SAMAM - Artigos Científicos
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Os documentos disponíveis no repositório são de propriedade e responsabilidade de seus autores, conforme a legislação que rege o direito autoral no país (Lei nº 9.610 , de 19.02.98).
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Kinase inhibition in multiple myeloma: current scenario and clinical perspectives
(MDPI, 2022)Multiple myeloma (MM) is a blood cell neoplasm characterized by excessive production of malignant monoclonal plasma cells (activated B lymphocytes) by the bone marrow, which end up synthesizing antibodies or antibody ... -
Health risk assessment attributed to consumption of fish contaminated with mercury in the Rio Branco basin, Roraima, Amazon, Brazil
(MDPI, 2022)The aim of this study was to assess the health risk attributable to the consumption of mercury-contaminated fish for the urban and non-urban populations living in the Roraima state, Amazon, Brazil. Seventy-five fish ... -
Genomic organization of microsatellites and LINE-1-like retrotransposons: evolutionary implications for Ctenomys minutus (Rodentia: Ctenomyidae) cytotypes
(MDPI, 2022)The Neotropical underground rodents of the genus Ctenomys (Rodentia: Ctenomyidae) comprise about 65 species, which harbor the most significant chromosomal variation among mammals (2n = 10 to 2n = 70). Among them, C. minutus ... -
Intracellular accumulation and DNA damage caused by methylmercury in glial cells
(Wiley, 2022)Mercury is widely used in industrial and extractive processes, and the improper disposal of waste or products containing this metal produces a significant impact on ecosystems, causing adverse effects on living organisms, ... -
Expression of GOT2 Is epigenetically regulated by DNA methylation and correlates with immune infiltrates in clear-cell renal cell carcinoma
(MDPI, 2022)Clear cell renal cell carcinoma (KIRC) is the most common and highly malignant pathological type of kidney cancer, characterized by a profound metabolism dysregulation. As part of aspartate biosynthesis, mitochondrial GOT2 ... -
Determination of heavy metals by inductively coupled plasma optical emission spectrometry in water samples from Lake Iripixi, Oriximina, PA, Brazil
(Springer, 2022)The presented study sheds light on the applicability of inductively coupled plasma optical emission spectrometry (ICP-OES) for the multielement analysis of naturally obtained water. The technique mainly focused on the ... -
Treatment of copper deficient buffaloes through the application of parenteral copper
(Universidade Federal de Minas Gerais. Escola de Veterinária, 2022)The objective of this study was to investigate the effectiveness of the treatment of copper deficiency, by parenteral route, in buffalo calves raised on the Marajó Island (PA). Fourteen animals were divided into two ... -
Evaluation of potentially toxic metals in leaches from solid waste deposition area in Belém-Pará
(Sociedade Brasileira de Química, 2022)The formation of solid waste is a global challenge regarding environmental preservation. Due to the lifestyle of modern society, which aims to improve practicality, new products are constantly being released in the market ... -
Mercury exposure and anemia in children and adolescents from six riverside communities of Brazilian Amazon
(Associação Brasileira de Saúde Coletiva, 2022)Mercury (Hg) is a toxic substance, and fish consumption is one of the main sources of exposure for the population. This article aims to evaluate the association between exposure to Hg and anemia among children and adolescents ... -
Seasonal changes in metal and nutrient fluxes across the sediment-water interface in tropical mangrove creeks in the Amazon region
(Elsevier, 2022)Mangrove creeks are considered important routes between terrestrial and adjacent coastal waters regarding the transport of dissolved material to oceans. The present study assessed if Amazonian seasonal rainfall patterns ... -
Karyotypical confirmation of natural hybridization between two manatee species, Trichechus manatus and Trichechus inunguis
(MDPI, 2022)Two species of manatees are found in Northern Brazil—the Antillean manatee (Trichechus manatus), which is found along the coast from Florida to Northeastern Brazil, and the Amazonian manatee (Trichechus inunguis), endemic ... -
Human risk assessment of toxic elements (As, Cd, Hg, Pb) in marine fish from the Amazon
(Elsevier, 2022)The present study evaluated As, Hg, Pb and Cd burdens in both ecologically and commercially important 314 marine fishes belonging to 47 species sampled along the Amazon Coast. We specifically investigated variations in ... -
High genetic diversity and antimicrobial resistance in Escherichia coli highlight Arapaima gigas (Pisces: Arapaimidae) as a reservoir of quinolone-resistant strains in Brazilian Amazon rivers
(MDPI, 2022)The increasing prevalence of multi-drug resistant (MDR) Escherichia coli in distinct ecological niches, comprising water sources and food-producing animals, such as fish species, has been widely reported. In the present ... -
Evolutionary dynamics of two classes of repetitive DNA in the genomes of two species of Elopiformes (Teleostei, Elopomorpha)
(Mary Ann Liebert, 2022)The order Elopiformes includes fish species of medium to large size with a circumglobal distribution, in both the open sea, coastal, and estuarine waters. The Elopiformes are considered an excellent model for evolutionary ... -
Recurrent chromosome reshuffling and the evolution of neo-sex chromosomes in parrots
(Nature Research, 2022)The karyotype of most birds has remained considerably stable during more than 100 million years’ evolution, except for some groups, such as parrots. The evolutionary processes and underlying genetic mechanism of chromosomal ... -
H. pylori infection and virulence factors cagA and vacA (s and m Regions) in gastric adenocarcinoma from Para State, Brazil
(MDPI, 2022)H. pylori shows a great variability in genes associated with virulence, which may influence properties related to gastric adenocarcinoma initiation and progression. Among them, cagA and vacA show a strong positive association ... -
From molecules to behavior in long-term inorganic mercury intoxication: unraveling proteomic features in cerebellar neurodegeneration of rats
(MDPI, 2022)Abstract: Mercury is a severe environmental pollutant with neurotoxic effects, especially when exposed for long periods. Although there are several evidences regarding mercury toxicity, little is known about inorganic ... -
Effects of long-term fluoride exposure are associated with oxidative biochemistry impairment and global proteomic modulation, but not genotoxicity, in parotid glands of mice
(Public Library of Science, 2022)Background: Fluoride has become widely used in dentistry because of its effectiveness in caries control. However, evidence indicates that excessive intake interferes with the metabolic processes of different tissues. Thus, ... -
DNA damage and proteomic profile changes in rat salivary glands after chronic exposure to inorganic mercury
(Springer Verlag, 2022)Mercury (Hg) is a toxic metal that became a public health problem due to environmental contamination caused by anthropogenic activity. In this sense, oral homeostasis can undergo changes due to the toxic effects of metal ... -
Comprehensive analysis of epigenetics regulation, prognostic and the correlation with immune infiltrates of GPX7 in adult gliomas
(Nature Research, 2022)Gliomas are the most commonly occurring malignant brain tumor characterized by an immunosuppressive microenvironment accompanied by profound epigenetic changes, thus influencing the prognosis. Glutathione peroxidase 7 ...
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