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Study of TNF-α, IFN-γ, TGF-β, IL-6, and IL-10 gene polymorphism in individuals from the leprosy endemic area in the Brazilian Amazon

Santos, Everaldina Cordeiro dos; Machado, Ricardo Luiz Dantas; Paz, Jasna Letícia; Silvestre, Maria do Perpétuo Socorro Corrêa Amador; Lima, Karla Valéria Batista; Lima, Luana Nepomuceno Gondim Costa (Elsevier, 2020)

This study aimed to verify the relationship between the polymorphisms of the cytokines TNF-α rs1800629; IFN-γ rs2430561; TGF-β rs1982073 e rs1800471; IL-6 rs180079 e IL-10 rs1800896, rs1800871 and rs1800872 and leprosy. ...

Association of the polymorphism of the vitamin D receptor gene (VDR) with the risk of leprosy in the Brazilian Amazon

Paz, Jasna Letícia Pinto; Silvestre, Maria do Perpétuo Socorro Corrêa Amador; Moura, Letícia Siqueira; Furlaneto, Ismari Perini; Rodrigues, Yan Corrêa; Lima, Karla Valéria Batista; Lima, Luana Nepomuceno Gondim Costa (Portland Press, 2021)

The transmission and evolution of leprosy depends on several aspects, including immunological and genetic factors of the host, as well as genetic factors of Mycobacterium leprae. The present study evaluated the association ...