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Cytogenetic, growth rate and virus susceptibility differences in sublines of H. Ep. 2 cells

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1970
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Cytogenetic, growth rate and virus susceptibility differences in sublines of H. Ep. 2 cells .pdf (1.059Mb)
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URI
http://patua.iec.gov.br/handle/iec/969
Autor
Mallmann, M. Clara
Pinheiro Filho, Francisco de Paula
Salzano, F. M
Ayres, M
Resumo
Two sublines of H. Ep. 2, obtained from New Haven (NH) and São Paulo (SP) respectively, were studied in relation to their morphology, growth rate, virus susceptibility and chromosomes. The São Paulo subline was divided into two, one cultivated in Hanks lactalbumin medium plus 20% of calf serum and the other in modified Eagle's medium, to investigate the possible influence of the medium of cultivation on these variables. This influence proved to be small. But significant differences were observed between the two sublines, H. Ep. 2 NH showing a lowered rate of growth, less susceptibility to virus infections and a higher modal chromosome number. The changes in chromosome number were of such a nature that there was practically no overlapping in the range of variation in the two sublines. Groups B, D and F were the most affected.
Referência
MALLMANN, M. Clara et al. Cytogenetic, growth rate and virus susceptibility differences in sublines of H. Ep. 2 cells. Cytologia, v. 35, n. 2, p. 262-270, 1970.
DeCs
Carcinoma
Dermatomicoses / imunologia
Modelos Animais de Doenças
Quelóide
Direito Autoral
Acesso Aberto
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  • SAVIR - Artigos Científicos

Instituto Evandro Chagas - SVS - MS - 2007-2018 Rodovia BR316 km 7 sn - Levilandia - 67030-000 - Ananindeua - Para - Brasil.
Licença Creative CommonsEste trabalho está licenciado com uma Licença Creative Commons - Atribuição-NãoComercial 4.0 Internacional
Tel: (55 91) 3214-2191
Email: biblioteca@iec.gov.br / clariceneta@iec.gov.br
 

 

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Instituto Evandro Chagas - SVS - MS - 2007-2018 Rodovia BR316 km 7 sn - Levilandia - 67030-000 - Ananindeua - Para - Brasil.
Licença Creative CommonsEste trabalho está licenciado com uma Licença Creative Commons - Atribuição-NãoComercial 4.0 Internacional
Tel: (55 91) 3214-2191
Email: biblioteca@iec.gov.br / clariceneta@iec.gov.br