• Portal do Governo Brasileiro
  • Atualize sua Barra de Governo
Logo
    • English
    • español
    • português (Brasil)
    • English
    • español
    • português (Brasil)
  • xmlui.dri2xhtml.structural.login
xmlui.ArtifactBrowser.ItemViewer.trail 
  •   xmlui.general.dspace_home
  • SEÇÃO DE VIROLOGIA
  • SAVIR - Artigos Científicos
  • xmlui.ArtifactBrowser.ItemViewer.trail
  •   xmlui.general.dspace_home
  • SEÇÃO DE VIROLOGIA
  • SAVIR - Artigos Científicos
  • xmlui.ArtifactBrowser.ItemViewer.trail
JavaScript is disabled for your browser. Some features of this site may not work without it.

Effectiveness of the monovalent G1P[8] human rotavirus vaccine against hospitalization for severe G2P[4] rotavirus gastroenteritis in Belém, Brazil

Thumbnail
xmlui.dri2xhtml.METS-1.0.item-date
2011
xmlui.dri2xhtml.METS-1.0.item-files-viewOpen
Effectiveness of the monovalent G1P[8] human rotavirus vaccine against hospitalization for severe G2P[4] rotavirus gastroenteritis in Belém, Brazil.pdf (276.1xmlui.dri2xhtml.METS-1.0.size-kilobytes)
xmlui.mirage2.itemSummaryView.MetaData
xmlui.ArtifactBrowser.ItemViewer.show_full
xmlui.dri2xhtml.METS-1.0.item-uri
http://patua.iec.gov.br/handle/iec/946
xmlui.dri2xhtml.METS-1.0.item-author
Justino, Maria Cleonice Aguiar
Linhares, Alexandre da Costa
Lanzieri, Tatiana. M
Miranda, Ylle
Mascarenhas, Joana D'Arc Pereira
Abreu, Erika
Guerra, Sylvia de Fátima dos Santos
Oliveira, Alessilva S. L
Silva, Veronice B da
Sanchez, Nervo
Meyer, Nadia
Shafi, Fakrudeen
Ortega-Barria, Eduardo
Soriano-Gabarró, Montse
Colindres, Romulo E
xmlui.dri2xhtml.METS-1.0.item-abstract
Background: Brazil initiated universal immunization of infants with the G1P[8] human rotavirus (RV) vaccine in March 2006. This study evaluated vaccine effectiveness (VE) against severe rotavirus gastroenteritis (RVGE) hospitalizations. Methods: Matched case-control study conducted at 4 hospitals in Belém from May 2008 to May 2009. Cases were children hospitalized with RVGE age-eligible to have received 2 doses of the human RV vaccine (≥12 weeks of age and born after March 6, 2006). For each case, 1 neighborhood and 1 hospital control without gastroenteritis was selected, matching by birth date (±8 and ±6 weeks, respectively). Matched odds ratio of 2-dose RV vaccination in cases versus controls was used to estimate VE (1 - odds ratio X 100%). Results: Of 538 RVGE cases, 507 hospital controls and 346 neighborhood controls included, 54%, 61%, and 74% had received both RV vaccine doses. VE against RVGE hospitalization was 75.8% (95% confidence interval [CI]: 58.1–86.0) using neighborhood controls and 40.0% (95% CI: 14.2–58.1) using hospital controls. VE in children 3 to 11 months and ≥12 months of age was 95.7% (95% CI: 67.8–99.4) and 65.1% (95% CI: 37.2–80.6) using neighborhood controls, and 55.6% (95% CI: 12.3–77.5) and 32.1% (95% CI: 3.7–55.5) using hospital controls. G2P[4] accounted for 82.0% of RVGE hospitalizations. G2P[4]-specific VE was 75.4% (95% CI: 56.7–86.0) using neighborhood controls and 38.9% (95% CI: 11.1– 58.0) using hospital controls. Conclusions: Although fully heterotypic G2P[4] was the predominant RV strain, good VE was demonstrated. VE was highest in children aged 3 to 11 month months. However, protection in children ≥12 months of age, important for optimal public health impact, was significantly sustained based on estimates obtained using neighborhood controls.
xmlui.dri2xhtml.METS-1.0.item-citation
JUSTINO, Maria Cleonice Aguiar et al. Effectiveness of the monovalent G1P[8] human rotavirus vaccine against hospitalization for severe G2P[4] rotavirus gastroenteritis in Belém, Brazil. The Pediatric Infectious Disease Journal, v. 30, n. 5, p. 396-401, May 2011
xmlui.dri2xhtml.METS-1.0.item-decsPrimary
Gastroenterite / virologia
Rotavirus / isolamento & purificação
Vacinas contra Rotavirus
Hospitalização
xmlui.dri2xhtml.METS-1.0.item-rights
Acesso Aberto
xmlui.mirage2.itemSummaryView.Collections
  • SAVIR - Artigos Científicos

Instituto Evandro Chagas - SVS - MS - 2007-2018 Rodovia BR316 km 7 sn - Levilandia - 67030-000 - Ananindeua - Para - Brasil.
Licença Creative CommonsEste trabalho está licenciado com uma Licença Creative Commons - Atribuição-NãoComercial 4.0 Internacional
Tel: (55 91) 3214-2191
Email: biblioteca@iec.gov.br / clariceneta@iec.gov.br
 

 

xmlui.ArtifactBrowser.Navigation.head_browse

xmlui.ArtifactBrowser.Navigation.head_all_of_dspacexmlui.ArtifactBrowser.Navigation.communities_and_collectionsxmlui.ArtifactBrowser.Navigation.browse_dateissuedxmlui.ArtifactBrowser.Navigation.browse_authorxmlui.ArtifactBrowser.Navigation.browse_titlexmlui.ArtifactBrowser.Navigation.browse_subjectxmlui.ArtifactBrowser.Navigation.head_this_collectionxmlui.ArtifactBrowser.Navigation.browse_dateissuedxmlui.ArtifactBrowser.Navigation.browse_authorxmlui.ArtifactBrowser.Navigation.browse_titlexmlui.ArtifactBrowser.Navigation.browse_subject

xmlui.EPerson.Navigation.my_account

xmlui.EPerson.Navigation.loginxmlui.EPerson.Navigation.register

Instituto Evandro Chagas - SVS - MS - 2007-2018 Rodovia BR316 km 7 sn - Levilandia - 67030-000 - Ananindeua - Para - Brasil.
Licença Creative CommonsEste trabalho está licenciado com uma Licença Creative Commons - Atribuição-NãoComercial 4.0 Internacional
Tel: (55 91) 3214-2191
Email: biblioteca@iec.gov.br / clariceneta@iec.gov.br