Sinu Virus, a novel and divergent orthomyxovirus related to members of the genus Thogotovirus isolated from mosquitoes in Colombia.
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2017xmlui.mirage2.itemSummaryView.MetaData
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http://patua.iec.gov.br//handle/iec/3856xmlui.dri2xhtml.METS-1.0.item-abstract
The genome and structural organization of a novel insect-specific orthomyxovirus, designated Sinu virus, is described. Sinu virus (SINUV) was isolated in cultures of C6/36 cells from a pool of mosquitoes collected in northwestern Colombia. The virus has six negative-sense ssRNA segments. Genetic analysis of each segment demonstrated the presence of six distinct ORFs encoding the following genes: PB2 (Segment 1), PB1, (Segment 2), PA protein (Segment 3), envelope GP gene (Segment 4), the NP (Segment 5), and M-like gene (Segment 6). Phylogenetically, SINUV appears to be most closed related to viruses in the genus Thogotovirus.
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CONTRERAS-GUTIÉRREZ, María Angélica et al. Sinu Virus, a novel and divergent orthomyxovirus related to members of the genus Thogotovirus isolated from mosquitoes in Colombia. Virology, v. 501, p. 166-175, 2017.xmlui.dri2xhtml.METS-1.0.item-decsPrimary
Culicidae / virologiaOrthomyxoviridae / classificação
Orthomyxoviridae / química
Orthomyxoviridae / genética
Orthomyxoviridae / isolamento & purificação
Orthomyxoviridae / ultraestrutura
Thogotovirus / classificação
Thogotovirus / química
Thogotovirus / genética
Thogotovirus / isolamento & purificação
Thogotovirus / ultraestrutura
Proteínas Virais / genética
Proteínas Virais / química
Proteínas Virais / metabolismo
Evolução Molecular
Modelos Moleculares
Genoma Viral
Sequência de Aminoácidos
Dados de Sequência Molecular
Técnica Indireta de Fluorescência para Anticorpo / Métodos
Reação em Cadeia da Polimerase Via Transcriptase Reversa / métodos