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dc.contributor.authorSantos, Anderson Lineu Siqueira dos-
dc.contributor.authorRodrigues, Yan Corrêa-
dc.contributor.authorMelo, Marcos Vinícios Hino de-
dc.contributor.authorSantos, Pabllo Antonny Silva dos-
dc.contributor.authorOliveira, Tatyellen Natasha da Costa-
dc.contributor.authorSardinha, Daniele Melo-
dc.contributor.authorLima, Luana Nepomuceno Gondim Costa-
dc.contributor.authorBrasiliense, Danielle Murici-
dc.contributor.authorLima, Karla Valéria Batista-
dc.date.accessioned2021-01-26T12:22:00Z-
dc.date.available2021-01-26T12:22:00Z-
dc.date.issued2020-
dc.identifier.citationSANTOS, Anderson Lineu Siqueira dos et al. First insights into clinical and resistance features of infections by Klebsiella pneumoniae among oncological patients from a referral center in amazon region, Brazil. Infectious Disease Reports, v. 12, n. 3, p. 110-120, Dec. 2020.pt_BR
dc.identifier.issn2036-7449-
dc.identifier.urihttp://patua.iec.gov.br//handle/iec/4221-
dc.description.abstractAbstract: Klebsiella pneumoniae appears as one of the most prevalent pathogens among cancer patients. The present study investigates the clinical, epidemiological and microbiological aspects related to infections caused by K. pneumoniae in cancer patients treated at an oncology referral center in the state of Pará, Amazon region, Brazil. Between July 2017 to July 2019, an epidemiological, observational, cross-sectional study, with a descriptive and analytical approach was conducted, including patients with confirmed diagnosis of cancer who acquired infection by K. pneumoniae 72 h after hospital admission. K. pneumoniae isolates included in the study were obtained from different clinical materials (blood, urine, catheter tip and bladder catheter, orotracheal secretions, oncological and surgical wounds). Antimicrobial susceptibility testing and molecular detection of the carbapenemase-encoding genes were performed. A high prevalence of MDR K. pneumoniae isolates was observed, including two colistin-resistant isolates and seven isolates harboring blaKPC-1 gene. To conclude, our findings provide the firsts insights into the epidemiology and infection by K. pneumoniae in the state of Pará, Brazil, and may be useful on treatment guidance and establishment of strategies to control the spread of resistance strains of K. pneumoniae in the region.pt_BR
dc.description.sponsorshipThis research was supported by funding from the Fundação de Amparo à Pesquisa do Pará/Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (FAPESPA/CAPES) [Cooperation grant Nº017/2014], Programa Institucional de Bolsas de Iniciação Científica/Fundação Amazônia Paraense de Amparo à Pesquisa/Universidade do Estado do Pará (FAPESPA/UEPA) [Cooperation grant Nº001/2017/PPGBPA], Fundação de Amparo à Pesquisa do Pará/Universidade do Estado do Pará (FAPESPA/UEPA) [Cooperation grant Nº004/2019] and the Instituto Evandro Chagas/Ministério da Saúde/Secretaria de Vigilância em Saúde (IEC/MS/SVS)pt_BR
dc.language.isoengpt_BR
dc.publisherMDPIpt_BR
dc.rightsAcesso Abertopt_BR
dc.titleFirst insights into clinical and resistance features of infections by Klebsiella pneumoniae among oncological patients from a referral center in amazon region, Brazilpt_BR
dc.typeArtigopt_BR
dc.subject.decsPrimaryNeoplasias / patologiapt_BR
dc.subject.decsPrimaryKlebsiella pneumoniae / patogenicidadept_BR
dc.subject.decsPrimaryInfecções por Klebsiella / microbiologiapt_BR
dc.subject.decsPrimaryResistência a Múltiplos Medicamentospt_BR
dc.creator.affilliationState University of Pará. Center of Biological and Health Sciences. Parasite Biology in the Amazon Region . Belém, PA, Brasil.pt_BR
dc.creator.affilliationState University of Pará. Center of Biological and Health Sciences. Parasite Biology in the Amazon Region . Belém, PA, Brasil.pt_BR
dc.creator.affilliationState University of Pará. Center of Biological and Health Sciences. Parasite Biology in the Amazon Region . Belém, PA, Brasil.pt_BR
dc.creator.affilliationState University of Pará. Center of Biological and Health Sciences. Parasite Biology in the Amazon Region . Belém, PA, Brasil.pt_BR
dc.creator.affilliationState University of Pará. Center of Biological and Health Sciences. Parasite Biology in the Amazon Region . Belém, PA, Brasil.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Programa de Pós- Graduação em Epidemiologia e Vigilância em Saúde. Ananindeua, PA, Brasil.pt_BR
dc.creator.affilliationState University of Pará. Center of Biological and Health Sciences. Parasite Biology in the Amazon Region . Belém, PA, Brasil / Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.creator.affilliationMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.creator.affilliationState University of Pará. Center of Biological and Health Sciences. Parasite Biology in the Amazon Region . Belém, PA, Brasil / Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.pt_BR
dc.citation.issue
dc.identifier.doi10.3390/idr12030021-


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