Reactions to rubella vaccine and persistence of antibody in virgin-soil populations after vaccination and wild-virus-induced immunization

xmlui.dri2xhtml.METS-1.0.item-date
1976xmlui.mirage2.itemSummaryView.MetaData
xmlui.ArtifactBrowser.ItemViewer.show_fullxmlui.dri2xhtml.METS-1.0.item-uri
http://patua.iec.gov.br/handle/iec/960xmlui.dri2xhtml.METS-1.0.item-author
Black, Francis Lee
Lamm, Steven H
Emmons, Jean E
Pinheiro Filho, Francisco de Paula
xmlui.dri2xhtml.METS-1.0.item-abstract
Vaccination of two virgin-soil (without historical or serological evidence of past
infection) populations of Amazon lndians with RA 27/3 rubella vaccine was followed
by rever of > 100 F in 10% of the vacinees and by ephemeral arthralgia
in 2 %. These frequencies are not greater than those that have been reported for
cosmopolitan populations of comparable ages. There was little or no secondary
spread of the virus. Titers of hemagglutination-inhibiting antibody to rubella
virus were prevalent in a third population of Amazon lndians, who had naturally
acquired immunity and were unexposed to reinfection, and did not decline
during a period of four to 12 years after infection. Antibody titers in the two
virgin-soil populations immunized with RA 27/3 vaccine declined by twofold between
four months and two and one-half years after vaccination but, at the end
of that period, were not appreciably lower than antibody titers at four years in
the naturally infected population. AlI age groups except chiIdren under one year
of age responded to vaccination equally weII.
xmlui.dri2xhtml.METS-1.0.item-citation
BLACK, Francis L. et al. Reactions to rubella vaccine and persistence of antibody in virgin-soil populations after vaccination and wild-virus-induced immunization. Journal of Infectious Diseases, v. 133, n. 4, p. 393-398, 1976.xmlui.dri2xhtml.METS-1.0.item-decsPrimary
Vacina contra Rubéola / administração & dosagemVacina contra Rubéola / efeitos adversos
Vacina contra Rubéola / uso terapêutico
Vacina contra Rubéola / imunologia
Índios Sul-Americanos