Serological and molecular retrospective analysis of hepatitis E suspected cases from the Eastern Brazilian Amazon 1993-2014

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2019
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http://patua.iec.gov.br//handle/iec/3717
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Souza, Alex Junior Souza de
Malheiros, Andreza Pinheiro
Sarmento, Vânia Pinto
Resende, Fabricio de Souza
Alves, Max Moreira
Nunes, Heloisa Marceliano
Soares, Manoel do Carmo Pereira
Sá, Lilian Rose Marques de
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Introduction: We evaluated the anti-hepatitis E virus (HEV) antibody prevalence and HEV-RNA in archived serum samples of non-A–C hepatitis, or suspected cases of HEV infection from the Eastern Brazilian Amazon from 1993 to 2014. Methods: Serum samples (n = 318) were tested using ELISA and immunoblotting, and screened for HEV-RNA by RT-qPCR. Results: Anti-HEV IgM and IgG were detected in 3.4% (11/318) and 5.9% (19/318) of the samples, respectively. All samples were HEV-RNA negative. Conclusions: HEV was detected at a low prevalence. Broader serological and molecular evaluation of HEV infection in the Amazon region should be carried out.
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SOUZA, Alex Junior Souza de et al. Serological and molecular retrospective analysis of hepatitis E suspected cases from the Eastern Brazilian Amazon 1993-2014. Revista da Sociedade Brasileira de Medicina Tropical, v. 52, e20180465, p. 1-4, Apr. 2019.
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Hepatite E / patologia
Hepatite E / epidemiologia
Sorologia / métodos
Vírus de Hepatite
Amazônia Oriental Brasileira
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Acesso Aberto
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