Effect of age and sex on bone markers in Chlorocebus aethiops raised in captivity
Imbeloni, Aline Amaral
Rahal, Sheila Canavese
Silva Filho, Ednaldo da
Faria, Bianca Mendonça
Silva, Wellington Bandeira da
Oliveira, Karol Guimarães
Aihara, Mika Ester
Monteiro, Frederico Ozanan Barros
The objective was to evaluate the procollagen type I N-propeptide (PINP), osteocalcin (OC), β-crosslaps (β-CTX), and parathyroid hormone (PTH) in relation to age and sex of Chlorocebus aethiops in captivity. METHODS: Seventy-three monkeys were divided into four age groups: AG1 (juvenile); AG2 (young adult); AG3 (adult); and AG4 (senile). An electrochemiluminescence immunoassay with an Elecsys 2010 analyzer was used to determine the serum markers of bone. RESULTS AND CONCLUSIONS: Sex did not influence the results of the markers. However, the variables PINP, OC, and β-CTX were negatively correlated with age (r = -0.643; r = -0.711; r = -0.488; P < 0.001, respectively), and PTH was correlated positively with age (r = 0.418, P < 0.001). The data obtained can be used as biomarkers of bone metabolism reference intervals in healthy C. aethiops in captivity.
xmlui.dri2xhtml.METS-1.0.item-citationIMBELONI, Aline Amaral et al. Effect of age and sex on bone markers in Chlorocebus aethiops raised in captivity. Journal of Medical Primatology, v. 45, n. 1, p. 3-11, Feb. 2016.
xmlui.dri2xhtml.METS-1.0.item-decsPrimaryPrimatas / anatomia & histologia
Cercopithecinae / anatomia & histologia
Biomarcadores / análise
Reabsorção Óssea / veterinária