xmlui.ArtifactBrowser.ItemViewer.show_simple

dc.contributor.authorBruneto, Eduardo G-
dc.contributor.authorFernandes-Silva, Miguel M-
dc.contributor.authorToledo-Cornell, Cristina-
dc.contributor.authorMartins, Silvia-
dc.contributor.authorFerreira, João M. B-
dc.contributor.authorCorrêa, Valeria R-
dc.contributor.authorCosta, Joicely M. da-
dc.contributor.authorPinto, Ana Yecê das Neves-
dc.contributor.authorSouza, Dilma do S. M. de-
dc.contributor.authorPinto, Maria Carmelinda G-
dc.contributor.authorF. Neto, José Albuquerque de-
dc.contributor.authorRamos Jr, Alberto N-
dc.contributor.authorMaguire, James H-
dc.contributor.authorSilvestre, Odilson M-
dc.date.accessioned2020-11-30T13:38:47Z-
dc.date.available2020-11-30T13:38:47Z-
dc.date.issued2021-
dc.identifier.citationBRUNETO, Eduardo G. et al. Case-fatality from orally-transmitted acute Chagas disease: a systematic review and metanalysis. Clinical Infectious Diseases, v. 72, n. 6, p. 1084-1092, Mar. 2021.pt_BR
dc.identifier.issn1537-6591-
dc.identifier.urihttp://patua.iec.gov.br//handle/iec/4204-
dc.description.abstractOrally-transmitted acute Chagas disease (CD) is emerging as an important public health problem. The prognosis of acute infection following oral transmission is unknown. The aim of this paper was to analyze and summarize data on orally-transmitted acute CD. We searched for studies from 1968 to January 31, 2018. We included studies and unpublished data from government sources that reported patients with acute CD orally-transmitted. We identified 41 papers and we added 932 unpublished cases. In all, our study covered 2470 cases and occurrence of 97 deaths. Our meta-analysis estimated that the case-fatality rate was 1.0% (95% CI 0.0 – 4.0%). Lethality rates have been declined over time (p = 0.02). In conclusion, orally-transmitted acute CD has considerable lethality in the first year after infection. The lethality in symptomatic cases is similar to that from other routes of infection. The lethality rate of orally-acquired disease have declined over the years.pt_BR
dc.language.isoengpt_BR
dc.publisherOxford University Presspt_BR
dc.rightsAcesso Embargadopt_BR
dc.titleCase-fatality from orally-transmitted acute Chagas disease: a systematic review and metanalysispt_BR
dc.typeArtigopt_BR
dc.subject.decsPrimaryDoença de Chagas / diagnósticopt_BR
dc.subject.decsPrimaryDoença de Chagas / transmissãopt_BR
dc.subject.decsPrimaryMucosa Bucalpt_BR
dc.subject.decsPrimaryMortalidade
dc.subject.decsPrimaryMetanálise como Assunto
dc.subject.decsPrimaryRevisões Sistemáticas como Assunto
dc.creator.affilliationFederal University of Acre. Rio Branco, AC, Brazil.pt_BR
dc.creator.affilliationFederal University of Parana. Curitiba, PR, Brazil.pt_BR
dc.creator.affilliationElson S. Floyd College of Medicine. Lumni Tribal Health Center. Spokane, WA, Estados Unidos.pt_BR
dc.creator.affilliationUniversity of Pernambuco. Recife, PE, Brazil.pt_BR
dc.creator.affilliationUniversity of Amazonas. Manaus, AM, Brazil.pt_BR
dc.creator.affilliationUniversity of Tocantins. Palmas, TO, Brazil.pt_BR
dc.creator.affilliationFederal University of Acre. Rio Branco, AC, Brazil.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.creator.affilliationFederal University of Pará. Medical School. Belém, PA, Brazil.pt_BR
dc.creator.affilliationSecretary of Health of the State of Acre. Rio Branco, AC, Brazil.pt_BR
dc.creator.affilliationFederal University of Maranhão. Sao Luis, MA, Brazil.pt_BR
dc.creator.affilliationFederal University of Ceará. Fortaleza, CE, Brazil.pt_BR
dc.creator.affilliationHarvard Medical School. Brigham and Women’s Hospital. Division of Infectious Disease. Boston, USA.pt_BR
dc.creator.affilliationFederal University of Acre. Rio Branco, AC, Brazil.pt_BR
dc.identifier.doi10.1093/cid/ciaa1148-


xmlui.dri2xhtml.METS-1.0.item-files-head

Thumbnail

xmlui.ArtifactBrowser.ItemViewer.head_parent_collections

xmlui.ArtifactBrowser.ItemViewer.show_simple