silva; Souza, Victor Costa de; Franco Filho, Luciano Chaves; Lemos, Poliana da Silva; Lima, Clayton Pereira Silva de; Naveca, Felipe Gomes; Atanaka, Marina; Nunes, Márcio Roberto Teixeira; Slhessarenko, Renata Dezengrini (Elsevier, 2020)
      Viruses were identified from male anthropophilic mosquitoes from Mato Grosso (MT) State, Midwest Brazil from February 2017 to January 2018. Mosquitoes tested included Aedes (Stegomyia) aegypti (1139 males; 84 pools), Culex ...
    • Insights into Limnothrix sp. metabolism based on comparative genomics 

      Lima, Alex Ranieri Jerônimo; Siqueira, Andrei Santos; Vasconcelos, Janaina Mota de; Pereira, James Siqueira; Azevedo, Juliana Simão Nina de; Moraes, Pablo Henrique Gonçalves; Aguiar, Délia Cristina Figueira; Lima, Clayton Pereira Silva de; Vianez Júnior, João Lídio da Silva Gonçalves; Nunes, Márcio Roberto Teixeira; Xavier, Luciana Pereira; Dall’Agnol, Leonardo Teixeira; Gonçalves, Evonnildo Costa (Frontiers Media, 2018)
      Currently only four genome sequences for Limnothrix spp. are publicly available, and information on the genetic properties of cyanobacteria belonging to this genus is limited. In this study, we report the draft genome ...