SAMAM - Artigos Científicos
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Os documentos disponíveis no repositório são de propriedade e responsabilidade de seus autores, conforme a legislação que rege o direito autoral no país (Lei nº 9.610 , de 19.02.98).
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Comprehensive analysis of epigenetics regulation, prognostic and the correlation with immune infiltrates of GPX7 in adult gliomas
(Nature Research, 2022)Gliomas are the most commonly occurring malignant brain tumor characterized by an immunosuppressive microenvironment accompanied by profound epigenetic changes, thus influencing the prognosis. Glutathione peroxidase 7 ... -
Astrocyte-like cells transcriptome changes after exposure to a low and non-cytotoxic MeHg concentration
(Springer, 2022)The central nervous system is the main target of MeHg toxicity and glial cells are the first line of defense; however, their true role remains unclear. This study aimed to identify the global map of human glial-like (U87) ... -
Non-lethal concentration of MeHg causes marked responses in the DNA repair, integrity, and replication pathways in the exposed human salivary gland cell line
(Frontiers Media, 2021)In Brazilian northern Amazon, communities are potentially exposed and vulnerable to methylmercury (MeHg) toxicity through the vast ingestion of fish. In vivo and in vitro studies demonstrated that the salivary glands as a ... -
Comparative chromosome painting in Spizaetus tyrannus and Gallus gallus with the use of macro- and microchromosome probes
(Public Library of Science, 2021)Although most birds show karyotypes with diploid number (2n) around 80, with few macrochromosomes and many microchromosomes pairs, some groups, such as the Accipitriformes, are characterized by a large karyotypic reorganization, ... -
Cytogenetic evidence clarifies the phylogeny of the family Rhynchocyclidae (Aves: Passeriformes)
(MDPI, 2021)The phylogenetic position and taxonomic status of Rhynchocyclidae (Aves: Passeriformes) have been the subject of debate since their first description. In most models, Rhynchocyclidae represents a subfamily-level taxon ... -
Antiviral responses in cancer: boosting antitumor immunity through activation of interferon pathway in the tumor microenvironment
(Frontiers Media, 2021)In recent years, it became apparent that cancers either associated with viral infections or aberrantly expressing endogenous retroviral elements (EREs) are more immunogenic, exhibiting an intense intra-tumor immune cell ... -
Bioaccumulation and human health risks of potentially toxic elements in fish species from the southeastern Carajás Mineral Province, Brazil
(Elsevier, 2022)Anthropogenic activities may have increased the concentrations of potentially toxic elements (PTEs) in fish from the southeastern Carajás Mineral Province in Brazil, which has not yet been studied. The objectives were to ... -
Biodiversity and interannual variation of cyanobacteria density in an estuary of the brazilian amazon
(Academia Brasileira de Ciências, 2021)The influence of environmental variables on planktonic biodiversity is widely known. However, the absence of information about the cyanobacterial community in tropical estuarine regions motivated this work, whose objective ... -
Effects of fluoride on submandibular glands of mice: changes in oxidative biochemistry, proteomic profile, and genotoxicity
(Frontiers Media, 2021)Although fluoride (F) is well-known to prevent dental caries, changes in cell processes in different tissues have been associated with its excessive exposure. Thus, this study aimed to evaluate the effects of F exposure ... -
HPV-associated penile cancer: impact of copy number alterations in miRNA/mRNA interactions and potential druggable targets
(IOS Press, 2021)BACKGROUND: Penile cancer (PeCa) is a rare disease, but its incidence has increased worldwide, mostly in HPV+ patients. Nevertheless, there is still no targeted treatment for this carcinoma. OBJECTIVE: To predict the main ... -
An assessment of health outcomes and methylmercury exposure in munduruku indigenous women of childbearing age and their children under 2 years old
(MDPI, 2021)In line with the 1000-day initiative and the Sustainable Development Goals (SDG) 2 and 3, we present a cross-sectional analysis of maternal health, infant nutrition, and methylmercury exposure within hard-to-reach indigenous ... -
Mercury exposure in Munduruku indigenous communities from Brazilian Amazon: methodological background and an overview of the principal results
(MDPI, 2021)The Amazonian indigenous peoples depend on natural resources to live, but human activities’ growing impacts threaten their health and livelihoods. Our objectives were to present the principal results of an integrated and ... -
Before the dam: a fish-mercury contamination baseline survey at the Xingu river, Amazon basin before the Belo Monte dam
(Springer, 2021)In the last decades, mega-diverse rivers worldwide (e.g., the Amazon and their tributaries) have experienced several human-driven transformations, although impact assessments oftentimes lack baseline data or reference ... -
Genetic polymorphism of delta aminolevulinic acid dehydratase (Alad) gene and symptoms of chronic mercury exposure in Munduruku Indigenous children within the Brazilian amazon
(MDPI, 2021)Abstract: Genetic polymorphisms involved in mercury toxicokinetics and toxicodynamics may be associated with severe mercury toxicity. This study aimed to investigate the impact of an ALAD polymorphism on chronic mercury ... -
Health risk assessment of mercury exposure from fish consumption in Munduruku Indigenous Communities in the Brazilian Amazon
(MDPI, 2021)Fish serves as the principal source of animal protein for the indigenous people of the Amazon, ensuring their food and nutritional security. However, gold mining causes mercury (Hg) contamination in fish, and consequently ... -
Mercury exposures in riverside amazon communities in Para, Brazil
(Elsevier, 2000)Cross-sectional studies were conducted in three riverside communities in the state of Para in the Amazon Region of Brazil. Two of these communities, Brasilia Legal and Sao Luis do Tapajos, are located in a watershed exposed ... -
Evaluation of total mercury concentrations in fish consumed in the municipality of Itaituba, Tapajos River Basin, Para, Brazil
(Elsevier, 2000)The environmental exposure to mercury by riverine and Indian communities can occur through the ingestion of fish and products contaminated by mercury compounds. The present study aims to evaluate the total mercury concentration ... -
Mercury contamination in fish from Santarém, Pará, Brazil
(Elsevier, 2000)This paper reports on total mercury concentrations in edible tissue from 11 fish species caught in the Municipality of Santarém, Tapajós River Basin, Pará State, which are most consumed by the local population and investigates ... -
Mercury contamination of fish and exposures of an indigenous community in Pará state, Brazil
(Elsevier, 2000)Fish consumption is an important source of protein among indigenous communities in Amazonian Brazil. Exposures to mercury via fish were studied in an indigenous community of the Munduruku reserve, located in the Tapajós ... -
Factor analysis applied to metal content in hair: a study on the Correlation between neighborhoods and associated risk - Altamira, Pará, Brazil
(2021)Few studies on capillary metals are conducted in the Amazon region despite the diversity of environmental problems that directly reflect on human health, as is the case of the population of Altamira. The hair matrix was ...
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