• High genomic variability in equine infectious anemia virus obtained from naturally infected horses in Pantanal, Brazil: an endemic region case 

      Malossi, Camila Dantas; Fioratti, Eduardo Gorzoni; Cardoso, Jedson Ferreira; Magro, Angelo José; Kroon, Erna Geessien; Aguiar, Daniel Moura de; Borges, Alice Mamede Costa Marques; Nogueira, Marcia Furlan; Ullmann, Leila Sabrina; Araujo Jr, João Pessoa (MDPI, 2020)
      Abstract: Equine infectious anemia virus (EIAV) is a persistent lentivirus that causes equine infectious anemia (EIA). In Brazil, EIAV is endemic in the Pantanal region, and euthanasia is not mandatory in this area. All ...
    • Human pegivirus (HPgV, GBV-C) RNA in volunteer blood donors from a public hemotherapy service in Northern Brazil 

      Silva, Aniel de Sarom Negrão; Lima, Clayton Pereira Silva de; Barata, Rafael Ribeiro; Silva, Pedro Victor Reis da; Monteiro, Patricia Danin Jordão; Lamarão, Letícia; Burbano, Rommel Mário Rodrígues; Nunes, Márcio Roberto Teixeira; Lima, Danielle Lima de (BMC, 2020)
      Human pegivirus (HPgV)—formerly known as GBV-C—is a member of the Flaviviridae family and belongs to the species Pegivirus C. It is a non-pathogenic virus and is transmitted among humans mainly through the exposure to ...
    • ICTV virus taxonomy profile: Peribunyaviridae 

      Hughes, Holly R; Adkins, Scott; Alkhovskiy, Sergey V; Beer, Martin; Blair, Carol; Calisher, Charles H; Drebot, Mike; Lambert, Amy J; Souza, William Marciel de; Marklewitz, Marco; Nunes, Márcio Roberto Teixeira; Shi, Xiãohóng (Microbiology Society, 2020)
      Peribunyaviruses are enveloped and possess three distinct, single-stranded, negative-sense RNA segments comprising 11.2–12.5kb in total. The family includes globally distributed viruses in the genera Orthobunyavirus, ...
    • Identification and characterization of the expression profile of the microRNAs in the Amazon species Colossoma macropomum by next generation sequencing 

      Gomes, Fátima; Watanabe, Luciana; Nozawa, Sérgio; Oliveira, Layanna; Cardoso, Jedson Ferreira; Vianez Júnior, João Lídio da Silva Gonçalves; Nunes, Márcio Roberto Teixeira; Schneider, Horacio; Sampaio, Iracilda (Elsevier, 2017)
      Colossoma macropomum is a resistant species native of Amazonas and Orinoco river basins. It is regarded as the second largest finfish of Solimões and Amazon rivers, representing a major fishery resource in Amazonas and ...
    • Immune escape mutations in HIV-1 controllers in the Brazilian Amazon region 

      Gomes, Samara Tatielle Monteiro; Amoras, Ednelza da Silva Graça; Gomes, Érica Ribeiro; Queiroz, Maria Alice Freitas; Sousa Júnior, Edivaldo Costa; Massafra, Janaína Mota de Vasconcelos; Lemos, Poliana da Silva; Vianez Júnior, João Lídio da Silva Gonçalves; Vallinoto, Antonio Carlos Rosário (BMC, 2020)
      Background: Human immunodeficiency virus (HIV-1) infection is characterized by high viral replication and a decrease in CD4+ T cells (CD4+TC), resulting in AIDS, which can lead to death. In elite controllers and viremia ...
    • In silico analysis of the cyanobacterial lectin scytovirin : new insights into binding properties 

      Siqueira, Andrei Santos; Lima, Alex Ranieri Jerônimo; Souza, Rafael Conceição de; Santos, Alberdan Silva; Vianez Júnior, João Lídio da Silva Gonçalves; Gonçalves, Evonnildo Costa (Springer Verlag, 2017)
      Scytovirin is a lectin isolated from the cyanobacterium Scytonema varium that has shown activity against HIV, SARS coronavirus and Zaire Ebola virus. Its 95 amino acids are divided into two structural domains (SD), the ...
    • In silico improvement of the cyanobacterial lectin microvirin and mannose interaction 

      Lima, Adonis de Melo; Siqueira, Andrei Santos; Moller, Marina Luiza Saraiva; Souza, Rafael Conceição de; Cruz, Joddy Neves; Lima, Alex Ranieri Jerônimo; Silva, Ronaldo Correia da; Aguiar, Délia Cristina Figueira; Vianez Júnior, João Lídio da Silva Gonçalves; Gonçalves, Evonnildo Costa (Taylor & Francis, 2022)
      Lectins that bind to HIV envelope glycoprotein can inhibit virus-cell fusion and be used for rational drug design. This paper presents the results of anin silicoapproach to improve affinity interaction between the ...
    • Incidence of viral hepatitis in brazil from 2009 to 2018: an epidemiological study of confirmed cases of viral hepatitis 

      Silva, Alessandra Pereira da; Silva, Andressa Pereira; Souza, Lohana Marques Leal de; Peixoto, Natália de Oliveira; Gonçalves, Evonnildo Costa; Vianez Júnior, João Lídio da Silva Gonçalves (Sociedade Brasileira de Medicina Tropical, 2021)
      INTRODUCTION: Viral hepatitis is a major public health problem. It is necessary to understand the epidemic, verifying the combination of biological and demographic characteristics. METHODS: This is an analytical ecological ...
    • Infecção oculta pelo vírus da hepatite B em comunidade amazônica submetida a intenso fluxo migratório, estado do Pará, Brasil 

      Nunes, Heloisa Marceliano; Soares, Manoel do Carmo Pereira; Sarmento, Vânia Pinto; Malheiros, Andreza Pinheiro; Nunes, Márcio Roberto Teixeira (Instituto Evandro Chagas, 2017)
      INTRODUÇÃO: A infecção oculta pelo vírus da hepatite B – VHB (IOB) é definida como a presença do VHB-DNA no fígado, que pode ou não ser detectada no soro com HBsAg–, e suas possíveis implicações clínicas. OBJETIVO: Investigar ...
    • Insect-specific viruses and arboviruses in adult male culicids from Midwestern Brazil 

      Ferreira, Raquel da Silva; Cruz, Lucinéia Claudia de Toni Aquino da; Souza, Vilma Jucineide; Neves, Nilvanei Aparecido da Silva; Souza, Victor Costa de; Franco Filho, Luciano Chaves; Lemos, Poliana da Silva; Lima, Clayton Pereira Silva de; Naveca, Felipe Gomes; Atanaka, Marina; Nunes, Márcio Roberto Teixeira; Slhessarenko, Renata Dezengrini (Elsevier, 2020)
      Viruses were identified from male anthropophilic mosquitoes from Mato Grosso (MT) State, Midwest Brazil from February 2017 to January 2018. Mosquitoes tested included Aedes (Stegomyia) aegypti (1139 males; 84 pools), Culex ...
    • Insights into Limnothrix sp. metabolism based on comparative genomics 

      Lima, Alex Ranieri Jerônimo; Siqueira, Andrei Santos; Vasconcelos, Janaina Mota de; Pereira, James Siqueira; Azevedo, Juliana Simão Nina de; Moraes, Pablo Henrique Gonçalves; Aguiar, Délia Cristina Figueira; Lima, Clayton Pereira Silva de; Vianez Júnior, João Lídio da Silva Gonçalves; Nunes, Márcio Roberto Teixeira; Xavier, Luciana Pereira; Dall’Agnol, Leonardo Teixeira; Gonçalves, Evonnildo Costa (Frontiers Media, 2018)
      Currently only four genome sequences for Limnothrix spp. are publicly available, and information on the genetic properties of cyanobacteria belonging to this genus is limited. In this study, we report the draft genome ...
    • Investigating the effects of point mutations on the affinity between the cyanobacterial lectin microvirin and high mannose-type glycans present on the HIV envelope glycoprotein 

      Souza, Rafael Conceição de; Muniz, Gabriela de Medeiros; Siqueira, Andrei santos; Lima, Adonis de Melo; Silva, Alessandra Pereira da; Gonçalves, Evonnildo Costa; Vianez Júnior, João Lídio da Silva Gonçalves (Springer Verlag, 2016)
      Human immunodeficiency virus (HIV) infections continue to exert an enormous impact on global human health. This led experts to emphasize the importance of new measures for preventing HIV infections, including the development ...
    • Isolation and genetic identification of endophytic lactic acid bacteria from the Amazonian Açai fruits: probiotics features of selected strains and their potential to inhibit pathogens 

      Sato, Suenne Taynah Abe; Marques, Joana Montezano; Freitas, André da Luz de; Progênio, Raphaela Cristina Sanches; Nunes, Márcio Roberto Teixeira; Massafra, Janaína Mota de Vasconcelos; Moura, Fábio Gomes; Rogez, Hervé (Frontiers Media, 2021)
      The açai palm (Euterpe oleracea) is native to the Amazon basin, a humid tropical forest. High levels of total mesophilic bacteria with high diversity have been consistently reported in açai fruits. As local consumers have ...
    • Low prevalence of HIV-1 integrase resistance among antiretroviral-naive patients newly diagnosed with HIV-1 from Belém, Pará, Amazon region of Brazil 

      Torres, Maria K. S; Avelino, Maria E. S; Irias, Susan F; Barbosa, Mike S; Pereira, Danilo L. A; Lima, Ana B. F; Lemos, Poliana da Silva; Lima, Clayton Pereira Silva de; Oliveira, Renato R. M; Frânces, Regiane S. K; Vianez Júnior, João Lídio da Silva Gonçalves; Machado, Luiz Fernando Almeida (Mary Ann Liebert, 2020)
      We described the HIV-1 subtypes and the frequency of resistance mutations in HIV-1 integrase region among antiretroviral-naive patients with HIV/AIDS from Belém, Pará, Amazon region of Brazil. The partial integrase gene ...
    • Metagenomic analysis of samples from three bat species collected in the Amazon rain forest 

      Franco Filho, Luciano Chaves; Barata, Rafael Ribeiro; Cardoso, Jedson Ferreira; Massafra, Janaina Mota de Vasconcelos; Lemos, Poliana da Silva; Casseb, Lívia Medeiros Neves; Cruz, Ana Cecília Ribeiro; Nunes, Márcio Roberto Teixeira (American Society for Microbiology, 2019)
      We report here the sequencing of five microbiome samples collected from different bat species in the Amazon rain forest. All contigs matching virus sequences were assigned to members of the Retroviridae family, while the ...
    • Metallothionein expression and its influence on the in vitro biological behavior of mucoepidermoid carcinoma 

      Aquime, João Rafael Habib souza; Zampieri, Lara Carolina D'Araújo Pinto; Kataoka, MAria Sueli da Silva; Ribeiro, Nelson Antonio Bailão; Jaeger, Ruy Gastaldoni; Silva, Artur Luiz da; Ramos, Rommel Thiago Jucá; Alves Júnior, Sérgio de Melo; Pinheiro, João de Jesus Viana (MDPI, 2020)
      Mucoepidermoid carcinoma (MEC) is the most common tumor in the salivary glands, often presenting with recurrence and metastasis due to its high invasive capacity. Metallothionein (MT), a zinc storage protein that supplies ...
    • Mitochondrial genome sequencing and phylogeny of Haemagogus albomaculatus, Haemagogus leucocelaenus, Haemagogus spegazzinii, and Haemagogus tropicalis (Diptera: Culicidae) 

      Silva, Fábio Silva da; Cruz, Ana Cecília Ribeiro; Medeiros, Daniele Barbosa de Almeida; Silva, Sandro Patroca da; Nunes, Márcio Roberto Teixeira; Martins, Lívia Caricio; Chiang, Jannifer Oliveira; Lemos, Poliana da Silva; Cunha, Gabriel Muricy; Araujo, Renato Freitas de; Monteiro, Hamilton Antônio de Oliveira; Nunes Neto, Joaquim Pinto (Nature Research, 2020)
      The genus Haemagogus (Diptera: Culicidae) comprises species of great epidemiological relevance, involved in transmission cycles of the Yellow fever virus and other arboviruses in South America. So far, only Haemagogus ...
    • Mobile real-time surveillance of Zika virus in Brazil 

      Faria, Nuno Rodrigues; Sabino, Ester C; Nunes, Márcio Roberto Teixeira; Alcantara, Luiz Carlos Júnior; Loman, Nicholas J; Pybus, Oliver G (BioMed Central, 2016)
      The World Health Organization has declared Zika virus an international public health emergency. Knowledge of Zika virus genomic epidemiology is currently limited due to challenges in obtaining and processing samples ...
    • Molecular analysis reveals the diversity of Hepatozoon species naturally infecting domestic dogs in a northern region of Brazil 

      Gomes, Laise de Azevedo; Moraes, Pablo Henrique Gonçalves; Nascimento, Luciana de Cássia Silva do; O’Dwyer, Lucia Helena; Nunes, Márcio Roberto Teixeira; Rossi, Adriana dos Reis Ponce; Aguiar, Délia Cristina Figueira; Gonçalves, Evonnildo Costa (Elsevier, 2016)
      This study aimed to optimize molecular methods for detecting DNA of Hepatozoon spp. as well as identify the phylogenetic relationships of Hepatozoon strains naturally infecting domestic dogs in Belém, Pará, northern Brazil. ...
    • Molecular characterization of Babesia vogeli in dogs from Belém, northern Brazil 

      Moraes, Pablo Henrique Gonçalves; Rufino, C. P; Baraúna, A. R. F; Reis, T; Dall'Agnol, Leonardo Teixeira; Meneses, A. M. C; Aguiar, Délia Cristina Figueira; Nunes, Márcio Roberto Teixeira; Gonçalves, Evonnildo Costa (Funpec-Rp, 2015)
      Babesiosis is an infectious hemolytic disease that occurs worldwide, and is caused by a protozoan of the Babesia genus (Apicomplexa). Little is known about this genus; therefore, this study conducted a molecular characterization ...