Perspectives on new vaccines against arboviruses using insect-specific viruses as platforms
Carvalho, Valéria Lima
Long, Maureen T
Arthropod-borne viruses (arboviruses) are global pathogens circulating endemically with local explosive outbreaks and constant encroachment into new locations. Few vaccines against arboviruses exist; most for humans are in development or clinical trials. Insect-specific viruses (ISVs) offer a unique platform for expression of arbovirus proteins, through the creation of ISV/arbovirus chimeras. Studies have shown promising results of these vaccines with several advantages over their wild-type counterparts. In this review, we discuss the current status of these potential vaccines using ISVs.
xmlui.dri2xhtml.METS-1.0.item-citationCARVALHO, Valéria Lima; LONG, Maureen T. Perspectives on new vaccines against arboviruses using insect-specific viruses as platforms. Vaccines, v. 9, n. 3, p. 1-9, Mar. 2021.
xmlui.dri2xhtml.METS-1.0.item-decsPrimaryArbovirus / patogenicidade
Vírus / patogenicidade
Vacinas / imunologia
Surtos de Doenças
Literatura de Revisão como Assunto