• The spread of ndm-1 and ndm-7-producing Klebsiella pneumoniae is driven by multiclonal expansion of high-risk clones in healthcare institutions in the state of Pará, Brazilian Amazon Region 

  Rodrigues, Yan Corrêa; Lobato, Amália Raiana Fonseca; Quaresma, Ana Judith Pires Garcia; Guerra, Lívia Maria Guimarães Dutra; Brasiliense, Danielle Murici (MDPI, 2021)

  Carbapenem resistance among Klebsiella pneumoniae isolates is often related to carbapenemase genes, located in genetic transmissible elements, particularly the blaKPC gene, which variants are spread in several countries. ...

• Chemical composition and antifungal activity of myrcia multiflora and eugenia florida essential oils 

  Ferreira, Oberdan Oliveira; Silva, Silvia Helena Marques da; Oliveira, Mozaniel Santana de; Andrade, Eloisa Helena de Aguiar (MDPI, 2021)

  The essential oils of three specimens of Myrcia multiflora (A, B and C) and Eugenia florida were extracted by hydrodistillation, and the chemical compositions from the essential oils were identified by gas chromatography ...

• Risk factors associated with the severity of COVID-19 in a region of the Brazilian Amazon 

  Sardinha, Daniele Melo; Loiola, Rosane do Socorro Pompeu de; Ferreira, Ana Lúcia da Silva; Sá, Carmem Aliandra Freire de; Rodrigues, Yan Corrêa; Lima, Karla Valéria Batista; Guimarães, Ricardo José de Paula Souza e; Lima, Luana Nepomuceno Gondim Costa (Nature Research, 2021)

  The Brazilian Northern region registered a high incidence of COVID-19 cases, particularly in the state of Pará. The present study investigated the risk factors associated with the severity of COVID-19 in a Brazilian Amazon ...

• Population prevalence of trachoma in nine rural non-indigenous evaluation units of Brazil 

  Szwarcwald, Célia Landmann; Lopes, Maria de Fátima Costa; Souza Junior, Paulo Roberto Borges de; Gómez, Daniela Vaz Ferreira; Luna, Expedito José de Albuquerque; Almeida, Wanessa da Silva de; Damacena, Giseli Nogueira; Favacho, Joana da Felicidade Ribeiro; Frias, Paulo Germano de; Butcher, Robert; Boyd, Sarah; Bakhtiari, Ana; Willis, Rebecca; Jimenez, Cristina; Harding-Esch, Emma; Saboyá-Díaz, Martha Idalí; Solomon, Anthony W (Taylor & Francis, 2021)

  Purpose: To assess the contemporary prevalence of trachoma in Brazil’s non-indigenous population, surveys of those thought to be at greatest risk of disease were conducted. Methods: Rural census tracts of non-indigenous ...

• Whole-genome sequencing of alcaligenes faecalis HZ01, with potential to inhibit nontuberculous mycobacterial growth 

  Fernandes, Henry Marcel Zolona; Conceição, Emilyn Costa; Silva, Sandro Patroca da; Machado, Edson; Sisco, Maria Carolina; Sharma, Abhinav; Lima, Karla Valéria Batista; Conceição, Marília Lima da; Carvalho, Ana Carolina da Silva; Miranda, Karla Rodrigues; Duarte, Rafael Silva; Alviano, Daniela Sales; Dias, Rubens Clayton da Silva (American Society for Microbiology, 2021)

  Alcaligenes faecalis is a Gram-negative rod that is ubiquitous in the environment and is an opportunistic human pathogen. Here, we report the whole-genome sequencing analysis of A. faecalis HZ01, which presents mycobacterial ...

• Socio-epidemiological features and spatial distribution of Malaria in an area under mining activity in the Brazilian Amazon Region 

  Ueno, Thalyta Mariany Rêgo Lopes; Lima, Luana Nepomuceno Gondim Costa; Sardinha, Daniele Melo; Rodrigues, Yan Corrêa; Souza, Herberto Ueno Seelig de; Teixeira, Paula Ribeiro; Guimarães, Ricardo José de Paula Souza e; Lima, Karla Valéria Batista; Ventura, Ana Maria Revorêdo da Silva (MDPI, 2021)

  Abstract: Malaria is an acute febrile infectious disease that represents an important public health problem in the Brazilian amazon region. The present study described the socio-epidemiological and spatial characteristics ...

• Análise retrospectiva de casos de tuberculose em idosos 

  Mesquita, Cristal Ribeiro; Lima, Karla Valéria Batista; Guimarães, Ricardo José de Paula Souza e; Santos, Bruno de Oliveira; Rodrigues, Luis Henrique Almeida; Costa, Rodrigo Junior Farias da; Santos, Brenda do Socorro de Oliveira; Iúdice, Tirça Naiara da Silva (Universidade de Fortaleza, 2021)

  Objetivo: Relatar o perfil sociodemográfico e clínico epidemiológico de idosos portadores de tuberculose (TB) em uma capital do Norte do Brasil. Métodos: Estudo retrospectivo, de caráter descritivo, transversal e quantitativo, ...

• Analysis of 472,688 severe cases of COVID-19 in Brazil showed lower mortality in those vaccinated against Influenza 

  Sardinha, Daniele Melo; Lobato, Diana da Costa; Ferreira, Ana Lúcia da Silva; Lima, Karla Valéria Batista; Guimarães, Ricardo José de Paula Souza e; Lima, Luana Nepomuceno Gondim Costa (Scientific Research Publishing, 2021)

  Objective: To analyze the severe cases of COVID-19 in Brazil in 2020 and compare those vaccinated and unvaccinated against influenza in invasive ventilation, admission in Intensive Care Unit (ICU) and deaths. ...

• Association of the polymorphism of the vitamin D receptor gene (VDR) with the risk of leprosy in the Brazilian Amazon 

  Paz, Jasna Letícia Pinto; Silvestre, Maria do Perpétuo Socorro Corrêa Amador; Moura, Letícia Siqueira; Furlaneto, Ismari Perini; Rodrigues, Yan Corrêa; Lima, Karla Valéria Batista; Lima, Luana Nepomuceno Gondim Costa (Portland Press, 2021)

  The transmission and evolution of leprosy depends on several aspects, including immunological and genetic factors of the host, as well as genetic factors of Mycobacterium leprae. The present study evaluated the association ...

• Bovine tuberculosis due to Mycobacterium bovis and other mycobacteria among water buffalo (Bubalus bubalis) from the Brazilian Amazon 

  Pedroso, Silvia Cristina da Silva; Lima, Karla Valéria Batista; Furlaneto, Ismari Perini; Rodrigues, Yan Corrêa; Pantoja, Darlene Kássia Saraiva Queiroz; Souza, Alex Junior Souza de; Pereira, Washington Luiz Assunção (2021)

  Introduction: Zoonotic tuberculosis is a disease of public health importance worldwide, especially in developing countries. The present study aimed to investigate the role played by Mycobacterium bovis and other mycobacteria ...

• Genome-wide scans for leprosy and tuberculosis susceptibility genes in Brazilians 

  Miller, E. N; Jamieson, S. E; Joberty, C; Fakiola, M; Hudson, D; Peacock, C. S; Cordell, H. J; Shaw, M. A; Lainson, Zéa Constante Lins; Shaw, Jeffrey Jon; Ramos, Francisco Lúzio de Paula; Silveira, Fernando Tobias; Blackwell, J. M (Springer Nature, 2004)

  Genome-wide scans were conducted for tuberculosis and leprosy per se in Brazil. At stage 1, 405 markers (10cM map) were typed in 16 (178 individuals) tuberculosis and 21 (173 individuals) leprosy families. Nonparametric ...

• Virulence associated factors in bacteria from water bodies in Belem, Para, Brazil: bacteriological composition and threat to public health 

  Trindade, Lucas Monteiro da; Correa Filho, Luiz Claudio Gomes; Santos, Denise Suellen Amorim de Sousa; Sousa, Nayara Rufino; Vale, Elivam Rodrigues; Rocha, Daniela Cristiane da Cruz; Morais, Lena Líllian Canto de Sá (IWA Publishing, 2021)

  A lack of sewage treatment contaminates water bodies threatening human health by spreading waterborne gastroenteritis. This is a particular problem for developing countries, where the risks associated with surface water ...

• Syphilis in a mining region of the Brazilian Amazon: prevalence and characteristics 

  Ueno, Thalyta Mariany Rêgo Lopes; Gomes, Samara Tatielle Monteiro; Sousa, Maísa Silva de; Favacho, Joana da Felicidade Ribeiro; Lima, Luana Nepomuceno Gondim Costa; Sardinha, Daniele Melo; Rodrigues, Yan Corrêa; Guimarães, Ricardo José de Paula Souza e; Ventura, Ana Maria Revoredo da Silva; Lima, Karla Valéria Batista (2021)

  Syphilis is a chronic bacterial infection, being one of the main determinants of sexually transmitted infections (STIs). It is endemic in low-income countries, it is important for both individual and public health because, ...

• Occurrence of cardiovascular complications associated with SARS-CoV-2 infection: a systematic review 

  Sardinha, Daniele Melo; Lima, Karla Valéria Batista; Ueno, Thalyta Mariany Rêgo Lopes; Rodrigues, Yan Corrêa; Garcez, Juliana Conceição Dias; Santos, Anderson Lineu Siqueira dos; Ferreira, Ana Lúcia da Silva; Guimarães, Ricardo José de Paula Souza e; Lima, Luana Nepomuceno Gondim Costa (2021)

  Cardiovascular Diseases represent the main cause of death in the world, and are associated with risk factors that cause serious complications in cases of infections, such as those of the respiratory tract. In March 2020 ...

• Surgical site infection following caesarean section by acinetobacter species: a report fr om a hyperendemic setting in the brazilian amazon region 

  Cabral, Blenda Gonçalves; Brasiliense, Danielle Murici; Furlaneto, Ismari Perini; Rodrigues, Yan Corrêa; Lima, Karla Valéria Batista (MDPI, 2021)

  Surgical site infection (SSI) following caesarean section is associated with increased morbidity, mortality, and significant health care costs. This study evaluated the epidemiological, clinical, and microbiological features ...

• Molecular epidemiology of Mycobacterium tuberculosis in Brazil before the whole genome sequencing era: a literature review 

  Conceição, Emilyn Costa; Salvato, Richard Steiner; Gomes, Karen Machado; Guimarães, Arthur Emil dos Santos; Conceição, Marília Lima da; Guimarães, Ricardo José de Paula Souza e; Sharma, Abhinav; Furlaneto, Ismari Perini; Barcellos, Regina Bones; Bolleta, Valdes Roberto; Anselmo, Lívia Maria Pala; Sisco, Maria Carolina; Niero, Cristina Viana; Ferrazoli, Lucilaine; Refrégier, Guislaine; Lourenço, Maria Cristina da Silva; Gomes, Harrison Magdinier; Brito, Artemir Coelho de; Catanho, Marcos; Duarte, Rafael Silva; Suffys, Philip Noel; Lima, Karla Valéria Batista (Instituto Oswaldo Cruz, 2021)

  Molecular-typing can help in unraveling epidemiological scenarios and improvement for disease control strategies. A literature review of Mycobacterium tuberculosis transmission in Brazil through genotyping on 56 studies ...

• Local adaptation in populations of Mycobacterium tuberculosis endemic to the Indian Ocean Rim 

  Menardo, Fabrizio; Rutaihwa, Liliana K; Zwyer, Michaela; Borrell, Sonia; Comas, Iñaki; Conceição, Emilyn Costa; Cascolla, Mireia; Cox, Hellen; Joloba, Moses; Dou, Horng-Yunn; Feldmann, Julia; Fenner, Lukas; Fyfe, Janet; Gao, Qian; Viedma, Darío García de; Garcia-Basteiro, Alberto L; Gygli, Sebastian M; Hella, Jerry; Hiza, Hellen; Jugheli, Levan; Kamwela, Lujeko; Kato-Maeda, Midori; Liu, Qingyun; Ley, Serej D; Loiseau, Chloe; Mahasirimongkol, Surakameth; Malla, Bijaya; Palittapongarnpim, Prasit; Rakotosamimmanana, Niaina; Rasolofo, Voahangy; Reinhard, Miriam; Reither, Klaus; Sasamalo, Mohamed; Duarte, Rafael Silva; Sola, Christophe; Suffys, Philip; Lima, Karla Valéria Batista; Yeboah-Manu, Dorothy; Beisel, Christian; Brites, Daniela; Gagneux, Sebastien (2021)

  Lineage 1 (L1) and 3 (L3) are two lineages of the Mycobacterium tuberculosis complex (MTBC), causing tuberculosis (TB) in humans. L1 and L3 are endemic to the Rim of the Indian Ocean, the region that accounts for most of ...

• Outbreak of Acinetobacter colistiniresistens bloodstream infections in a neonatal intensive care unit 

  Brasiliense, Danielle; Cayô, Rodrigo; Streling, Ana Paula; Nodari, Carolina S; Souza, Cintya; Leal, Crislaine; Gales, Ana C (Elsevier, 2021)

• A clinical-epidemiological and geospatial study of tuberculosis in a neglected area in the amazonian region highlights the urgent need for control measures 

  Mesquita, Cristal Ribeiro; Conceição, Emilyn Costa; Monteiro, Lúcia Helena Martins Tavares; Silva, Odinea Maria da; Lima, Luana Nepomuceno Gondim Costa; Oliveira, Rafael Aleixo Coelho de; Brito, Artemir Coelho de; Guimarães, Ricardo José de Paula Souza e; Lima, Karla Valéria Batista (MDPI, 2021)

  Abstract: Tuberculosis (TB) is an infectious communicable disease, which despite global efforts, still needs special attention in regions with difficult access. This study aims to describe the spatial and epidemiological ...

• Supercritical CO2 extraction to obtain Lippia thymoides Mart. & Schauer (Verbenaceae) essential oil rich in thymol and evaluation of its antimicrobial activity 

  Silva, Sebastião Gomes; Oliveira, Mozaniel Santana de; Cruz, Jorddy Neves; Costa, Wanessa Almeida; Silva, Silvia Helena Marques da; Maia, Ana Aurea Barreto; Sousa, Ronaldo Lopes de; Carvalho Junior, Raul Nunes; Andrade, Eloisa Helena de Aguiar (Elsevier, 2021)

  In this paper, for the first time, the extraction of Lippia thymoides leaf essential oil (EO), by supercritical CO2, is reported. Extractions have been carried out at 40 and 50 °C, and 100, 200 and 300 bar. The mass yields ...

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