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dc.contributor.authorNormando, Valéria Marques Ferreira-
dc.contributor.authorDias, Ápio Ricardo Nazareth-
dc.contributor.authorSilva, André Luiz Saldanha Eremita da-
dc.contributor.authorPinto, Denise da Silva-
dc.contributor.authorSantos, Marcio Clementino de Souza-
dc.contributor.authorRodrigues, Caroline Lobato-
dc.contributor.authorOliveira, Ediléa Monteiro de-
dc.contributor.authorSouza Filho, Luiz Euclides Coelho de-
dc.contributor.authorVieira, Waldônio de Brito-
dc.contributor.authorAndriolo, Regis Bruni-
dc.contributor.authorSousa, Rita Catarina Medeiros-
dc.contributor.authorFalcão, Luiz Fábio Magno-
dc.contributor.authorQuaresma, Juarez Antônio Simões-
dc.date.accessioned2020-07-15T14:04:12Z-
dc.date.available2020-07-15T14:04:12Z-
dc.date.issued2020-
dc.identifier.citationNORMANDO, Valéria Marques Ferreira et al. HTLV-I induces lesions in the pulmonary system: a systematic review. Life Sciences, v. 256, n. 117979, p. xx, Sept. 2020.pt_BR
dc.identifier.issn1879-0631-
dc.identifier.urihttp://patua.iec.gov.br//handle/iec/4115-
dc.description.abstractThis study analyzed the relationship between infection by human T-cell lymphotropic virus type 1 (HTLV-1) and changes in the pulmonary system. Cohort and case-control study models that analyzed a causal association between HTLV-1 and changes in the pulmonary system were considered. There were no restrictions on language and publication period. The study was registered in the PROSPERO systematic analysis database (Protocol No. CRD42017078236) and was prepared according to the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. The following databases were used: PubMed, BVS Regional Portal, Embase, CINAHL and Web of Science. We utilized the Newcastle-Ottawa Scale to assess the methodological quality of published studies and the Kappa coefficient to assess the agreement level between two reviewers. Of the total 1156 studies retrieved by the search strategy, 28 were considered potentially eligible (Kappa test = 0.928). Of the 28 studies, three fully met the inclusion criteria. These indicated that pulmonary lesions, such as bronchiectasis and bronchitis/bronchiolitis, were observed in patients with HTLV-1, with high-resolution computed tomography of the chest being the main method of diagnostic investigation. The analyzed cohort and case-control studies indicated an etiological relationship between HTLV-1 infection and the presence of lung lesions, with emphasis on bronchiectasis in the presence of high viral loads, as well as a higher mortality in these individuals compared with the general population.pt_BR
dc.language.isoengpt_BR
dc.publisherElsevierpt_BR
dc.rightsAcesso Embargadopt_BR
dc.titleHTLV-I induces lesions in the pulmonary system: a systematic reviewpt_BR
dc.typeArtigopt_BR
dc.subject.decsPrimaryVírus Linfotrópico T Tipo 1 Humano / isolamento & purificaçãopt_BR
dc.subject.decsPrimaryDoenças Respiratórias / diagnóstico por imagempt_BR
dc.subject.decsPrimaryInfecções por HTLV-Ipt_BR
dc.subject.decsPrimaryLesão Pulmonarpt_BR
dc.subject.decsPrimaryMetanálisept_BR
dc.subject.decsPrimaryRevisões Sistemáticas como Assuntopt_BR
dc.creator.affilliationFederal University of Pará. Center for Tropical Medicine. Belém, PA, Brazil / State University of Pará. Center for Biological and Health Sciences. Belém, PA, Brazil.pt_BR
dc.creator.affilliationState University of Pará. Center for Biological and Health Sciences. Belém, PA, Brazil.pt_BR
dc.creator.affilliationFederal University of Pará. Center for Tropical Medicine. Belém, PA, Brazil.pt_BR
dc.creator.affilliationState University of Pará. Center for Biological and Health Sciences. Belém, PA, Brazil.pt_BR
dc.creator.affilliationState University of Pará. Center for Biological and Health Sciences. Belém, PA, Brazil.pt_BR
dc.creator.affilliationState University of Pará. Center for Biological and Health Sciences. Belém, PA, Brazil.pt_BR
dc.creator.affilliationState University of Pará. Center for Biological and Health Sciences. Belém, PA, Brazil.pt_BR
dc.creator.affilliationFederal University of Pará. Center for Tropical Medicine. Belém, PA, Brazil / Santa Casa de Misericórdia Foundation. Belém, PA, Brazil.pt_BR
dc.creator.affilliationState University of Pará. Center for Biological and Health Sciences. Belém, PA, Brazil.pt_BR
dc.creator.affilliationFederal University of Pará. Center for Tropical Medicine. Belém, PA, Brazil.pt_BR
dc.creator.affilliationState University of Pará. Center for Biological and Health Sciences. Belém, PA, Brazil.pt_BR
dc.creator.affilliationFederal University of Pará. Center for Tropical Medicine. Belém, PA, Brazil / State University of Pará. Center for Biological and Health Sciences. Belém, PA, Brazil / Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.identifier.doi10.1016/j.lfs.2020.117979-


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