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dc.contributor.authorAlmeida, Ariely Nunes Ferreira de-
dc.contributor.authorNascimento, Luciana de Cássia Silva do-
dc.contributor.authorSousa, Edith Silvia Moura de Moura-
dc.contributor.authorOliveira, Afonso José Diger de-
dc.contributor.authorSena, Maria Gorete de-
dc.contributor.authorResende, Breno Maués de-
dc.contributor.authorChaves, Raimunda Cleide Gonçalves-
dc.contributor.authorSantos, Lourdes Maria Garcez dos-
dc.date.accessioned2020-04-07T16:41:45Z-
dc.date.available2020-04-07T16:41:45Z-
dc.date.issued2020-
dc.identifier.citationALMEIDA, Ariely Nunes Ferreira de et al. Surveillance of cutaneous leishmaniasis in clinical samples: distribution of Leishmania guyanensis in the state of Amapá, Brazil, 2018. Epidemiologia e Serviços de Saúde, v. 29, n. 1, e2018504, 2020.pt_BR
dc.identifier.issn2237-9622-
dc.identifier.urihttp://patua.iec.gov.br//handle/iec/4082-
dc.description.abstractObjective: to investigate Leishmania species in a series of autochthonous cutaneous leishmaniasis (CL) cases in Amapá State, Brazilian Amazon. Methods: this was a descriptive ecological study carried out from January-October/2018 at a reference center for CL diagnosis in Amapá; individuals with CL receiving care from January-May/2018 were recruited; clinical data and skin biopsies were obtained; from extracted DNA (phenol-chloroform) we amplified the hsp70-234 gene region (PCR) for nucleotide sequencing (Applied Biosystems: ABI3500XL). Results: 38 individuals were interviewed, examined and diagnosed; men predominated (28/38; mean age=32.5±11.3); lesions (most ulcers: 37/38) measuring 0,4-10mm (34/38) and ≥11mm (4/38) were multiple in 20/38 individuals; diagnosis of L. braziliensis (1), L. naiffi (1), L. infantum (1), L. (Viannia) sp. (1), L. amazonensis (2) and L. guyanensis (32); individuals infected with L. guyanensis (32/38) lived in 9/10 municipalities represented in the sample, and 17/32 of these had multiple lesions. Conclusion: presence of Leishmania guyanensis predominated and was frequently associated with multiple lesions.pt_BR
dc.description.sponsorshipThis research received financial support from the Amapá State Research Support Foundation (FAPEAP) – Process No. 250.203.039/2016 – and a doctoral Research Grant from the Pará State Research Support Foundation (FAPESPA) – Process No. 003/2014.pt_BR
dc.language.isoengpt_BR
dc.publisherMinistério da Saúde. Secretaria de Vigilância em Saúdept_BR
dc.rightsAcesso Abertopt_BR
dc.titleSurveillance of cutaneous leishmaniasis in clinical samples: distribution of Leishmania guyanensis in the state of Amapá, Brazil, 2018pt_BR
dc.title.alternativeVigilância da leishmaniose cutânea em amostras clínicas: distribuição da Leishmania guyanensis no estado do Amapá, 2018pt_BR
dc.typeArtigopt_BR
dc.subject.decsPrimaryLeishmaniose Cutânea / patologiapt_BR
dc.subject.decsPrimaryLeishmania guyanensis / parasitologiapt_BR
dc.subject.decsPrimaryEpidemiologia Molecular / métodospt_BR
dc.subject.decsPrimaryEcossistema Amazônicopt_BR
dc.subject.decsPrimaryAmapá (AP)pt_BR
dc.creator.affilliationUniversidade Federal do Amapá. Departamento de Ciências Biológicas e da Saúde. Macapá, AP, Brasil.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.creator.affilliationSecretaria de Estado da Saúde. Centro de Referência em Doenças Tropicais. Macapá, AP, Brasil.pt_BR
dc.creator.affilliationSecretaria de Estado da Saúde. Centro de Referência em Doenças Tropicais. Macapá, AP, Brasil.pt_BR
dc.creator.affilliationSecretaria de Estado da Saúde. Centro de Referência em Doenças Tropicais. Macapá, AP, Brasil.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.creator.affilliationSuperintendência de Vigilância em Saúde. Unidade de Controle de Zoonoses. Macapá, AP, Brasil.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.identifier.doi10.5123/S1679-49742020000100007-


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